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Doxycycline, small clinical trial
Doxycycline, Azithromycin and Vitamin C (DAV): A potent
combination
therapy
for targeting mitochondria and eradicating cancer stem cells (CSCs) 10.18632/aging.101905
Doxycycline, Azithromycin and Vitamin C (DAV): A potent
combination
therapy
for targeting mitochondria and eradicating cancer stem cells (CSCs) 10.18632/aging.101905
Purple-Bike
in
Advanced Prostate Cancer
9 months ago
Can anyone help
I would prefer to have a medical professional on-side with any treatments I might find myself needing - Im thinking here of possible
combination
therapy
. I fully understand the commissioning issues around the prescribing go t3 and and familiar with the NICE guidelines on thyroid management.
I would prefer to have a medical professional on-side with any treatments I might find myself needing - Im thinking here of possible
combination
therapy
. I fully understand the commissioning issues around the prescribing go t3 and and familiar with the NICE guidelines on thyroid management.
SOT1512
in
Thyroid UK
9 months ago
TAPUR study
. 🙏🏻 Public system only funds CDK4/6 initially ie Ibrance yet it is the AI, Arimadex that invariably fails and
combination
therapy
could be continued with say Verzenio, Fulvestrant as informed by genomics. An analysis suggested CDK4/6 could be held in reserve thus saving money.
. 🙏🏻 Public system only funds CDK4/6 initially ie Ibrance yet it is the AI, Arimadex that invariably fails and
combination
therapy
could be continued with say Verzenio, Fulvestrant as informed by genomics. An analysis suggested CDK4/6 could be held in reserve thus saving money.
muzzatron
in
SHARE Metastatic Breast Cancer
7 months ago
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European Society for Medical Oncology Congress - ESMO 2023 - Two Significant Lutetium Trials -mCRPC
Data from the study showed a median PSA-PSF of 13 months with the
combination
therapy
compared with 7.8 months with enzalutamide alone. Median radiographic PFS was 16 months with the
combination
therapy
compared with 12 months for enzalutamide.
Data from the study showed a median PSA-PSF of 13 months with the
combination
therapy
compared with 7.8 months with enzalutamide alone. Median radiographic PFS was 16 months with the
combination
therapy
compared with 12 months for enzalutamide.
marnieg46
in
Fight Prostate Cancer
9 months ago
EIS-12656, a first-in-class allosteric inhibitor of ALC1: will soon start a phase 1 trial
to PARP or not to PARP.... “EIS-12656 selectively targets tumors with no apparent effects on normal tissues.” ....“Our clinical study will also explore combination therapies that were hindered by combinatorial toxicity in the past.” https://www.bio-m.org/en/news/news-detail/eisbach-bio-announces-fda-clearance-of-ind-application-for-eis
to PARP or not to PARP.... “EIS-12656 selectively targets tumors with no apparent effects on normal tissues.” ....“Our clinical study will also explore combination therapies that were hindered by combinatorial toxicity in the past.” https://www.bio-m.org/en/news/news-detail/eisbach-bio-announces-fda-clearance-of-ind-application-for-eis
Maxone73
in
Advanced Prostate Cancer
2 months ago
Blood results interpretation required
They got better in 2022 when I started
combination
therapy
. However, I do not think I have reached my optimum (whatever that is) because these symptoms persist. I take 100mcgrs of Levo and 15 pf T3 outside food, coffee, milk, iron etc.
They got better in 2022 when I started
combination
therapy
. However, I do not think I have reached my optimum (whatever that is) because these symptoms persist. I take 100mcgrs of Levo and 15 pf T3 outside food, coffee, milk, iron etc.
Carlax
in
Thyroid UK
5 months ago
#AskChatGPT : list of immunotherapy drugs for prostate cancer
As of my last update in January 2022, several immunotherapy drugs have been studied or are currently being investigated for the treatment of prostate cancer. Here are some of the notable ones: Sipuleucel-T (Provenge): Sipuleucel-T is an autologous cellular immunotherapy approved for the treatment
As of my last update in January 2022, several immunotherapy drugs have been studied or are currently being investigated for the treatment of prostate cancer. Here are some of the notable ones: Sipuleucel-T (Provenge): Sipuleucel-T is an autologous cellular immunotherapy approved for the treatment
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
combined therapy help
Hi a little advise if possible: normally levo 125mg and thybon 5mg. A new endo has taken me off thybon to try and work out if I have diabetes inspidius (water balance issues). I think I was slightly too hyper but 3 weeks later and I feel terrible - weight gain, constipation, no apetite. I don’t think
Hi a little advise if possible: normally levo 125mg and thybon 5mg. A new endo has taken me off thybon to try and work out if I have diabetes inspidius (water balance issues). I think I was slightly too hyper but 3 weeks later and I feel terrible - weight gain, constipation, no apetite. I don’t think
DancerLisboa
in
Thyroid UK
3 months ago
Efficacy and safety of new‑generation BTKis (primarily acalabrutinib and zanubrutinib) in CLL/SLL: a systematic review and meta‑analysis
[/i] [i]Despite the superior efficacy of BTKi
combination
therapy
compared to monotherapy, its AEs rates are relatively high. Compared to acalabrutinib, Zanubrutinib may be the preferred monotherapy for CLL. However, randomized-controlled studies are still needed.
[/i] [i]Despite the superior efficacy of BTKi
combination
therapy
compared to monotherapy, its AEs rates are relatively high. Compared to acalabrutinib, Zanubrutinib may be the preferred monotherapy for CLL. However, randomized-controlled studies are still needed.
