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Clarity Update: Complete response in first patient ever treated with 2 doses of Cu-67 SAR-bisPSMA at 8GBq
Highlights A complete response, based on Response Evaluation Criteria In Solid Tumours (RECIST v1.1) assessment, has been reported from the first patient with metastatic castrate-resistant prostate cancer (mCRPC) to ever receive two cycles of Clarity’s 67Cu-SAR-bisPSMA at the 8GBq dose level. The patient
Highlights A complete response, based on Response Evaluation Criteria In Solid Tumours (RECIST v1.1) assessment, has been reported from the first patient with metastatic castrate-resistant prostate cancer (mCRPC) to ever receive two cycles of Clarity’s 67Cu-SAR-bisPSMA at the 8GBq dose level. The patient
God_Loves_Me
in
Advanced Prostate Cancer
3 days ago
Should go into the OMAHA2a ODM-208 (MK-5684-004): phase 3 trial?
I had my 3 monthly OC visit last week. Blood test is showing 0.3 up from 0.15 six weeks ago. MO is suggesting that I should go into the ODM-208 (MK-5684): phase 3 trial if PSA rises above 1.0. PSA of 1.0 or above is a entry requirement for the trial, presumable to be sure that my current treatment
I had my 3 monthly OC visit last week. Blood test is showing 0.3 up from 0.15 six weeks ago. MO is suggesting that I should go into the ODM-208 (MK-5684): phase 3 trial if PSA rises above 1.0. PSA of 1.0 or above is a entry requirement for the trial, presumable to be sure that my current treatment
LakeT
in
Advanced Prostate Cancer
4 days ago
Had Pet Scan, PSA rising 0.77 Found Liver Metastases, Am I a dead man? What can I do?
Going for MRI and Biopsy What can I do?
Going for MRI and Biopsy What can I do?
Shorehousejam
in
Advanced Prostate Cancer
4 days ago
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rising PSA and 'light' advancement of mets in hip bones. Diagnosed stage 4 in March 2021.
Greetings! My husband was diagnosed with stage 4 prostate cancer in March 2021. ADT dropped the PSA quite a bit. We started seeing Dr. George at Duke March of 2023 and he had my husband on a round of docetaxel. After that the many bone mets and some on lungs 'disappeared'. Now it looks like they
Greetings! My husband was diagnosed with stage 4 prostate cancer in March 2021. ADT dropped the PSA quite a bit. We started seeing Dr. George at Duke March of 2023 and he had my husband on a round of docetaxel. After that the many bone mets and some on lungs 'disappeared'. Now it looks like they
Newdiag-NC
in
Advanced Prostate Cancer
4 days ago
Theraglass
Due to start Gemcitabine in June for 2nd recurrence since surgery. Finished 7 months of caylex/ carbo in November. Really enjoying past 5 months of no treatment ( first time with no treatment in 3yrs). Not feeling ready to start again! Anyone else going through gemcitabine on its own and what your symptoms
Due to start Gemcitabine in June for 2nd recurrence since surgery. Finished 7 months of caylex/ carbo in November. Really enjoying past 5 months of no treatment ( first time with no treatment in 3yrs). Not feeling ready to start again! Anyone else going through gemcitabine on its own and what your symptoms
Theraglass
in
My Ovacome
5 days ago
Treatment Recommendation for father with advanced PCA to regional lymph nodes
Hi All, I was hoping for some feedback on the treatment schedule advised for my father. All the details for his diagnosis are in my bio. We met with the radio oncologist last week and he suggested the following 1. Start cosudex tablets now for 28 days and then stop 2. Start Zoladex injection within
Hi All, I was hoping for some feedback on the treatment schedule advised for my father. All the details for his diagnosis are in my bio. We met with the radio oncologist last week and he suggested the following 1. Start cosudex tablets now for 28 days and then stop 2. Start Zoladex injection within
