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Pelvic Organ Prolapse Can You Advise, Please? Monday Hospital Visit (and would prefer to avoid surgery)
Hello I have had a problem with 'everything' coming south for a while! A little background: I have had intermittent waves of pelvic pain (which come centrally to just below my navel) for 20+ years and have had investigations, scans, a D and C but nothing found except a large fibroid which should have
Hello I have had a problem with 'everything' coming south for a while! A little background: I have had intermittent waves of pelvic pain (which come centrally to just below my navel) for 20+ years and have had investigations, scans, a D and C but nothing found except a large fibroid which should have
Rostom
in
Pelvic Pain Support Network
4 years ago
Hard prostate
I've given myself a couple of DRE's. On the first one, nothing felt unusual. On the second I noticed it felt hard all over. I read that this is an indicator of PCa. Other symptoms = rather sudden ED, inability to orgasm, minor discomfort in perineum area (which could be imaginary) when sitting on hard
I've given myself a couple of DRE's. On the first one, nothing felt unusual. On the second I noticed it felt hard all over. I read that this is an indicator of PCa. Other symptoms = rather sudden ED, inability to orgasm, minor discomfort in perineum area (which could be imaginary) when sitting on hard
jfw657
in
Advanced Prostate Cancer
4 years ago
New Mechanism of Pain Control Revealed - pnorepinephrine. Locus coeruleus.
New Mechanism of Pain Control Revealed - norepinephrine. Locus coeruleus. https://neurosciencenews.com/lc-neurons-pain-17325/ Summary: Stimulating noradrenergic neurons in the locus coeruleus that carry signals from the brain down the spinal dorsal horn activates astrocytes. The astrocyte activation
New Mechanism of Pain Control Revealed - norepinephrine. Locus coeruleus. https://neurosciencenews.com/lc-neurons-pain-17325/ Summary: Stimulating noradrenergic neurons in the locus coeruleus that carry signals from the brain down the spinal dorsal horn activates astrocytes. The astrocyte activation
aspergerian
in
Cure Parkinson's
4 years ago
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Cystoscopy and hydrodistention
Has anyone had a cystoscope and hydrodistention (stretching of bladder) whilst under general anaesthetic? I have stage 4 endometriosis and now suffer with pain every day. I’m more terrified of the pelvic pain I’m going to experience afterwards as it’s sure to aggravate the surrounding areas than I am
Has anyone had a cystoscope and hydrodistention (stretching of bladder) whilst under general anaesthetic? I have stage 4 endometriosis and now suffer with pain every day. I’m more terrified of the pelvic pain I’m going to experience afterwards as it’s sure to aggravate the surrounding areas than I am
Lily1986
in
Endometriosis UK
4 years ago
BAT, dutasteride, and my search for truth, Part 1 of 2
I have received many helpful comments on my queries about BAT and dutasteride. Overall, the evidence favors continuing dutasteride during BAT (Nalakrats opined “I would use to defend against DHT, which would be increased. And I would watch E2, and not let it get out of the 20's.”) But I have trouble
I have received many helpful comments on my queries about BAT and dutasteride. Overall, the evidence favors continuing dutasteride during BAT (Nalakrats opined “I would use to defend against DHT, which would be increased. And I would watch E2, and not let it get out of the 20's.”) But I have trouble
cigafred
in
Advanced Prostate Cancer
4 years ago
BAT, dutasteride, and my search for truth, Part 2 of 2
I believe it was Patrick who said “When 5alpha-reductase acts on T to produce DHT, this kicks off production of an enzyme to clear DHT from the cell. DHT has a very narrow window in which to promote growth. One of the metabolites of DHT is an estrogen - 3beta-adiol - which happens to be the natural
I believe it was Patrick who said “When 5alpha-reductase acts on T to produce DHT, this kicks off production of an enzyme to clear DHT from the cell. DHT has a very narrow window in which to promote growth. One of the metabolites of DHT is an estrogen - 3beta-adiol - which happens to be the natural
cigafred
in
Advanced Prostate Cancer
4 years ago
First pregnancy & MMC
