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Small Molecules, STARs Treat Cell Models of GBA1-linked Parkinson’s
For Parkinson’s, the cells were engineered into dopaminergic neurons (nerve cells that make the signaling molecule dopamine), as this disease is caused by the
death
and dysfunction of these neurons in the
brain
.
For Parkinson’s, the cells were engineered into dopaminergic neurons (nerve cells that make the signaling molecule dopamine), as this disease is caused by the
death
and dysfunction of these neurons in the
brain
.
Hidden
in
Cure Parkinson's
3 years ago
Sinemet intake blocked by Proteins
I was diagnosed in 1992 and have had DBS surgery. At 73, I am actually quite healthy. My question deals with protein intake due to Sinemet being blocked by animal and even quite a few plant proteins, namely amino acid foods. Are the other Parkinson drugs also sensitive to proteins? Has anyone else
I was diagnosed in 1992 and have had DBS surgery. At 73, I am actually quite healthy. My question deals with protein intake due to Sinemet being blocked by animal and even quite a few plant proteins, namely amino acid foods. Are the other Parkinson drugs also sensitive to proteins? Has anyone else
annmariebaird
in
Cure Parkinson's
3 years ago
Parkinsons, DBS, Covid19 Pfizer Vaccine
My wife had DBS 10/2020. Everything isn't back to normal but they are much much much better than before DBS. All tremors and difficult times were gone. She received her 1st Pfizer Covid vaccine shot 3/29/2021. On 4/6/2021 she started to have breakthrough tremors and can barely walk without help. The
My wife had DBS 10/2020. Everything isn't back to normal but they are much much much better than before DBS. All tremors and difficult times were gone. She received her 1st Pfizer Covid vaccine shot 3/29/2021. On 4/6/2021 she started to have breakthrough tremors and can barely walk without help. The
royal57
in
Cure Parkinson's
3 years ago
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Present and future of subthalamotomy in the management of Parkinson´s disease: a systematic review
Article highlights The subthalamic nucleus (STN) plays a key role in the pathophysiology of Parkinson´s disease (PD). Neurosurgical targeting of the STN with Deep Brain Stimulation is a worldwide procedure for PD. Ablation of the STN with Radio Frequency has also been undertaken in several hundred
Article highlights The subthalamic nucleus (STN) plays a key role in the pathophysiology of Parkinson´s disease (PD). Neurosurgical targeting of the STN with Deep Brain Stimulation is a worldwide procedure for PD. Ablation of the STN with Radio Frequency has also been undertaken in several hundred
Farooqji
in
Cure Parkinson's
3 years ago
PTT - Pallidothalamic Tractotomy
Hi, My father has parkinson's for 15 years and I am trying to halt progression in some of the ways you all have. My father's issue has always been freezing and energy / just feeling unwell on days that freezing is predominant. PTT, are there any outcomes on freezing specifically? His DBS has essentially
Hi, My father has parkinson's for 15 years and I am trying to halt progression in some of the ways you all have. My father's issue has always been freezing and energy / just feeling unwell on days that freezing is predominant. PTT, are there any outcomes on freezing specifically? His DBS has essentially
simonasays
in
Cure Parkinson's
3 years ago
DBS
I want to know your experience with DBS
I want to know your experience with DBS
gigi9
in
Cure Parkinson's
3 years ago
Snoo
I have had PMR for many years and am in fact now labelled inflammatory arthritis. The signs and symptoms are the same as is the treatment on and off Pred. I had shingles badly about three years ago and this year will qualify for the shingles vaccine. Has anybody had the vaccine while on Pred and were
I have had PMR for many years and am in fact now labelled inflammatory arthritis. The signs and symptoms are the same as is the treatment on and off Pred. I had shingles badly about three years ago and this year will qualify for the shingles vaccine. Has anybody had the vaccine while on Pred and were
Snoopy7
in
PMRGCAuk
3 years ago
Viral meningitis
I have had VM, unfortunately the virus was not a usual strain so I did not respond to any IV treatments they usually give to VM patients. I had to fight it myself with a temp of 40.2. How long will the headaches last? Been in hospital 3 weeks only recently discharged and scared for the future .Any advice
I have had VM, unfortunately the virus was not a usual strain so I did not respond to any IV treatments they usually give to VM patients. I had to fight it myself with a temp of 40.2. How long will the headaches last? Been in hospital 3 weeks only recently discharged and scared for the future .Any advice
UptoonGirl1
in
Meningitis Now
3 years ago
Does shingles cause Hashimoto’s to flare up?
I have had Hashimoto’s now for about 3 years and I’m still finding it hard navigating my way through the symptoms and flare ups. I have suffered from very bad crippling anxiety over the last year and half which hasn’t helped with the lockdown and dealing a 4 year old and 1.5 year old while attempting
I have had Hashimoto’s now for about 3 years and I’m still finding it hard navigating my way through the symptoms and flare ups. I have suffered from very bad crippling anxiety over the last year and half which hasn’t helped with the lockdown and dealing a 4 year old and 1.5 year old while attempting
Purple_dog
in
Thyroid UK
3 years ago
Lyme's Disease long term arthritis
Is there anyone out there who has long term joint issues due to Lyme's Disease. I had it in 2019 but now struggle to walk 1 mile due to my knees apparently having crumbled and I have cysts on the cartlidge too. Is anyone having similar problems please ? Any advice too thanks.