MissMel2024
in
Advanced Prostate Cancer
5 days ago
Watching and waiting
My 78 year old husband was diagnosed with prostate cancer Gleason 8 two years ago. ( Urologist noticed a very slight rise in psa and located a tumor after dre. Biopsy showed cancerous cells in Only in three cores. Bone scan clean. Subsequently had 28 rounds of radiation and three rounds of CyberKnife
My 78 year old husband was diagnosed with prostate cancer Gleason 8 two years ago. ( Urologist noticed a very slight rise in psa and located a tumor after dre. Biopsy showed cancerous cells in Only in three cores. Bone scan clean. Subsequently had 28 rounds of radiation and three rounds of CyberKnife
Pastaking
in
Advanced Prostate Cancer
6 days ago
Nano-MRI outduels PSMA-PET/CT for prostate cancer
https://www.auntminnie.com/clinical-news/molecular-imaging/article/15627757/nano-mri-outduels-psma-pet-ct-for-prostate-cancer Hopefully one day will be available to anybody
https://www.auntminnie.com/clinical-news/molecular-imaging/article/15627757/nano-mri-outduels-psma-pet-ct-for-prostate-cancer Hopefully one day will be available to anybody
FMOH_N
in
Advanced Prostate Cancer
6 days ago
Following SOC here in BC Canada
I am currently at the CRPC stage of my disease. About 7 years since diagnosis. Started with ADT and Docetaxel. Was able to be castrate sensitive for 4.5 years. Tried to add Abiraterone and it failed after a couple of months. Had Radium 223 and it was okay but did nothing to the PSA. Cancer kept progressing
I am currently at the CRPC stage of my disease. About 7 years since diagnosis. Started with ADT and Docetaxel. Was able to be castrate sensitive for 4.5 years. Tried to add Abiraterone and it failed after a couple of months. Had Radium 223 and it was okay but did nothing to the PSA. Cancer kept progressing
Islandboy2021
in
Advanced Prostate Cancer
6 days ago
Getting Lutetium 177 PSMA in Vancouver?
I recently attended a prostate cancer support group meeting in metro Vancouver where a radiation medicine specialist talked about options for prostate cancer theranostics in our province of British Columbia. I was surprised to learn that Americans can come up here and get Lutetium 177 PSMA treatments
I recently attended a prostate cancer support group meeting in metro Vancouver where a radiation medicine specialist talked about options for prostate cancer theranostics in our province of British Columbia. I was surprised to learn that Americans can come up here and get Lutetium 177 PSMA treatments
Wassersug
in
Advanced Prostate Cancer
7 days ago
After Pluvicto #6 results
Finished my 6th and final Pluvicto and am now getting lab results. I see that somehow I neglected to put results after #5 -- may have been distracted by doctors freaking out that my kidney function was going down and my calcium shot up. My nuclear medicine doc made a judgement call to give me a full
Finished my 6th and final Pluvicto and am now getting lab results. I see that somehow I neglected to put results after #5 -- may have been distracted by doctors freaking out that my kidney function was going down and my calcium shot up. My nuclear medicine doc made a judgement call to give me a full
Miccoman
in
Advanced Prostate Cancer
7 days ago
PCA and Marrow Replacing Lesions
It is my understanding that PCa bone mets are not normally marrow replacing. I've had bone mets for about 3 years. Recently some large bones have been diagnosed with marrow replacing lesions. I'm wondering how common this actually is with prostate cancer bone mets?
It is my understanding that PCa bone mets are not normally marrow replacing. I've had bone mets for about 3 years. Recently some large bones have been diagnosed with marrow replacing lesions. I'm wondering how common this actually is with prostate cancer bone mets?
milehigh
in
Advanced Prostate Cancer
7 days ago
Active Surveillance?
