Search
Search
About
Log in
Join
Experiences with
Cold Therapy
Posts
Communities
17,158 public posts
Filter results
Supraphysiological Androgens [SPA] Promote Tumor Suppressive Activity of the AR Through cMYC Repression and Recruitment of the DREAM Complex
New study [1]. I have struggled to understand how Denmeade’s BAT (Bipolar Androgen Therapy) depends on supraphysiological levels of androgen (testosterone = ~2,000 ng/dL), considering that Morgentaler’s saturation model has it that androgen receptors [ARs] have all the testosterone they can use at
New study [1]. I have struggled to understand how Denmeade’s BAT (Bipolar Androgen Therapy) depends on supraphysiological levels of androgen (testosterone = ~2,000 ng/dL), considering that Morgentaler’s saturation model has it that androgen receptors [ARs] have all the testosterone they can use at
pca2004
in
Fight Prostate Cancer
1 year ago
Lu177 Long Term Survival
Does anyone have long term survival figures for Lu177 treatment? Is is a one time thing or can it be repeated? Is it easier on the body than ADT? Thanks everyone.
Does anyone have long term survival figures for Lu177 treatment? Is is a one time thing or can it be repeated? Is it easier on the body than ADT? Thanks everyone.
NDJIM
in
Advanced Prostate Cancer
10 months ago
Does kidney function get affected by this?
Hi all, Just got news for my dad that his Kidney is only 60% functioning.. super nervous and anxious to really research online what this means.. is this common after treatment.. is this a really bad sign.. I am super frantic right now and have no idea if this is releated to the prostate cancer, or
Hi all, Just got news for my dad that his Kidney is only 60% functioning.. super nervous and anxious to really research online what this means.. is this common after treatment.. is this a really bad sign.. I am super frantic right now and have no idea if this is releated to the prostate cancer, or
FormulaRob
in
Advanced Prostate Cancer
10 months ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
sweating and tired
I’m having masses of hot flashes and I’m really tired. I’ve lost 10kg over the last three months (deliberately through low carb diet) but I’m thinking that might mean I’m now over medicated because I am less kilos than before. The other possibility is that I’ve not used my hrt patch for a few weeks
I’m having masses of hot flashes and I’m really tired. I’ve lost 10kg over the last three months (deliberately through low carb diet) but I’m thinking that might mean I’m now over medicated because I am less kilos than before. The other possibility is that I’ve not used my hrt patch for a few weeks
Pearlteapot
in
Thyroid UK
10 months ago
TURP and Prostatectomy
I am looking at a prostatectomy, but I had a TURP 8 yrs ago. How does this change the risk factors and my potential quality of life for a prostatectomy? If I did radiation therapy, they would like me to have another TURP to remove some of the prostate that is growing into the bladder before starting
I am looking at a prostatectomy, but I had a TURP 8 yrs ago. How does this change the risk factors and my potential quality of life for a prostatectomy? If I did radiation therapy, they would like me to have another TURP to remove some of the prostate that is growing into the bladder before starting
LandManager
in
Prostate Cancer Network
10 months ago
Advice - supplement and diagnosis
Hi, I'm hoping for some advice on whether to pursue b12 def with my GP.... Some history for me (currently not diagnosed with a B12 deficiency) 2021 - GP - exhausted, burning pain in lower leg, pins and needles in feet, restless legs at night. All blood tests done (inc b12), told all normal, referred
Hi, I'm hoping for some advice on whether to pursue b12 def with my GP.... Some history for me (currently not diagnosed with a B12 deficiency) 2021 - GP - exhausted, burning pain in lower leg, pins and needles in feet, restless legs at night. All blood tests done (inc b12), told all normal, referred
Balloonbbb
in
Pernicious Anaemia Society
10 months ago
HRT and diarrhoea
I started HRT at 49 a few months back, not due to menopausal symptoms, but because I found my testosterone to be at the very bottom of range. The very good private hormone doctor I saw said HRT should balance my hormones and is a better way to increase testosterone than by giving testosterone (it did
I started HRT at 49 a few months back, not due to menopausal symptoms, but because I found my testosterone to be at the very bottom of range. The very good private hormone doctor I saw said HRT should balance my hormones and is a better way to increase testosterone than by giving testosterone (it did