Hi all. Although I have been a member of the forum for a few months, this is my first post and I just wanted to say how helpful it has been to me over the past few weeks. My partner and I have been trying to conceive our first child for over 2 years - been through all the tests with the NHS and had
Hi all. Although I have been a member of the forum for a few months, this is my first post and I just wanted to say how helpful it has been to me over the past few weeks. My partner and I have been trying to conceive our first child for over 2 years - been through all the tests with the NHS and had
Party_Weasel
in
Pregnancy and Parenting Support
4 years ago
Good news following mediastinal lymph node query
I thought I would post some good news. Husband's latest CT scan (regular scan) shows the mediastinal lymphadenopathy 'resolved' and nothing new showed up. PSA at 1. He has no pain, just the awful mood swings/depression from the ADT, so lots to be thankful for. And ..... there is a covid vaccine on
I thought I would post some good news. Husband's latest CT scan (regular scan) shows the mediastinal lymphadenopathy 'resolved' and nothing new showed up. PSA at 1. He has no pain, just the awful mood swings/depression from the ADT, so lots to be thankful for. And ..... there is a covid vaccine on
Proflac
in
Advanced Prostate Cancer
4 years ago
Amitripyline
Has anyone ever taken Amitripyline for spasms in the esophagus? I am new—-this is my first post. I have been having severe pain in between my breast that radiates through my back —last about five to ten minutes then totally no pain at all. It happens a lot after rushing and being stresses and after
Has anyone ever taken Amitripyline for spasms in the esophagus? I am new—-this is my first post. I have been having severe pain in between my breast that radiates through my back —last about five to ten minutes then totally no pain at all. It happens a lot after rushing and being stresses and after
Fraunfelter
in
Pain Concern
4 years ago
Gallbladder polyp?
Does anyone have experience of gallbladder polyps? Mine has been found after routine ultrasound? Many thanks
Does anyone have experience of gallbladder polyps? Mine has been found after routine ultrasound? Many thanks
Baggiebird67
in
IBS Network
4 years ago
Update on Jim Nov. 2020
Jim had labs, CT, and a bone scan on Monday. It’s been a bit of a rollercoaster. Labs good 😊 except for PSA-Up to 49.6. 🙁 Bone scan and CT showed decrease in uptake in lesions of the ribs, pelvis, and lower thoracic vertebra 😊 and new uptake in multiple upper thoracic vertebra. 🙁 CT showed that
Jim had labs, CT, and a bone scan on Monday. It’s been a bit of a rollercoaster. Labs good 😊 except for PSA-Up to 49.6. 🙁 Bone scan and CT showed decrease in uptake in lesions of the ribs, pelvis, and lower thoracic vertebra 😊 and new uptake in multiple upper thoracic vertebra. 🙁 CT showed that
GrizzlyMama
in
Advanced Prostate Cancer
4 years ago
Update: A choice between 2 clinical trials as of yesterday afternoon. 1. AMG 509 and 2. Cocktail of 4 immunotherapy drugs.
There are 2 programs for which I meet the broad criteria. Assuming the labs and images needed close to the start date meet their expectations, I can start the AMG 509 program at Penn on December 14th. I met with the Jefferson team yesterday and they are genuinely excited about the antibody in this study
There are 2 programs for which I meet the broad criteria. Assuming the labs and images needed close to the start date meet their expectations, I can start the AMG 509 program at Penn on December 14th. I met with the Jefferson team yesterday and they are genuinely excited about the antibody in this study
Philly13
in
Advanced Prostate Cancer
4 years ago
How a lung injury study helped inspire new COVID-19 drug trials.
When Anna Greka, an institute member at the Broad Institute of MIT and Harvard and a physician at Brigham and Women’s Hospital, volunteered to help care for patients with COVID-19 at the peak of Boston’s springtime surge, she saw first-hand the severity of lung damage in seriously ill patients — and
When Anna Greka, an institute member at the Broad Institute of MIT and Harvard and a physician at Brigham and Women’s Hospital, volunteered to help care for patients with COVID-19 at the peak of Boston’s springtime surge, she saw first-hand the severity of lung damage in seriously ill patients — and
2greys
in
Lung Conditions Community Forum
4 years ago
Parasite Infection Discovery Could Assist Mental Health Treatments . T.gondii. Norepinephrine.
