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Are We Restoring Thyroid Hormone Signaling in Levothyroxine-Treated Patients With Residual Symptoms of Hypothyroidism?
A practical approach to patients with residual symptoms and on initiation of
combination
therapy
with LT4 + LT3 is provided.
A practical approach to patients with residual symptoms and on initiation of
combination
therapy
with LT4 + LT3 is provided.
helvella
Thyroid UK
in
Thyroid UK
10 months ago
Collagen for Hair Growth?
My hair has got worse (thinning and brittle) since being on T3/T4
combination
therapy
so I've been looking at what makes hair healthy and collagen keeps popping up as good nutritional support.
My hair has got worse (thinning and brittle) since being on T3/T4
combination
therapy
so I've been looking at what makes hair healthy and collagen keeps popping up as good nutritional support.
Piglet1956
in
Thyroid UK
11 months ago
Thyroid Gland Swelling etc...
I've recently started T3/T4
combination
therapy
again, the first 4 weeks were tough with a major increase in symptoms but things have clamed a little now and I am feeling a little better than when I was on levothyroxine alone.
I've recently started T3/T4
combination
therapy
again, the first 4 weeks were tough with a major increase in symptoms but things have clamed a little now and I am feeling a little better than when I was on levothyroxine alone.
joey82
in
Thyroid UK
9 months ago
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Blood results interpretation required
They got better in 2022 when I started
combination
therapy
. However, I do not think I have reached my optimum (whatever that is) because these symptoms persist. I take 100mcgrs of Levo and 15 pf T3 outside food, coffee, milk, iron etc.
They got better in 2022 when I started
combination
therapy
. However, I do not think I have reached my optimum (whatever that is) because these symptoms persist. I take 100mcgrs of Levo and 15 pf T3 outside food, coffee, milk, iron etc.
Carlax
in
Thyroid UK
3 months ago
Recent Pulse article for GPS. 😡
‘Given limited efficacy and long-term safety data around use of liothyronine, long term prescription should be reserved for a very select group of patients with evidence of sustained response to
combination
therapy
,’ the statement concludes.
‘Given limited efficacy and long-term safety data around use of liothyronine, long term prescription should be reserved for a very select group of patients with evidence of sustained response to
combination
therapy
,’ the statement concludes.
Mollyfan
in
Thyroid UK
9 months ago
Pregnancy and t3 only
Should I go on some
combination
therapy
of t4/T3 or just remain as is as I am worried to change anything? Apologies for asking but I am so untrusting of all medical providers that I trust real life opinions much much more. Thanks
Should I go on some
combination
therapy
of t4/T3 or just remain as is as I am worried to change anything? Apologies for asking but I am so untrusting of all medical providers that I trust real life opinions much much more. Thanks
Vickisophieunicorn
in
Thyroid UK
11 months ago
#AskChatGPT : list of immunotherapy drugs for prostate cancer
As of my last update in January 2022, several immunotherapy drugs have been studied or are currently being investigated for the treatment of prostate cancer. Here are some of the notable ones: Sipuleucel-T (Provenge): Sipuleucel-T is an autologous cellular immunotherapy approved for the treatment
As of my last update in January 2022, several immunotherapy drugs have been studied or are currently being investigated for the treatment of prostate cancer. Here are some of the notable ones: Sipuleucel-T (Provenge): Sipuleucel-T is an autologous cellular immunotherapy approved for the treatment
God_Loves_Me
in
Advanced Prostate Cancer
8 days ago
combined therapy help
Hi a little advise if possible: normally levo 125mg and thybon 5mg. A new endo has taken me off thybon to try and work out if I have diabetes inspidius (water balance issues). I think I was slightly too hyper but 3 weeks later and I feel terrible - weight gain, constipation, no apetite. I don’t think
Hi a little advise if possible: normally levo 125mg and thybon 5mg. A new endo has taken me off thybon to try and work out if I have diabetes inspidius (water balance issues). I think I was slightly too hyper but 3 weeks later and I feel terrible - weight gain, constipation, no apetite. I don’t think
DancerLisboa
in
Thyroid UK
14 days ago
Thyroid S in UK
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
helloworl
in
Thyroid UK
24 days ago
I’m Coco & today Joolsg suggested I post re upcoming NHS Iron Infusion
Hello RLS people I’ve been here for a while reading & learning, getting the impression this is a very well informed serious & supportive community. You’ve helped me understand a lot…but am very aware there’s lots more to get my head around, so thanks for being here! now am about to have this IV
Hello RLS people I’ve been here for a while reading & learning, getting the impression this is a very well informed serious & supportive community. You’ve helped me understand a lot…but am very aware there’s lots more to get my head around, so thanks for being here! now am about to have this IV
Barnclown
in
Restless Legs Syndrome
1 month ago
help with results please
I’d be grateful if anyone could help with results please. I’m on combined therapy 50mg T4 and 35mg T3 TFT 0.02 (0.35-4.94) FT3 4.5 (2.4-6.00) FT4 8.1 (9.00-19.00) B12 433 (187-883) Vit D 126.1 >50 Thank you :)
I’d be grateful if anyone could help with results please. I’m on combined therapy 50mg T4 and 35mg T3 TFT 0.02 (0.35-4.94) FT3 4.5 (2.4-6.00) FT4 8.1 (9.00-19.00) B12 433 (187-883) Vit D 126.1 >50 Thank you :)
Bollieforme
in
Thyroid UK
2 months ago
INCA033989 phase 1 clinical trial is recruiting patients
Patients with MF with a suboptimal response to treatment will allow for the evaluation of INCA033989 as an add-on
therapy
in
combination
with ruxolitinib.