CornishChick
in
Thyroid UK
10 months ago
Strategies to Re-Sensitize Castration-Resistant Prostate Cancer to Antiandrogen Therapy
New paper from Spain [1]. "... we will review those strategies and drugs that are able to resensitize cancer cells to previously used treatments through the use of "hinge" treatments with the objective of obtaining an oncological benefit. "
Some examples are:
[i]
bipolar androgen therapy (
New paper from Spain [1]. "... we will review those strategies and drugs that are able to resensitize cancer cells to previously used treatments through the use of "hinge" treatments with the objective of obtaining an oncological benefit. "
Some examples are:
[i]
bipolar androgen therapy (
pca2004
in
Fight Prostate Cancer
1 year ago
Radiation
I had the standard IMRT for my pca back in 2013. I was told it was a lifetime dose. Is that true with the newer forms of radiation treatment? I am faced with starting a six dose regimen of taxotere now since ADT does not seem to be working according to PSMA scans. My psa remains at 1.8 even though the
I had the standard IMRT for my pca back in 2013. I was told it was a lifetime dose. Is that true with the newer forms of radiation treatment? I am faced with starting a six dose regimen of taxotere now since ADT does not seem to be working according to PSMA scans. My psa remains at 1.8 even though the
sillyoyster
in
Advanced Prostate Cancer
10 months ago
Bio Feedback
Has anyone had success with biofeedback? Our son is 13 and had dyspraxia, he can't locate his pelvic floor so as to engage the sensors at the hospital. Anyone have any suggestions on what we could do? We have 5 more sessions (4 hour round trip plus appointment) so it would be good to try and make
Has anyone had success with biofeedback? Our son is 13 and had dyspraxia, he can't locate his pelvic floor so as to engage the sensors at the hospital. Anyone have any suggestions on what we could do? We have 5 more sessions (4 hour round trip plus appointment) so it would be good to try and make
MrsSquirrel
in
ERIC
1 year ago
Perimenopausal and should I take hrt?
Hello, I am trying to assess whether I am perimenopausal or if I just have the usual under active thyroid symptoms. I'm 42 and struggle with the following symptoms...no sex drive and loss of ongoing dryness, headaches on one side of my head with constant tinnitus on this same side, tiredness and mood
Hello, I am trying to assess whether I am perimenopausal or if I just have the usual under active thyroid symptoms. I'm 42 and struggle with the following symptoms...no sex drive and loss of ongoing dryness, headaches on one side of my head with constant tinnitus on this same side, tiredness and mood
Auntbessy
in
Thyroid UK
10 months ago
Hi All back again
Hope everyone is doing as well as can be expected
Hubby just had psa and testosterone test after being on Zoladex again this past nine months, this is his second round after having 6 weeks radiation and 2 years zoladex in 2013 inbetween 2015 and 2023 under control with watch and wait until
Hope everyone is doing as well as can be expected
Hubby just had psa and testosterone test after being on Zoladex again this past nine months, this is his second round after having 6 weeks radiation and 2 years zoladex in 2013 inbetween 2015 and 2023 under control with watch and wait until
Knittingque
in
Advanced Prostate Cancer
10 months ago
bowel endo issues
Hi all, I have deep infiltrated endo on my bowel (diagnosed via scan and mri 3 years ago) and superficial on my uterus but my bowel issues have been getting worse lately probably after all the pain medications and hormone treatment i’ve been trialling to avoid surgery! It’s to the point now I can
Hi all, I have deep infiltrated endo on my bowel (diagnosed via scan and mri 3 years ago) and superficial on my uterus but my bowel issues have been getting worse lately probably after all the pain medications and hormone treatment i’ve been trialling to avoid surgery! It’s to the point now I can
Karen_92
in
Endometriosis UK
10 months ago
I had a novasure 9 years ago. Very successful results. Now I’m on HRT and utrogestan isn’t agreeing with me. Can I have the mirena coil?
I had a novasure 9 years ago. Very successful results. Now I’m on HRT and utrogestan isn’t agreeing with me. Can I have the mirena coil?
I had a novasure 9 years ago. Very successful results. Now I’m on HRT and utrogestan isn’t agreeing with me. Can I have the mirena coil?
