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Combination therapy
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Update 7.5
I am interested in the potential of
combination
therapy
but would prefer mono-therapy with Besremi providing I tolerate a higher dose. We will see how things go. So, things are going well. I remain very pleased with my response to Besremi.
I am interested in the potential of
combination
therapy
but would prefer mono-therapy with Besremi providing I tolerate a higher dose. We will see how things go. So, things are going well. I remain very pleased with my response to Besremi.
hunter5582
in
MPN Voice
1 year ago
The T3-4-Hypo trial (Netherlands)
[i]
The T3-4-Hypo trial
[/i] [i]A Dutch national randomized placebo-controlled double-blind multicenter trial of LT4/LT3
combination
therapy
in patients with autoimmune hypothyroidism.
[i]
The T3-4-Hypo trial
[/i] [i]A Dutch national randomized placebo-controlled double-blind multicenter trial of LT4/LT3
combination
therapy
in patients with autoimmune hypothyroidism.
helvella
Thyroid UK
in
Thyroid UK
1 year ago
Does anyone know of a connection between undermedication and histamine intolerance, or if there are histamines in Armour thyroid?
My histamine intolerance symptoms have gone crazy of late, to the extent I've had to significantly change my diet. Histamine intolerance is something I have suffered with on and off for years, but nothing like it is now. I have 2 theories, namely one I am undermedicated or two Armour may be behind
My histamine intolerance symptoms have gone crazy of late, to the extent I've had to significantly change my diet. Histamine intolerance is something I have suffered with on and off for years, but nothing like it is now. I have 2 theories, namely one I am undermedicated or two Armour may be behind
Reefseeker
in
Thyroid UK
11 months ago
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Feeling awful again
therapy
my T3 has dropped a little and my TSH has risen an infinitesimal amount, which are probably related.
therapy
my T3 has dropped a little and my TSH has risen an infinitesimal amount, which are probably related.
Pearlteapot
in
Thyroid UK
1 year ago
Real-World Outcomes of First-Line Ribociclib Plus Aromatase Inhibitor in Patients With HR+/HER2− MBC
"
First-line ribociclib and AI
therapy
for patients with HR+/HER2− MBC is effective and safely deliverable in the real-world setting, albeit with high rates of dose reduction."
"
First-line ribociclib and AI
therapy
for patients with HR+/HER2− MBC is effective and safely deliverable in the real-world setting, albeit with high rates of dose reduction."
Hazelgreen
in
SHARE Metastatic Breast Cancer
1 year ago
Some good Clonoseq results
I started my diagnosis at stage 4, in Summer of 2021 and immediately began
combination
therapy
of Calquence plus . I know it is unusual to reach uMRD with BTKs alone, but I am hopeful to reach it with the combo therapy. KVB-Texas
I started my diagnosis at stage 4, in Summer of 2021 and immediately began
combination
therapy
of Calquence plus . I know it is unusual to reach uMRD with BTKs alone, but I am hopeful to reach it with the combo therapy. KVB-Texas
Kvb-texas
in
CLL Support
1 year ago
So frustrated that endo told me my hypo symptoms are social, emotional and psychological
Thankfully the endo that I was referred to by the GP said I needed
combination
therapy
and over the past 2 years my meds have increased from thyroxine 125mcg/liothyronine 10mcg up to the current 150mcg/40mcg.
Thankfully the endo that I was referred to by the GP said I needed
combination
therapy
and over the past 2 years my meds have increased from thyroxine 125mcg/liothyronine 10mcg up to the current 150mcg/40mcg.
Reefseeker
in
Thyroid UK
1 year ago
What are your thoughts on RELYVRIO previously known as AMX0035? Could it benefit PD patients as well?
RELYVRIO (previously known as AMX0035 in the U.S.) is an oral, fixed-dose
combination
therapy
for the treatment of adults with ALS RELYVRIO significantly slowed the loss of physical function in a randomized, placebo-controlled clinical trial in ALS https://www.alzforum.org/therapeutics/relyvrio
RELYVRIO (previously known as AMX0035 in the U.S.) is an oral, fixed-dose
combination
therapy
for the treatment of adults with ALS RELYVRIO significantly slowed the loss of physical function in a randomized, placebo-controlled clinical trial in ALS https://www.alzforum.org/therapeutics/relyvrio
Hidden
in
Cure Parkinson's
1 year ago
Strategies to Re-Sensitize Castration-Resistant Prostate Cancer to Antiandrogen Therapy
New paper from Spain [1]. "... we will review those strategies and drugs that are able to resensitize cancer cells to previously used treatments through the use of "hinge" treatments with the objective of obtaining an oncological benefit. "
Some examples are:
[i]
bipolar androgen therapy (
New paper from Spain [1]. "... we will review those strategies and drugs that are able to resensitize cancer cells to previously used treatments through the use of "hinge" treatments with the objective of obtaining an oncological benefit. "
Some examples are:
[i]
bipolar androgen therapy (
pca2004
in
Fight Prostate Cancer
1 year ago
blood tests again
I am on
combination
therapy
- Levo one a day and liothyronine 3 times a day. my blood test is at 2pm - first appt with the endocrinologist since starting this dose.
I am on
combination
therapy
- Levo one a day and liothyronine 3 times a day. my blood test is at 2pm - first appt with the endocrinologist since starting this dose.
Sizzles22
in
Thyroid UK
1 year ago
How is thyroid hormone prescribed across the US?
