Search
Search
About
Log in
Join
Experiences with
Castration
Posts
Communities
1,150 public posts
Filter results
After Zofigo, what next?
I've read about the Eclipse trial (Pluvicto, 177Lu-PSMA-I&T versus Hormone Therapy in Patients with Metastatic
Castration
-Resistant Prostate Cancer) that is available here in Orlando. It looks like he'd qualify 12 weeks post-Zofigo.
I've read about the Eclipse trial (Pluvicto, 177Lu-PSMA-I&T versus Hormone Therapy in Patients with Metastatic
Castration
-Resistant Prostate Cancer) that is available here in Orlando. It looks like he'd qualify 12 weeks post-Zofigo.
Tinuriel
in
Advanced Prostate Cancer
1 year ago
Squalene Monooxygenase
." *** A 2021 Chinese paper [4] reported that: "Our study revealed that SQLE is involved in the progression of
castration
resistance in CRPC through mediating metabolic reprogramming, presenting SQLE as a new target for the treatment of mCRPC." *** I should mention here that: "Inhibitors of squalene
." *** A 2021 Chinese paper [4] reported that: "Our study revealed that SQLE is involved in the progression of
castration
resistance in CRPC through mediating metabolic reprogramming, presenting SQLE as a new target for the treatment of mCRPC." *** I should mention here that: "Inhibitors of squalene
pjoshea13
in
Fight Prostate Cancer
2 years ago
BATMAN
"ADT" is a red herring, in that there is no meaningful use of
castration
. I know from experience that testosterone cypionate injected into thigh muscle lingers. It fades away slowly.
"ADT" is a red herring, in that there is no meaningful use of
castration
. I know from experience that testosterone cypionate injected into thigh muscle lingers. It fades away slowly.
pca2004
in
Fight Prostate Cancer
2 years ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
A List for Newly Diagnosed that My Wife did in 2022 please add to list if anything is missed or wrong or needs updating. TIA
Bat Therapy BIPOLAR ANDROGEN THERAPY (BAT): A Treatment Option for Metastatic
Castration
-Resistant Prostate Cancer (mCRPC).
Bat Therapy BIPOLAR ANDROGEN THERAPY (BAT): A Treatment Option for Metastatic
Castration
-Resistant Prostate Cancer (mCRPC).
Shorehousejam
in
Advanced Prostate Cancer
10 months ago
What first?: Provenge or Nubeqa?
The patient/author feels confident that doing provenge very early in
castration
resistance, is the better option.
The patient/author feels confident that doing provenge very early in
castration
resistance, is the better option.
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
Docetaxel Extends Enzalutamide Effectiveness
It also shows that triplet therapy may be beneficial in patients who have already progressed to
castration
resistance. We would expect a larger effect if used at the first sign of
castration
resistance. https://www.prostatecancer.news/2022/10/docetaxel-extends-enzalutamide.html
It also shows that triplet therapy may be beneficial in patients who have already progressed to
castration
resistance. We would expect a larger effect if used at the first sign of
castration
resistance. https://www.prostatecancer.news/2022/10/docetaxel-extends-enzalutamide.html
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
PSA fluctuations on docetaxel?
(Note: this is his first time being on chemo as he’s never been on chemotherapy before and he has had
castration
-resistant PC for 11 years, metastasized to the pelvis in 2019. He’ll be on dose #7 of docetaxel as of tomorrow).
(Note: this is his first time being on chemo as he’s never been on chemotherapy before and he has had
castration
-resistant PC for 11 years, metastasized to the pelvis in 2019. He’ll be on dose #7 of docetaxel as of tomorrow).
PHnerd
in
Advanced Prostate Cancer
1 year ago
Is it useful to get a PSMA-PET scan with low volume cancer, newly castration resistant and PSA below 1?
I was
castration
sensitive at the time of all those scans. I am now
castration
resistant and psa six weeks ago was .33 (up from .14&.20 in August). I don't mind doing the PSMA-PET scan again if it is of value.
I was
castration
sensitive at the time of all those scans. I am now
castration
resistant and psa six weeks ago was .33 (up from .14&.20 in August). I don't mind doing the PSMA-PET scan again if it is of value.
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
More from PubMed
Deep, rapid, and durable prostate-specific antigen decline with apalutamide plus androgen deprivation therapy is associated with longer survival and improved clinical outcomes in TITAN patients with metastatic
castration
-sensitive prostate cancer.
Deep, rapid, and durable prostate-specific antigen decline with apalutamide plus androgen deprivation therapy is associated with longer survival and improved clinical outcomes in TITAN patients with metastatic
castration
-sensitive prostate cancer.
Magnus1964
in
Advanced Prostate Cancer
1 year ago
Is ADT beneficial after castration resistance sets in?
Is that because the ADT would be slowing some
castration
sensitive cancer, even though the
castration
resistant cancer is growing separately?
Is that because the ADT would be slowing some
castration
sensitive cancer, even though the
castration
resistant cancer is growing separately?
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
Lu-177-PSMA-I&T for low volume Metastatic Castration-Resistant Prostate Cancer
Is anyone familiar with Lu-177-PSMA-I&T for Metastatic
Castration
-Resistant ogliometastatic spine mets? Compared to chemo? Survival time increase? Side effects?
Is anyone familiar with Lu-177-PSMA-I&T for Metastatic
Castration
-Resistant ogliometastatic spine mets? Compared to chemo? Survival time increase? Side effects?
SViking
in
Advanced Prostate Cancer
2 years ago
Michael T Schweizer & BAT [Bipolar Androgen Therapy
Resistance develops in part because
castration
-resistant prostate cancer (CRPC) cells adaptively up-regulate AR levels through overexpression, amplification, and expression of ligand-independent variants in response to chronic exposure to a low-testosterone environment."
