Experiences with

Carbidopa

Has anyone heard of Carbidopa and Levidopa and what type of drug are they, this is what my GP has suggested I try. Any advice would be appriciated. Keith

I would like to find a neurologist who is willing to listen to my experiences and work with me, including prescribing carbidopa to take with mucuna. I have only had a horrible experience with the neuro I saw. How did you find an open-minded neurologist? I am in North Carolina, if that helps.

Ich habe Probleme mit meinen unruhigen Beinen - hauptsächlich ständiges Kribbeln und Schwäche große Schwäche in den Beinen - und überlege, ob ich es mit GABA versuchen soll, denn Levidopa/Carbidopa und auch das Neupro Pflaster zeigen kaum Wirkung.

I've been taking Carbidopa/Levodopa for almost a year, and it's been highly helpful in reducing PD symptoms. How might supplements containing mucuna pruriens (like DopaBoost) interact with my prescription?

Went back to the neurologist and switched me back to carbidopa along with amantadine twice a day and as soon as my dosage of carbidopa titrates up from the half pill three times a day to 2 half pills and one full pill daily I start to get the same side effects of contractions/ punching in the gut and

I have problems with my restless legs - mainly constant tingling and weakness in my legs - and am considering whether I should try GABA (as nutritional supplement), since Levidopa/Carbidopa and the Neupro patch have hardly any effect.

Just got home after a neurologist appointment where he suggested I start taking DAs because he thinks I am on too much Carbidopa/Levodopa. I declined.

I just read that extended release Carbidopa/Levodopa taken at bedtime could be a solution. Anyone know anything about this?

https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1529932/abstract

Anyone taking Nourianz and Gocovori together with Carbidopa /Levodopa? I am following this regimen which has been largely benign. Just wanted to know if anyone else has experiences to share.

So I ended up with two different doses that I take during the day along with carbidopa. My morning dose is 1/16+1/64 tsp of Barlowe's + about 2mg of carbidopa ([i]I cut a 25 mg pill in 8ths.

Diagnosed in 2022, late onset at age 75 with slight symptoms before. Slightly dragging my left foot and unable to run was alarming and led me to get checked out. A recommended DATSCAN REVEALED a Dopamine shortage but not severe. Very slight additional symptoms. Doc recommended a very low dose initially

She is on CR Levadopa Carbidopa 175mg per day. Ropinirole CR 4 mg, Safinamide 100mg. Her essential proble is peak dose dsykinesia and fatigue closed to off times. The doctor also prescribed Rivamer 1.5. This seems to be cholinesterase inhibitor. Does thisdo good for PD?

Has anyone been able to find a good source of information to understand proper dosing of mucuna pruriens supplements when taking 25-100 g of carbidopa/levidopa x 3/day?

I have stopped using Neupro patches, but still have to take 3 x 100 mg Levodopa/Carbidopa because I also have Parkinson. For the first time I took 100 mg Gabapentin at 8 pm. It made me feel dazed. I went to bed at 11 pm. My legs didn't realy feel calm.

It has always been a problem for me that it takes a long time for my Carbidopa Levadopa to get into my system and bring "on" time. If my digestive system is slowed down, won't this greatly affect the ability of my meds to get into my system?

The plasma half-life of levodopa is about 50 minutes, without carbidopa. When carbidopa and levodopa are administered together, the half-life of levodopa is increased to about 1.5 hours. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?

I also have Parkinson's and that along with carbidopa/levodopa type medication causes slow intestinal motility, constipation and all kinds of digestive issues. I have to take Miralax and other laxatives daily that don't work that great.

I’m on rasagiline and sometimes mucuna and carbidopa….and should they be discontinued before? If so, how long before? Thanks!

What do you do when carbidopa-levodopa "off" times get inconsistent, more frequent, or it seems the C/L didn't work at all? I get extremely uncomfortable, uncoordinated and so incredibly weak.Thank you!