Rubberduckling
in
BASHH
10 months ago
Natural FET possibly cancelled
I had a failed fresh transfer at the beginning of June. The plan was made to try for a natural modified FET this month as my cycles are regular and the risk of prenatal hypertension with a hormone FET was not ideal for me. I had my day 10 scan on Thurs and my dominant follicle was already 14.5mm but
I had a failed fresh transfer at the beginning of June. The plan was made to try for a natural modified FET this month as my cycles are regular and the risk of prenatal hypertension with a hormone FET was not ideal for me. I had my day 10 scan on Thurs and my dominant follicle was already 14.5mm but
SMBCnewbie
in
Fertility Network UK
10 months ago
Parent of Adult child refusing change
my adult daughter who is over 40, single and cannot hold a job, is constantly late, has difficulty with cleaning her spaces, delays her medical care, etc... and cannot support herself. She refuses to apply for benefits and is extremely resistant to behavioral therapy relying only on her medication
my adult daughter who is over 40, single and cannot hold a job, is constantly late, has difficulty with cleaning her spaces, delays her medical care, etc... and cannot support herself. She refuses to apply for benefits and is extremely resistant to behavioral therapy relying only on her medication
Password5
in
CHADD's Adult ADHD Support
1 year ago
dilemma ADT duration
apologies first for another longish verbose posting ! I am in a dilemma after my last oncology appointment - I have T2cN0M0 G9 locally contained PCa following a failed HIFU that was previously twice biopsied as G7. After a clear PSMA showing locally contained with no SV involvement I had 20x3Gy to
apologies first for another longish verbose posting ! I am in a dilemma after my last oncology appointment - I have T2cN0M0 G9 locally contained PCa following a failed HIFU that was previously twice biopsied as G7. After a clear PSMA showing locally contained with no SV involvement I had 20x3Gy to
SimMartin
in
Advanced Prostate Cancer
10 months ago
Cognitive behavioural therapy
Hi, I've posted here before so just a quick update - RLS for 47 years, tried DAs, Gabapentin, Pregabalin and on Tramadol at the moment. I've been through augmentation. Tramadol is helping a bit but my sleep pattern is all over the place and I keep falling asleep in the afternoon. My daughter has had
Hi, I've posted here before so just a quick update - RLS for 47 years, tried DAs, Gabapentin, Pregabalin and on Tramadol at the moment. I've been through augmentation. Tramadol is helping a bit but my sleep pattern is all over the place and I keep falling asleep in the afternoon. My daughter has had
restlessinlondon
in
Restless Legs Syndrome
10 months ago
Et triple negative platlets gone up to 1560
Hi all, Just getting back on here about platlets increasing over 1500,My hematologist will want me on hydroxyurea as he said when I go over 1500 that is his way forward. The past 2 bloods I had done have come down from 1420 to 1402 to 1300 last time 6 weeks ago. I am just wondering if it has to be this
Hi all, Just getting back on here about platlets increasing over 1500,My hematologist will want me on hydroxyurea as he said when I go over 1500 that is his way forward. The past 2 bloods I had done have come down from 1420 to 1402 to 1300 last time 6 weeks ago. I am just wondering if it has to be this
Mike1974
in
MPN Voice
1 year ago
Back pain
Apologies in advance for the long post After a bit of a battle with Rheumatology I had a Pet scan back in February that was suggestive of mild PMR They had previously diagnosed me with Fibromyalgia at the age of 51 as I was far to young for PMR and my blood work was unremarkable I was given 15mg of Pred
Apologies in advance for the long post After a bit of a battle with Rheumatology I had a Pet scan back in February that was suggestive of mild PMR They had previously diagnosed me with Fibromyalgia at the age of 51 as I was far to young for PMR and my blood work was unremarkable I was given 15mg of Pred
Northernnugget
in
PMRGCAuk
10 months ago
1
...
90
91
92
...
100
Next page
50
60
70
80
90
100
Filter results
Clear filters
Posted in
All communities
Advanced Prostate Cancer
4429 results
Thyroid UK
2520 results
Endometriosis UK
1875 results
View top 10 communities
Sort by
Most Relevant
Newest