New treatment : 2 weeks ago I had liver... - SHARE Metastatic ...

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JulieB76 profile image
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2 weeks ago I had liver ablation to remove 3 tumors on my liver. 2 were responding to treatment (anastrozole and kisqali for HER2 neg) and 1 was not. Surgery went well. Biopsy showed that the growing tumor was triple negative. Seemingly the other 2 (breast and hip met) are still HER2 negative. Anyone being treated for both? Also considering a clinical trial for the triple that they found, although there is no known tumor. Thoughts?

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JulieB76
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Trissh profile image
Trissh

Good morning Julie. I can't help with your question but I am curious about your liver ablation. Can you provide more context? My onc has said that is not something she would include in treatment unless I feel very strongly about it. Then we can investigate. What was your doctor's reasoning and what kind of ablation did you have?

Bettybuckets profile image
Bettybuckets in reply to Trissh

Me too very curious and hope you will expand on the reasoning and safety vs controlling with chemo.

Elle713 profile image
Elle713

I have just been diagnosed with tumors in my liver. Everyone told me I was having muscle spasms until my recent PET. May I ask if you feel pain from liver - what symptoms and what do you do?

Trissh profile image
Trissh in reply to Elle713

Hi Elle, Sorry but I just saw this message! I had no symptoms at all connected to liver meds. They were quite large 5-6 cm. They were discovered after an MRI to determine why my thigh was so painful when I put any weight on it. I was on Ibrance and Letrozole for almost 2 years and they shrunk by at least half. I am now on a clinical trial because I have the PIK3CA mutation and Inavolisib was available with another ER degrader at my cancer center so I chose to do that. Stable for first 5 months so far. --Trish

Trissh profile image
Trissh in reply to Trissh

*liver mets

JulieB76 profile image
JulieB76

The treatment was working with 2 tumors, but the 3rd was growing. The biopsy revealed it had mutated. As far as we know, the original breast tumor and hip tumor will still respond to previous hormone meds. Not sure exactly what will be used since triple negative has been discovered, but probably immunotherapy.

Coddfish profile image
Coddfish

I have metastatic TNBC with initially 1 and later a 2nd tumour in the liver. I have had 2 microwave ablation procedures, one in Dec 22 and the 2nd in Feb 24. I have also had immunotherapy - Pembrolizumab- which is only applicable if your TNBC met is PD-L1 positive.

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