Resistance develops in part because
castration
-resistant prostate cancer (CRPC) cells adaptively up-regulate AR levels through overexpression, amplification, and expression of ligand-independent variants in response to chronic exposure to a low-testosterone environment."
pca2004
in
Fight Prostate Cancer
2 years ago
Cytoreductive Prostatectomy & Oligometastatic PCa.
. “… time to {
castration
-resistant prostate cancer} was statistically significant in the {cytoreductive prostatectomy} group in all analyses ({randomized controlled trial}; HR=0.44 …) ({non-randomized controlled trials}; HR=0.64 …). “… {cancer-specific-survival} was not statistically different
. “… time to {
castration
-resistant prostate cancer} was statistically significant in the {cytoreductive prostatectomy} group in all analyses ({randomized controlled trial}; HR=0.44 …) ({non-randomized controlled trials}; HR=0.64 …). “… {cancer-specific-survival} was not statistically different
pca2004
in
Fight Prostate Cancer
1 year ago
The Thymus & ADT
Many years ago, I discovered that
castration
could cause the thymus to regenerate. I wondered what that meant for PCa patients. There didn't seem to be any interest in the literature. For those who like sweetbreads (as I do), you will be eating the thymus gland.
Many years ago, I discovered that
castration
could cause the thymus to regenerate. I wondered what that meant for PCa patients. There didn't seem to be any interest in the literature. For those who like sweetbreads (as I do), you will be eating the thymus gland.
pca2004
in
Fight Prostate Cancer
2 years ago
Help: Metastasized Castration Resistant Prostate Cancer!
— Yesterday my current doctor of the 5, given me in 16+ months, told me that I had
castration
-resistant prostate cancer and asked me in my second meeting with him if I had a living will. He told me that I may live a year or two at most.
— Yesterday my current doctor of the 5, given me in 16+ months, told me that I had
castration
-resistant prostate cancer and asked me in my second meeting with him if I had a living will. He told me that I may live a year or two at most.
Yin-Yin
in
Advanced Prostate Cancer
2 years ago
European Society for Medical Oncology Congress - ESMO 2023 - Two Significant Lutetium Trials -mCRPC
https://www.urotoday.com/conference-highlights/esmo-2023/esmo-2023-prostate-cancer/147459-esmo-2023-enza-p-anzup-1901-enzalutamide-and-177lu-psma-617-in-poor-risk-metastatic-
castration
-resistant-prostate-cancer-mcrpc-a-randomized-phase-2-trial.html?
https://www.urotoday.com/conference-highlights/esmo-2023/esmo-2023-prostate-cancer/147459-esmo-2023-enza-p-anzup-1901-enzalutamide-and-177lu-psma-617-in-poor-risk-metastatic-
castration
-resistant-prostate-cancer-mcrpc-a-randomized-phase-2-trial.html?
marnieg46
in
Fight Prostate Cancer
10 months ago
PTEN loss is not a determinant of time to castration-resistance following androgen-deprivation therapy in prostate cancer
Keywords: ADT; CRPC; Jordan; PTEN;
castration
resistance; prostate cancer. ©2023 JOURNAL of MEDICINE and LIFE.
Keywords: ADT; CRPC; Jordan; PTEN;
castration
resistance; prostate cancer. ©2023 JOURNAL of MEDICINE and LIFE.
Magnus1964
in
Advanced Prostate Cancer
1 year ago
Efficacy and safety of BAT in CRPC following Abi or Enza resistance: A systematic review
"Bipolar androgen therapy (BAT) is a new endocrinologic treatment for
castration
-resistant prostate cancer (CRPC) that can restore some patients' sensitivity to drugs such as abiraterone (Abi) and enzalutamide (Enz). ...
"Bipolar androgen therapy (BAT) is a new endocrinologic treatment for
castration
-resistant prostate cancer (CRPC) that can restore some patients' sensitivity to drugs such as abiraterone (Abi) and enzalutamide (Enz). ...
pjoshea13
in
Fight Prostate Cancer
1 year ago
PSA and Testosterone
I am of the understanding that the intent of medical
castration
is to reduce T levels so low that it will reduce PSA … I’d expect if my T is so high, I’d assume that my cancer cells would be on a Testosterone feeding frenzy, but instead, PSA has almost stabilized since the last.
I am of the understanding that the intent of medical
castration
is to reduce T levels so low that it will reduce PSA … I’d expect if my T is so high, I’d assume that my cancer cells would be on a Testosterone feeding frenzy, but instead, PSA has almost stabilized since the last.
Vp7174
in
Advanced Prostate Cancer
2 years ago
PSA #’s elevated from sex (After ADT and RT)
I’ve been on Active Surveillance since completing my ADT and RT both in 2017 &18 finally coming out of
castration
in 2019 / early 2020 with a basement T level, so I began Penile Rehab. Well over a year after that, I was able to resume (what I now refer to as) sexual relations with my wife!
I’ve been on Active Surveillance since completing my ADT and RT both in 2017 &18 finally coming out of
castration
in 2019 / early 2020 with a basement T level, so I began Penile Rehab. Well over a year after that, I was able to resume (what I now refer to as) sexual relations with my wife!
Jimhoy
in
Prostate Cancer Network
2 years ago
1
...
10
11
12
...
58
Next page
10
20
30
40
50
Filter results
Clear filters
Posted in
All communities
Advanced Prostate Cancer
1024 results
Fight Prostate Cancer
70 results
Prostate Cancer Network
25 results
View top 10 communities
Sort by
Most Relevant
Newest