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Orchiectomy
Anyone in this foum had an actual Orchiectomy?I have been thinking about having this done. I'm 78 and I'm or hormone therapy which in chemical castration (Orchiectomy)so why not do the actual thing. I'm not going to have any more children at my age and I will probably be on hormone therapy for the next
Anyone in this foum had an actual Orchiectomy?I have been thinking about having this done. I'm 78 and I'm or hormone therapy which in chemical castration (Orchiectomy)so why not do the actual thing. I'm not going to have any more children at my age and I will probably be on hormone therapy for the next
woppaginny
in
Advanced Prostate Cancer
9 months ago
Cardiac Ablation Looks Successful!
I was diagnosed with Paroxysmal Afib in April of 2022. During my annual physical my PCP heard what he thought was a murmur, and called in a consult. After testing the afib was confirmed. I never noticed it, but started monitoring with a smartwatch and began to feel the episodes as they progressed. This
I was diagnosed with Paroxysmal Afib in April of 2022. During my annual physical my PCP heard what he thought was a murmur, and called in a consult. After testing the afib was confirmed. I never noticed it, but started monitoring with a smartwatch and began to feel the episodes as they progressed. This
Row2k
in
AF Association
9 months ago
Senolytics - “senolytic” drugs, dasatinib (D) and quercetin (Q) disapointing results in small test- Peter Attia
January 13, 2024 COGNITIVE HEALTH & NEURODEGENERATIVE DISEASE Targeting senescent cells for cognitive health With the recent publication of the first clinical trial of senolytics for AD treatment, popular interest in these drugs has swelled, but is the excitement justified? PETER ATTIA
January 13, 2024 COGNITIVE HEALTH & NEURODEGENERATIVE DISEASE Targeting senescent cells for cognitive health With the recent publication of the first clinical trial of senolytics for AD treatment, popular interest in these drugs has swelled, but is the excitement justified? PETER ATTIA
Scout4answers
in
Fight Prostate Cancer
4 months ago
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OCD Institute - Houston
My adult son was recently referred to the OCD Institute in Houston for residential treatment. Has anyone had success there or can anyone share their experience there? He has been in outpatient treatment since the beginning of January and so far it is not working well. We are looking for any help we can
My adult son was recently referred to the OCD Institute in Houston for residential treatment. Has anyone had success there or can anyone share their experience there? He has been in outpatient treatment since the beginning of January and so far it is not working well. We are looking for any help we can
BrooksideBliss
in
My OCD Community
2 months ago
Lightheaded after AF episode
I was diagnosed with Atrial Fibrillation in October 2021 and prescribed Edoxaban. Fortunately I have only been experiencing AF edisodes about once a month but when I do I find it very frightening. It’s probably the effect of passing so much urine but I find after the episode my blood pressure drops very
I was diagnosed with Atrial Fibrillation in October 2021 and prescribed Edoxaban. Fortunately I have only been experiencing AF edisodes about once a month but when I do I find it very frightening. It’s probably the effect of passing so much urine but I find after the episode my blood pressure drops very
Jomaur
in
Atrial Fibrillation Support
9 months ago
slow release liothyronine
Like many people on here I miss the wise opinion and knowledge of Diogenes enormously. I know he was working on the formulation of a slow release liothyronine which was in clinical trial. Does anyone have an update on this? is it any closer? In the meantime I am tempted to try sustained release compounded
Like many people on here I miss the wise opinion and knowledge of Diogenes enormously. I know he was working on the formulation of a slow release liothyronine which was in clinical trial. Does anyone have an update on this? is it any closer? In the meantime I am tempted to try sustained release compounded
Mollyfan
in
Thyroid UK
2 months ago
Smell Training (Olfactory Training)
Smell Training (Olfactory Training)
March 18, 2024
This post is about Smell Training and is building on an earlier HU post “Olfactory enrichment improves olfactory ability in humans with olfactory loss due to Parkinson’s”
https://healthunlocked.com/cure-parkinsons/posts/150588869/olfactory-enrichment-improves-olfactory-ability-in-humans-with-olfactory-loss-due-to-parkinson-s
Smell Training (Olfactory Training)
March 18, 2024
This post is about Smell Training and is building on an earlier HU post “Olfactory enrichment improves olfactory ability in humans with olfactory loss due to Parkinson’s”
https://healthunlocked.com/cure-parkinsons/posts/150588869/olfactory-enrichment-improves-olfactory-ability-in-humans-with-olfactory-loss-due-to-parkinson-s
Bolt_Upright
in
Cure Parkinson's
2 months ago
Seeking anyone familiar with aggressive small cell neuroendocrine prostate cancer and/or with lurbinectedin as 2nd line chemotherapy.
