methazolamide (MTZ) - acetazolamide (ATZ) - Carbonic anhydrase inhibitors protect against tau protein build-up
They screened over 1,437 clinically-approved drug compounds and found that carbonic anhydrase inhibitors, of which the glaucoma drug methazolamide is one, remove tau build-up and lessen signs of dementia in zebrafish and mice with mutant forms of tau.
They screened over 1,437 clinically-approved drug compounds and found that carbonic anhydrase inhibitors, of which the glaucoma drug methazolamide is one, remove tau build-up and lessen signs of dementia in zebrafish and mice with mutant forms of tau.