[/i] [i]5/ Next steps:[/i] [i]1) better understand the decision-making process in thyroid hormone treatment[/i] [i]2) measure long-term outcomes/safety of T4 + T3
therapy
(with DTE and
combination
therapy
)[/i] [i]6/ Special thanks to my mentors at @UChicagoMed[/i] [i] and training resources supported
[/i] [i]5/ Next steps:[/i] [i]1) better understand the decision-making process in thyroid hormone treatment[/i] [i]2) measure long-term outcomes/safety of T4 + T3
therapy
(with DTE and
combination
therapy
)[/i] [i]6/ Special thanks to my mentors at @UChicagoMed[/i] [i] and training resources supported
helvella
Thyroid UK
in
Thyroid UK
11 months ago
Use of combination T4/T3 therapy and NDT in Ireland - a questionnaire
Survey of prescrptions of T4,
combination
, and NDT
therapy
in Ireland.
Survey of prescrptions of T4,
combination
, and NDT
therapy
in Ireland.
diogenes
in
Thyroid UK
1 year ago
At the end of my tether...
I tried T4/T3
combination
therapy
and it yielded good results for 3 months and then completely fell of a cliff with symptoms. Today I have been really light headed, nauseous and tinnitus. Its ruined my life and our family life is miserable.
I tried T4/T3
combination
therapy
and it yielded good results for 3 months and then completely fell of a cliff with symptoms. Today I have been really light headed, nauseous and tinnitus. Its ruined my life and our family life is miserable.
joey82
in
Thyroid UK
1 year ago
How can I arm myself for next GP discussion re. new DI02 result? Anyone been through this?
Hi everyone,I got fed up with having 'normal' test results and T4 & T3 being in good ranges but feeling like crap and having persistent hypo symptoms. So I forked out for some more tests including Blue Horizon Thyroid generic testing. A few things came back in the 'yellow' category, but one red which
Hi everyone,I got fed up with having 'normal' test results and T4 & T3 being in good ranges but feeling like crap and having persistent hypo symptoms. So I forked out for some more tests including Blue Horizon Thyroid generic testing. A few things came back in the 'yellow' category, but one red which
Ebx_design
in
Thyroid UK
1 year ago
Stimulants and non stimulant combo question..
Does anyone have any information regarding the
combination
therapy
of Clonidine with a stimulant?
Does anyone have any information regarding the
combination
therapy
of Clonidine with a stimulant?
Bootsie1
in
CHADD's ADHD Parents Together
1 year ago
Don't feel this book has moved things on
However, while advocating
combination
therapy
, the suggested T3 dosage is inadequate to make much of an effect. Also he insists that for optimal dosage TSH must lie within its reference range - hasn't learned anything there! Finally he doesn't mention our work at all.
However, while advocating
combination
therapy
, the suggested T3 dosage is inadequate to make much of an effect. Also he insists that for optimal dosage TSH must lie within its reference range - hasn't learned anything there! Finally he doesn't mention our work at all.
diogenes
in
Thyroid UK
1 year ago
Tea consumption affects the absorption of levothyroxine
(We all know
combination
therapy
is better, including breakfast drinks). I would urge people not to worry about this unless they have absorption problems.
(We all know
combination
therapy
is better, including breakfast drinks). I would urge people not to worry about this unless they have absorption problems.
jimh111
in
Thyroid UK
1 year ago
Genitourinary Cancers Symposium Meeting Coverage, MedPage Today, January 2024
improved PFS versus more hormonal
therapy
, but control arm questioned, January 26, 2024:[/i] https://www.medpagetoday.com/meetingcoverage/mgucs/108451 [i]
Olaparib-Abiraterone in Biomarker-Selected mCRPC Tops Each Agent Alone - In small first-line trial, PFS more than doubled with combination
improved PFS versus more hormonal
therapy
, but control arm questioned, January 26, 2024:[/i] https://www.medpagetoday.com/meetingcoverage/mgucs/108451 [i]
Olaparib-Abiraterone in Biomarker-Selected mCRPC Tops Each Agent Alone - In small first-line trial, PFS more than doubled with combination
cujoe
in
Fight Prostate Cancer
4 months ago
feeling worse after starting NDT
I have known conversion issues hence one of the reasons why me wanting to start straight off with T4/T3
combination
therapy
. Although my core. It’s temperature has increased and the tinging and pins and needles in feet are already feeling a bit better, emotionally I feel dreadful.
I have known conversion issues hence one of the reasons why me wanting to start straight off with T4/T3
combination
therapy
. Although my core. It’s temperature has increased and the tinging and pins and needles in feet are already feeling a bit better, emotionally I feel dreadful.
LucyYoga
in
Thyroid UK
1 year ago
Five Common Supplements That Have Shown Benefit In Glioblastoma Studies
Moreover, the ratio of Bax/Bcl-2 was upregulated in the group of
combination
therapy
with berberine and cisplatin than that with monotherapy alone. Transwell assay data showed that berberine in combination with cisplatin significantly decreased cell migratory ability of MCF-7 cells.
Moreover, the ratio of Bax/Bcl-2 was upregulated in the group of
combination
therapy
with berberine and cisplatin than that with monotherapy alone. Transwell assay data showed that berberine in combination with cisplatin significantly decreased cell migratory ability of MCF-7 cells.
chartist
in
Glioblastoma Support
1 year ago
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