Hello everyone, I am 72 and have been on active surveillance for prostate cancer since I was diagnosed in August 2021 but probably had it prior to my first MRI in 2020. I have had 2 biopsies and 5 MRI's and countless PSA tests. First bx showed 3 cores at 3+3 and 2 cores suspicious, confirmatory bx a
Hello everyone, I am 72 and have been on active surveillance for prostate cancer since I was diagnosed in August 2021 but probably had it prior to my first MRI in 2020. I have had 2 biopsies and 5 MRI's and countless PSA tests. First bx showed 3 cores at 3+3 and 2 cores suspicious, confirmatory bx a
ironmanburg
in
Prostate Cancer Network
7 days ago
MRI prior to Radiation Treatments + HT
My PSA has risen over nearly 5.5 years since my prostatectomy from Undetectable to 0.3. I was referred to an RO who, after reviewing my test results and prior history, indicated that there were some "cells left behind" near the prostate bed, even though they tried to get at them unsuccessfully during
My PSA has risen over nearly 5.5 years since my prostatectomy from Undetectable to 0.3. I was referred to an RO who, after reviewing my test results and prior history, indicated that there were some "cells left behind" near the prostate bed, even though they tried to get at them unsuccessfully during
brilliant17
in
Advanced Prostate Cancer
8 days ago
Starting the journey Interested in comments Gleason 5+4 Met to Lymph and Maybe ribs
I have just started this journey, and am deciding on treatments now. 60 years young with a Gleason 5+4 PSA hovering around 7. My PSMA PET showed one lymph near pelvis for sure, and possibly a rib neat top on left side. My medical oncologist ordered a bone scan, which showed nothing on the left side
I have just started this journey, and am deciding on treatments now. 60 years young with a Gleason 5+4 PSA hovering around 7. My PSMA PET showed one lymph near pelvis for sure, and possibly a rib neat top on left side. My medical oncologist ordered a bone scan, which showed nothing on the left side
Saladman50
in
Advanced Prostate Cancer
8 days ago
Waiting for Mr. T
I had an interesting development this week in my PCa journey. I went in for my quarterly hospital visit, which would normally include blood tests, meeting with my medical oncologist, and my last 3-month injection of Eligard. Blood tests were great, PSA and testosterone still undetectable. My MO decided
I had an interesting development this week in my PCa journey. I went in for my quarterly hospital visit, which would normally include blood tests, meeting with my medical oncologist, and my last 3-month injection of Eligard. Blood tests were great, PSA and testosterone still undetectable. My MO decided
Atdabeach
in
Advanced Prostate Cancer
8 days ago
Update recent PSMA
Docs did it to me again with the usual bad news. Uptake in new lymph node locations in pelvis. the radiotherapy failed, and preclude more treatment on new nodal areas. (according to Docs.) So expect to add to ADT, abi or enza or darolutamide in a short while, with PSA going up on a fast double.
Docs did it to me again with the usual bad news. Uptake in new lymph node locations in pelvis. the radiotherapy failed, and preclude more treatment on new nodal areas. (according to Docs.) So expect to add to ADT, abi or enza or darolutamide in a short while, with PSA going up on a fast double.
kainasar
in
Advanced Prostate Cancer
8 days ago
Caelyx.... successful outcomes????
I have just finished six rounds of monthly Caelyx only. This is my fourth line of chemo ie. Third recurrence.While my CA125 didn't go down to normal level it was decreasing steadily until I got my results yesterday for the fifth round . It had risen to 257 from 189. I was really upset with this. I feel
I have just finished six rounds of monthly Caelyx only. This is my fourth line of chemo ie. Third recurrence.While my CA125 didn't go down to normal level it was decreasing steadily until I got my results yesterday for the fifth round . It had risen to 257 from 189. I was really upset with this. I feel
Seedlings
in
My Ovacome
8 days ago
First BAT cycle results: what next?
I started my first BAT cycle on 3-12-24, originally designed to last for 32 days.
PSA was 0.5
and I injected 50 mg eod of T propionate and .625 mg of letrozole every 3rd day to inhibit conversion of T to E2. Here are my blood test results during the cycle followed by a couple of questions:
I started my first BAT cycle on 3-12-24, originally designed to last for 32 days.
PSA was 0.5
and I injected 50 mg eod of T propionate and .625 mg of letrozole every 3rd day to inhibit conversion of T to E2. Here are my blood test results during the cycle followed by a couple of questions:
Ichthus316
in
Fight Prostate Cancer
9 days ago
Treatment options
I am 47 years old diagnosed with PC last month with Gleason score 9(5,4) and was advised ADT treatment with Bicalutamide and followed by Lupron 30 mg after two weeks. PSA was 77 in Jan and dropped to 23 after starting ADT treatment and already feeling better with much less urinary symptoms. I was advised
I am 47 years old diagnosed with PC last month with Gleason score 9(5,4) and was advised ADT treatment with Bicalutamide and followed by Lupron 30 mg after two weeks. PSA was 77 in Jan and dropped to 23 after starting ADT treatment and already feeling better with much less urinary symptoms. I was advised
mtechguy
in
Advanced Prostate Cancer
9 days ago
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