Patients with MF with a suboptimal response to treatment will allow for the evaluation of INCA033989 as an add-on
therapy
in
combination
with ruxolitinib.
flamboyant_hawking
in
MPN Voice
10 months ago
testing protocol on T4 and T3
Hi all. Does anyone have any experience/wisdom re a good time to take T3 pre bloods? I currently take it when I wake up which is between 6.20 and 7.30 and in the afternoon between 3.30 and 4.30. I have a first test since starting combined therapy booked and am wondering when I should take what.
Hi all. Does anyone have any experience/wisdom re a good time to take T3 pre bloods? I currently take it when I wake up which is between 6.20 and 7.30 and in the afternoon between 3.30 and 4.30. I have a first test since starting combined therapy booked and am wondering when I should take what.
Topes009
in
Thyroid UK
3 months ago
North of England Endo
Good evening I’m looking for private message replies please on your recommended Endo’s in the North of England. Yorkshire and North East. Not many seem to be listed on Thyroid U.K. list. Someone open to combined therapy. Thank you! Look forward to hearing from you :)
Good evening I’m looking for private message replies please on your recommended Endo’s in the North of England. Yorkshire and North East. Not many seem to be listed on Thyroid U.K. list. Someone open to combined therapy. Thank you! Look forward to hearing from you :)
Bollieforme
in
Thyroid UK
3 months ago
Input on Timing of Initial ADT after RP/SRT Failed
She was also inclined to delay the start of ADT until my PSA hit 2.0 ng/mL, and she was thinking it would be just ADT and not a
combination
therapy
with an antiandrogen. We really didn't get into the discussion as to whether it would be continuous or intermittent ADT.
She was also inclined to delay the start of ADT until my PSA hit 2.0 ng/mL, and she was thinking it would be just ADT and not a
combination
therapy
with an antiandrogen. We really didn't get into the discussion as to whether it would be continuous or intermittent ADT.
dans_journey
in
Advanced Prostate Cancer
6 days ago
New Consultant-Different Plan
therapy
Feb 22 and have been on 100 Levothyroxine and 20 liothyronine (10 am and 10 pm) and feeling greatly improved ever since that time.
therapy
Feb 22 and have been on 100 Levothyroxine and 20 liothyronine (10 am and 10 pm) and feeling greatly improved ever since that time.
Lassithi
in
Thyroid UK
3 months ago
Finally!
Back in July I had a response to a FOI, which I challenged. I sent out numerous emails to different NHS governing bodies. I met a brick wall. Today an email turned up out of the blue from my Health Board. It only took them five months. The complaint was that the blood testing for thyroid did not
Back in July I had a response to a FOI, which I challenged. I sent out numerous emails to different NHS governing bodies. I met a brick wall. Today an email turned up out of the blue from my Health Board. It only took them five months. The complaint was that the blood testing for thyroid did not
serenfach
in
Thyroid UK
5 months ago
FDA approves niraparib and abiraterone acetate plus prednisone for BRCA-mutated metastatic castration-resistant prostate cancer - 08/11/2023
Among all HRR+ patients, the
combination
therapy
resulted in a median rPFS of 16.5 months versus 13.7 months with placebo, a 27% reduction in the hazard ratio (P=0.022).
Among all HRR+ patients, the
combination
therapy
resulted in a median rPFS of 16.5 months versus 13.7 months with placebo, a 27% reduction in the hazard ratio (P=0.022).
cujoe
in
Fight Prostate Cancer
9 months ago
Thyroid Trust Talk by Professor Karol Sikora ​
Combination
therapy
using a little liothyronine allows lower and safer T4 levels.
How can we get endocrinologists to prescribe safer therapy?
The levothyroxine Patient Information Leaflet (PIL) could include a warning: ‘speak to your doctor if you receive a cancer diagnosis’.
Combination
therapy
using a little liothyronine allows lower and safer T4 levels.
How can we get endocrinologists to prescribe safer therapy?
The levothyroxine Patient Information Leaflet (PIL) could include a warning: ‘speak to your doctor if you receive a cancer diagnosis’.
jimh111
in
Thyroid UK
11 months ago
Dual ARi in mCRPCa - Antonarakis = 'Combo of 2 AR-directed agents should not be utilized in clinical practice at this time', MedPage 7/20/23
[i]Antonarakis: This has been the second study of
combination
androgen receptor-targeting
therapy
that has failed to show a survival benefit.
[i]Antonarakis: This has been the second study of
combination
androgen receptor-targeting
therapy
that has failed to show a survival benefit.
cujoe
in
Fight Prostate Cancer
10 months ago
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