A needle biopsy Oct 15, 2023 revealed that at least some of my metastatic prostate cancer in a lymph node had mutated to an aggressive small cell neuroendocrine prostate cancer. (notable for CDK N1B, RB1, Tp53 mutations. MSS, TMB low) I had 4 cycles of carboplatin/etoposide chemotherapy, which ended
A needle biopsy Oct 15, 2023 revealed that at least some of my metastatic prostate cancer in a lymph node had mutated to an aggressive small cell neuroendocrine prostate cancer. (notable for CDK N1B, RB1, Tp53 mutations. MSS, TMB low) I had 4 cycles of carboplatin/etoposide chemotherapy, which ended
silver5
in
Advanced Prostate Cancer
2 months ago
Weighing the pros and possible risks of treatment holiday.
I am looking for reliable articles (not too scientific please). We will be discussing w oncologist this week and again with his clinical trial people next month. My husband's only treatment has been 1st & 2nd generation hormone therapy (Eligard & Darolutamide) for 20 months. He reached >.1 nadar
I am looking for reliable articles (not too scientific please). We will be discussing w oncologist this week and again with his clinical trial people next month. My husband's only treatment has been 1st & 2nd generation hormone therapy (Eligard & Darolutamide) for 20 months. He reached >.1 nadar
Decktime
in
Advanced Prostate Cancer
2 months ago
NSAIDS and Afib.
After a concussion last January, I started taking Naproxen regularly. AND I started having break-thru Afib episodes. My docs KNEw I was taking this but said nothing. My cardiologist who knows I have Afib said nothing. So, I read about it and yep, people with Afib are cautioned NOT to take NSAIDS!!!
After a concussion last January, I started taking Naproxen regularly. AND I started having break-thru Afib episodes. My docs KNEw I was taking this but said nothing. My cardiologist who knows I have Afib said nothing. So, I read about it and yep, people with Afib are cautioned NOT to take NSAIDS!!!
Missyanne
in
AF Association
9 months ago
Webinar:Do magnifying intraocular lenses work for people with macular disease?
Magnifying lenses, which are implanted are available to help those with macular disease see better. But, no trials have been done to prove how useful they are or who they are most suitable for. Dr Julie Silvestri from Royal Hospitals, Belfast, will be joining us for our first webinar of the month to
Magnifying lenses, which are implanted are available to help those with macular disease see better. But, no trials have been done to prove how useful they are or who they are most suitable for. Dr Julie Silvestri from Royal Hospitals, Belfast, will be joining us for our first webinar of the month to
Carol_MacularSociety
Partner
in
Macular Society
2 months ago
Chemo or clinical trial?
Am scheduled for bone biopsy of met(s) from my hip tomorrow. Stopped Pluvicto after #3 due to rising PSA and progression. Hoping to get next gen. sequencing from biopsy sample and (maybe) functional testing. But, it's going to take some time to get results and I feel I can't wait. Pain has been getting
Am scheduled for bone biopsy of met(s) from my hip tomorrow. Stopped Pluvicto after #3 due to rising PSA and progression. Hoping to get next gen. sequencing from biopsy sample and (maybe) functional testing. But, it's going to take some time to get results and I feel I can't wait. Pain has been getting
rsgdmd
in
Advanced Prostate Cancer
2 months ago
How effective is cardioversion for Persistent AFib?
