Recent studies by JAMA (news.cancerconnect.com/pros... indicate that Alzheimer's and Dementia risk can be increased by up to 28% with ADT......as if there weren't already enough negatives....
The article also suggests that the risk can be mitigated by taking Viagra, would this interfere with the positive effects of ADT?
Has anybody tried this or have any further information? Too late for me as I'm just coming up to my 20th month of ADT!
Oh Lordy - as if we weren't having enough FUN with side effects
I have been on ADT for 8 years ...
All my life I have claimed: I'm crazy, not stoopid .
now will I have to change it to: I'm demented not stoopid
Ain't it all just one laugh after another
Hang in there men - no one ever promised it was going to be easy
and the beat goes on
PJD
I wonder if substituting ADT for the transdermal E2 patch would mitigate that? I suspect it would as brain fog is supposed to be reduced with estradiol.
Anyone any ideas on that?
"Recent studies by JAMA (news.cancerconnect.com/pros... indicate that Alzheimer's and Dementia risk can be increased by up to 28% with ADT......as if there weren't already enough negatives...."
No they don't. Association is not causation.
Smoking and cancer?
I have never seen anything about smoking and prostate cancer.
Mine doesn't smoke, it's more of a water pistol 😉. I don't think that's by association 🙂
if you are in the cohort that gets associated cardiovascular issues or associated dementia, do you care whether or not the actual causal chain is documented in humans yet?
Yes, of course one cares if adt causes dementia or if there is,say, a genetic cause of both PCa and dementia. If there is no causal link, there is no benefit in stopping adt.
do all side effects listed for drugs have known causes? more than one study notices the association and another finds a possible mechanism in animal studies for the dementia part.
Common prostate cancer treatment tied to dementia, study shows
Kidney Stones after ADT
EMBARK Study: ADT vs Enzalutamide +/- ADT