Parasite Infection Discovery Could Assist Mental Health Treatments . T.gondii. Norepinephrine. Summary: Behavioral changes in those with T.gondii infection could be linked to lower levels of norepinephrine. Norepinephrine also controls inflammation. Both neuroinflammation and norepinephrine are associated
Parasite Infection Discovery Could Assist Mental Health Treatments . T.gondii. Norepinephrine. Summary: Behavioral changes in those with T.gondii infection could be linked to lower levels of norepinephrine. Norepinephrine also controls inflammation. Both neuroinflammation and norepinephrine are associated
aspergerian13
in
Cure Parkinson's
4 years ago
Management of moderate to severe incontinence – no AUS 800 possible but an ileal conduit diversion did the trick
A recent, comprehensive post at the Fight Prostate Cancer (FPC) hub of HU about the Artificial Urinary Sphincter prompted me to update my husband journey. That post made me think a description of my husband’s incontinence experience and his long journey to a solution might be similarly helpful to some
A recent, comprehensive post at the Fight Prostate Cancer (FPC) hub of HU about the Artificial Urinary Sphincter prompted me to update my husband journey. That post made me think a description of my husband’s incontinence experience and his long journey to a solution might be similarly helpful to some
marnieg46
in
Advanced Prostate Cancer
4 years ago
Title :Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer
With all the interest in my last post I thought some might be interested in this: https://www.cureitt.com/trialdetails?nctid=NCT03123978 Maybe someone out there could explain the difference between niclosamide and Fenbendazole, they are both used for deworming dogs.
With all the interest in my last post I thought some might be interested in this: https://www.cureitt.com/trialdetails?nctid=NCT03123978 Maybe someone out there could explain the difference between niclosamide and Fenbendazole, they are both used for deworming dogs.
Magnus1964
in
Advanced Prostate Cancer
4 years ago
Ibs
Hi I have suffered 9 years with ibs pain.. Yesterday I was diagnosed with ibs and today I got spasmonal to help me..
Hi I have suffered 9 years with ibs pain.. Yesterday I was diagnosed with ibs and today I got spasmonal to help me..
paining
in
IBS Network
4 years ago
New. Post prostatectomy PFM therapy, sling,
Hello! I’m new to this community. I had a RALP (Robot Assisted Laparoscopic Prostatectomy) 11 months ago. I had a Gleason 8 prostate cancer. That problem was solved, my PSA has been zero since then. However, I was left with significant urinary incontinence. I have been doing Kegels ever since the surgery
Hello! I’m new to this community. I had a RALP (Robot Assisted Laparoscopic Prostatectomy) 11 months ago. I had a Gleason 8 prostate cancer. That problem was solved, my PSA has been zero since then. However, I was left with significant urinary incontinence. I have been doing Kegels ever since the surgery
Iupiter
in
Advanced Prostate Cancer
4 years ago
Post weight loss surgery
Hey guys... I’m 34, m and I have lost 284 lbs naturally over the last 4 years. I have had abdominoplasty and am looking for some feedback on my other areas on my body... specifically chest, back and thighs. I would love to chat with someone around my age “ish” who has some knowledge, insight or personal
Hey guys... I’m 34, m and I have lost 284 lbs naturally over the last 4 years. I have had abdominoplasty and am looking for some feedback on my other areas on my body... specifically chest, back and thighs. I would love to chat with someone around my age “ish” who has some knowledge, insight or personal
Hidden
in
Sensitive Issues for Men
4 years ago
Articles on the status of immunotherapy in PCa and infomation about AMG-160-BiTE therapy.
Hello FPC members, I found an interesting article on the status of immunotherapies in PCa which I found mentally and spiritually stimulating. I believe when you read this article, you will be surprised at all the studies that are ongoing for immunotherapy drugs alone or in combo. It includes tables
Hello FPC members, I found an interesting article on the status of immunotherapies in PCa which I found mentally and spiritually stimulating. I believe when you read this article, you will be surprised at all the studies that are ongoing for immunotherapy drugs alone or in combo. It includes tables
NPfisherman
in
Fight Prostate Cancer
4 years ago
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