AussieNeil
Partner
in
CLL Support
9 months ago
Thyroid S in UK
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
Alex_N
in
Thyroid UK
3 months ago
I’m Coco & today Joolsg suggested I post re upcoming NHS Iron Infusion
Hello RLS people I’ve been here for a while reading & learning, getting the impression this is a very well informed serious & supportive community. You’ve helped me understand a lot…but am very aware there’s lots more to get my head around, so thanks for being here! now am about to have this IV
Hello RLS people I’ve been here for a while reading & learning, getting the impression this is a very well informed serious & supportive community. You’ve helped me understand a lot…but am very aware there’s lots more to get my head around, so thanks for being here! now am about to have this IV
Barnclown
in
Restless Legs Syndrome
4 months ago
help with results please
I’d be grateful if anyone could help with results please. I’m on combined therapy 50mg T4 and 35mg T3 TFT 0.02 (0.35-4.94) FT3 4.5 (2.4-6.00) FT4 8.1 (9.00-19.00) B12 433 (187-883) Vit D 126.1 >50 Thank you :)
I’d be grateful if anyone could help with results please. I’m on combined therapy 50mg T4 and 35mg T3 TFT 0.02 (0.35-4.94) FT3 4.5 (2.4-6.00) FT4 8.1 (9.00-19.00) B12 433 (187-883) Vit D 126.1 >50 Thank you :)
Bollieforme
in
Thyroid UK
4 months ago
Input on Timing of Initial ADT after RP/SRT Failed
She was also inclined to delay the start of ADT until my PSA hit 2.0 ng/mL, and she was thinking it would be just ADT and not a
combination
therapy
with an antiandrogen. We really didn't get into the discussion as to whether it would be continuous or intermittent ADT.
She was also inclined to delay the start of ADT until my PSA hit 2.0 ng/mL, and she was thinking it would be just ADT and not a
combination
therapy
with an antiandrogen. We really didn't get into the discussion as to whether it would be continuous or intermittent ADT.
dans_journey
in
Advanced Prostate Cancer
3 months ago
Invitro study shows Delta Tocotrienol overcomes Docetaxel resistence in PCa
Combination
therapy
is one tool used to overcome therapeutic resistance and drug toxicity. Evaluating the combined effect of δ-TT and docetaxel (DTX), we found that δ-TT potentiates DTX cytotoxicity in DU145 cells.
Combination
therapy
is one tool used to overcome therapeutic resistance and drug toxicity. Evaluating the combined effect of δ-TT and docetaxel (DTX), we found that δ-TT potentiates DTX cytotoxicity in DU145 cells.
Graham49
in
Fight Prostate Cancer
11 months ago
BTA and 'T3 does not cross the placenta'
Until the introduction of levothyroxine ALL babies were born to mothers on '
combination
therapy
', usually a
combination
of T3 and T4 from the mother's thyroid. I am asking as part of the Ask for Evidence campaign and will share the response I get publicly.
Until the introduction of levothyroxine ALL babies were born to mothers on '
combination
therapy
', usually a
combination
of T3 and T4 from the mother's thyroid. I am asking as part of the Ask for Evidence campaign and will share the response I get publicly.
jimh111
in
Thyroid UK
11 months ago
Switching from T4-T3 combination to NDT
And should I split it during the day, the way I do with the
combination
therapy
? What should I look for when doing the switch?
And should I split it during the day, the way I do with the
combination
therapy
? What should I look for when doing the switch?
Alex_p
in
Thyroid UK
1 year ago
Thyroid Gland Swelling etc...
I've recently started T3/T4
combination
therapy
again, the first 4 weeks were tough with a major increase in symptoms but things have clamed a little now and I am feeling a little better than when I was on levothyroxine alone.
I've recently started T3/T4
combination
therapy
again, the first 4 weeks were tough with a major increase in symptoms but things have clamed a little now and I am feeling a little better than when I was on levothyroxine alone.
joey82
in
Thyroid UK
1 year ago
testing protocol on T4 and T3
Hi all. Does anyone have any experience/wisdom re a good time to take T3 pre bloods? I currently take it when I wake up which is between 6.20 and 7.30 and in the afternoon between 3.30 and 4.30. I have a first test since starting combined therapy booked and am wondering when I should take what.
Hi all. Does anyone have any experience/wisdom re a good time to take T3 pre bloods? I currently take it when I wake up which is between 6.20 and 7.30 and in the afternoon between 3.30 and 4.30. I have a first test since starting combined therapy booked and am wondering when I should take what.
Topes009
in
Thyroid UK
6 months ago
North of England Endo
Good evening I’m looking for private message replies please on your recommended Endo’s in the North of England. Yorkshire and North East. Not many seem to be listed on Thyroid U.K. list. Someone open to combined therapy. Thank you! Look forward to hearing from you :)
Good evening I’m looking for private message replies please on your recommended Endo’s in the North of England. Yorkshire and North East. Not many seem to be listed on Thyroid U.K. list. Someone open to combined therapy. Thank you! Look forward to hearing from you :)
Bollieforme
in
Thyroid UK
6 months ago
Are We Restoring Thyroid Hormone Signaling in Levothyroxine-Treated Patients With Residual Symptoms of Hypothyroidism?
A practical approach to patients with residual symptoms and on initiation of
combination
therapy
with LT4 + LT3 is provided.
A practical approach to patients with residual symptoms and on initiation of
combination
therapy
with LT4 + LT3 is provided.
helvella
Thyroid UK
in
Thyroid UK
1 year ago
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