Thank you to all those who have recently posted replies to my recent question ‘Has anyone had problems with Flecainide not working?’. Your answers have clarified the some of the options to discuss with my cardiologist, hopefully in a couple of days. I propose to gradually stop taking Flecainide but
Thank you to all those who have recently posted replies to my recent question ‘Has anyone had problems with Flecainide not working?’. Your answers have clarified the some of the options to discuss with my cardiologist, hopefully in a couple of days. I propose to gradually stop taking Flecainide but
golfwatcher
in
AF Association
9 months ago
Saxon clinical trial
Hello all, I was recently enrolled in the Saxon clinical trial combining Xofigo with SBRT. Is anyone else in that trial? Diagnosed with prostate Cancer July 2014, Gleason 7 (4+3) in 6 of 12 . After Radiation treatments my PSA was undetectable until July 2019. It rose to 3.9 in January 2020
Hello all, I was recently enrolled in the Saxon clinical trial combining Xofigo with SBRT. Is anyone else in that trial? Diagnosed with prostate Cancer July 2014, Gleason 7 (4+3) in 6 of 12 . After Radiation treatments my PSA was undetectable until July 2019. It rose to 3.9 in January 2020
58Willys
in
Advanced Prostate Cancer
2 months ago
The Importance of Peer-Review
Even renowned oncologists can fall in love with their data. It takes the impartial analysis of an outside expert to see the confirmation bias that may be blinding the lead investigator of a Phase 3 clinical trial. Although Phase 3 trials are Level 1 evidence, they still must be graded by outside experts
Even renowned oncologists can fall in love with their data. It takes the impartial analysis of an outside expert to see the confirmation bias that may be blinding the lead investigator of a Phase 3 clinical trial. Although Phase 3 trials are Level 1 evidence, they still must be graded by outside experts
Tall_Allen
in
Advanced Prostate Cancer
2 months ago
How long on Entresto
I would like to ask what’s the longest anyone on this post has been on Entresto. My cardiologist has patients who started on it back when the clinical trials began in 2015 and doing quite well.
I would like to ask what’s the longest anyone on this post has been on Entresto. My cardiologist has patients who started on it back when the clinical trials began in 2015 and doing quite well.
am1875
in
British Heart Foundation
2 months ago
Upcoming TTALC Workshop 3/23/24
Did you know? Clinical trials provide new treatment options, especially if existing treatments have not worked. You may also receive more attentive care in a clinical trial study because it requires close observation and follow-up from a team of doctors. Join our live interactive workshop to learn more
Did you know? Clinical trials provide new treatment options, especially if existing treatments have not worked. You may also receive more attentive care in a clinical trial study because it requires close observation and follow-up from a team of doctors. Join our live interactive workshop to learn more
AllysonBlueFaery
Community Ambassador
in
Blue Faery Liver Cancer
2 months ago
Clinical Trial Starts Today
Morning folks, Sitting in clinic at Sarah Cannon Research Institute in Nashville getting my first dose of Phase 1 trial of a Xencor drug called XmAb808, which is an antibody that binds to tumor cells and immune cells called T cells. Baseline scans looked decent and all systems are go. Really blessed
Morning folks, Sitting in clinic at Sarah Cannon Research Institute in Nashville getting my first dose of Phase 1 trial of a Xencor drug called XmAb808, which is an antibody that binds to tumor cells and immune cells called T cells. Baseline scans looked decent and all systems are go. Really blessed
Pmann
in
Advanced Prostate Cancer
2 months ago
Experiences with Metoprolol
I was dx with Parosyximal Afib in 2019 and, after the customary course of starting with a beta blocker - Metoprolol, which didn't work - and then adding flecainide which did help but not prevent breakthrough episodes, had an ablation on March 16 of 2022. After the ablation, I weaned off of the metoprolol
I was dx with Parosyximal Afib in 2019 and, after the customary course of starting with a beta blocker - Metoprolol, which didn't work - and then adding flecainide which did help but not prevent breakthrough episodes, had an ablation on March 16 of 2022. After the ablation, I weaned off of the metoprolol
willec49
in
AF Association
9 months ago
Metoprolol or not
I was dx with Parosyximal Afib in 2019 and, after the customary course of starting with a beta blocker - Metoprolol, which didn't work - and then adding flecainide which did help but not prevent breakthrough episodes, had an ablation on March 16 of 2022. After the ablation, I weaned off of the metoprolol
I was dx with Parosyximal Afib in 2019 and, after the customary course of starting with a beta blocker - Metoprolol, which didn't work - and then adding flecainide which did help but not prevent breakthrough episodes, had an ablation on March 16 of 2022. After the ablation, I weaned off of the metoprolol
willec49
in
Arrhythmia Alliance
9 months ago
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