Is there anyone out there who has long term joint issues due to Lyme's Disease. I had it in 2019 but now struggle to walk 1 mile due to my knees apparently having crumbled and I have cysts on the cartlidge too. Is anyone having similar problems please ? Any advice too thanks.
Bessie22
in
Pain Concern
3 years ago
MrHave PMR currently reducing am on 8mg...now have shingles should I increase pred?
PMR and Shingles
PMR and Shingles
Devon21
in
PMRGCAuk
3 years ago
Theranostics Promising article, I'd like to hear feedback from the Forum. Does anybody else have experience with this treatment,
He is developing molecules at the Loma Linda clinic that he hopes in the future can be sent in to find and treat breast cancer and glioblastomas, currently a
death
-sentence
brain
cancer. "This is exciting. It's very exciting." he said. "We can win this war." COURTESY OF LOMA LINDA UNIVERSITY
He is developing molecules at the Loma Linda clinic that he hopes in the future can be sent in to find and treat breast cancer and glioblastomas, currently a
death
-sentence
brain
cancer. "This is exciting. It's very exciting." he said. "We can win this war." COURTESY OF LOMA LINDA UNIVERSITY
Zzzgott
in
Advanced Prostate Cancer
3 years ago
The Brain Tumour Charity support teams now on Instagram!
Alongside the charity's main Instagram account, we have launched a dedicated support account - @thebraintumourcharity_support Follow us to find out more about our services, as well as information and advice to help you cope with a brain tumour diagnosis. https://www.instagram.com/thebraintumourcharity_support
Alongside the charity's main Instagram account, we have launched a dedicated support account - @thebraintumourcharity_support Follow us to find out more about our services, as well as information and advice to help you cope with a brain tumour diagnosis. https://www.instagram.com/thebraintumourcharity_support
Shannon_TBTC
Partner
in
Acoustic Neuroma Support
3 years ago
FUS vs. DBS An interesting debate on twitter
Expert's favour DBS over FUS
Expert's favour DBS over FUS
Farooqji
in
Cure Parkinson's
3 years ago
Lot of questions re DBS lately. Everything you could want to know.
Chapter 1 Introduction to Surgical Therapies for Parkinson’s Disease ............4 Chapter 2 An Overview of Deep Brain Stimulation (DBS) Therapy...............8 Chapter 3 Risks and Complications of DBS ..................................................19 Chapter 4 Is DBS Right for You? ...........
Chapter 1 Introduction to Surgical Therapies for Parkinson’s Disease ............4 Chapter 2 An Overview of Deep Brain Stimulation (DBS) Therapy...............8 Chapter 3 Risks and Complications of DBS ..................................................19 Chapter 4 Is DBS Right for You? ...........
MBAnderson
in
Cure Parkinson's
3 years ago
DBS for Parkinsons
Need a little info on the DBS surgery for Parkinson’s. Doc says our daughter has reached the limit for the Sinemet dosage and is beginning g to show signs of needing more help. The only thing left is DBS. She’s not worried about the actual surgery but the cost since her insurance won’t cover very much
Need a little info on the DBS surgery for Parkinson’s. Doc says our daughter has reached the limit for the Sinemet dosage and is beginning g to show signs of needing more help. The only thing left is DBS. She’s not worried about the actual surgery but the cost since her insurance won’t cover very much
Williemom
in
Positive Wellbeing During Self-Isolation
3 years ago
Dbs lottery?
Dbs lottery
Dbs lottery
Abepark2013
in
Cure Parkinson's
3 years ago
DBS lottery
Whilst I’ve read dozens of posters extolling the virtues of DBS here on the site and have witnessed many stories on YouTube similarly telling of good things, the PWP that I know personally who’ve had it haven’t been so encouraging. 😕 Guy 1 was hoping to reduce his meds but has ended up taking the
Whilst I’ve read dozens of posters extolling the virtues of DBS here on the site and have witnessed many stories on YouTube similarly telling of good things, the PWP that I know personally who’ve had it haven’t been so encouraging. 😕 Guy 1 was hoping to reduce his meds but has ended up taking the
jeeves19
in
Cure Parkinson's
3 years ago
Stress triggering meningitis
What are your thoughts on stress being a trigger for a viral infection and triggering viral meningitis and M.E? Do you think stress plays a contributing factor?
What are your thoughts on stress being a trigger for a viral infection and triggering viral meningitis and M.E? Do you think stress plays a contributing factor?
Sunny308
in
Meningitis Now
3 years ago
Chronic Shingles & Hashi/Hypo
Anyone else get Shingles everytime their TSH rises due to Hashi’s & it’s time for an increase in Levo.mg’s? This has been my pattern for a year now. First round was face/neck second was armpits. Both times bilateral. Shingles vaccine has not been an option for me because I can’t go long enough in between
Anyone else get Shingles everytime their TSH rises due to Hashi’s & it’s time for an increase in Levo.mg’s? This has been my pattern for a year now. First round was face/neck second was armpits. Both times bilateral. Shingles vaccine has not been an option for me because I can’t go long enough in between
badgenes
in
Thyroid UK
3 years ago
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