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Is this a lupus rash
Hey everyone.I'll try and keep this short. Ive been diagnosed with fibromyalgia, pernicious anemia, lots of back disc issues, an exploratory lap for endometriosis which came back clear, my thyroid labs are poor but in range so not medicated but I am positive for tpa antibodies. I have had a positive
Hey everyone.I'll try and keep this short. Ive been diagnosed with fibromyalgia, pernicious anemia, lots of back disc issues, an exploratory lap for endometriosis which came back clear, my thyroid labs are poor but in range so not medicated but I am positive for tpa antibodies. I have had a positive
Peppermints
in
LUPUS UK
6 months ago
How long for ANA/ENA results?
I've had quite a few symptoms of what my GP suspects might be a CTD, spanning back about 10 years but lots more cropping up more recently. She's requested (I think) an ANA test and I understand from googling that if the ANA is positive it then gets sent for ENA testing as well? I'm not sure what the
I've had quite a few symptoms of what my GP suspects might be a CTD, spanning back about 10 years but lots more cropping up more recently. She's requested (I think) an ANA test and I understand from googling that if the ANA is positive it then gets sent for ENA testing as well? I'm not sure what the
Helzipop
in
LUPUS UK
6 months ago
Pentoxyfiline
hi I’ve been prescribed Trental 400 mg ( pentoxyfiline) for firearm pain and hand pain associated with Raynauds. The team who prescribed it have discharged me to local rheumatologist who doesn’t want to continue prescribing as it’s a black list drug. Since taking it I’ve only had 2 digital ulcers instead
hi I’ve been prescribed Trental 400 mg ( pentoxyfiline) for firearm pain and hand pain associated with Raynauds. The team who prescribed it have discharged me to local rheumatologist who doesn’t want to continue prescribing as it’s a black list drug. Since taking it I’ve only had 2 digital ulcers instead
Rubytunes
in
Scleroderma & Raynaud's UK (SRUK)
15 days ago
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Enzalutamide & 5-year survival in mHSPC.
More from ASCO 2023 [1] [2]. "Patients in the ENZAMET trial (n = 1125) were randomized 1:1 to arm A, the control arm consisting of TS plus a standard non-steroidal antiandrogen ([NSAA] bicalutamide, nilutamide, or flutamide), or enzalutamide at 160 mg per day plus TS in arm B. " "The 5-year OS rates
More from ASCO 2023 [1] [2]. "Patients in the ENZAMET trial (n = 1125) were randomized 1:1 to arm A, the control arm consisting of TS plus a standard non-steroidal antiandrogen ([NSAA] bicalutamide, nilutamide, or flutamide), or enzalutamide at 160 mg per day plus TS in arm B. " "The 5-year OS rates
pca2004
in
Fight Prostate Cancer
1 year ago
Darolutamide & time to treatment discontinuation in nmCRPC
Further to the recent Apalutamide thred, we now have [1]: "A real-world analysis of the androgen receptor inhibitors (ARIs) darolutamide (Nubeqa), enzalutamide (Xtandi), and apalutamide (Erleada) found that darolutamide had a longer time to treatment discontinuation and longer time to progression to
Further to the recent Apalutamide thred, we now have [1]: "A real-world analysis of the androgen receptor inhibitors (ARIs) darolutamide (Nubeqa), enzalutamide (Xtandi), and apalutamide (Erleada) found that darolutamide had a longer time to treatment discontinuation and longer time to progression to
pca2004
in
Fight Prostate Cancer
1 year ago
Lupus diagnosis yesterday
Hello everyone, been a tricky few months. You all know what it's like.just wanted to update and i feel a bit overwhelmed. In 2020 was diagnosed with UCTD. Positive ANA. Take hydroxychloquine. Last year ENT diagnosed sjogrens, it was an urgent 2 week referral as my throat had been sore for months
Hello everyone, been a tricky few months. You all know what it's like.just wanted to update and i feel a bit overwhelmed. In 2020 was diagnosed with UCTD. Positive ANA. Take hydroxychloquine. Last year ENT diagnosed sjogrens, it was an urgent 2 week referral as my throat had been sore for months
BonnyB
in
LUPUS UK
6 months ago
My Last (IFN) Dose, my Fateful Decision One Year Ago
This is a long and not cheerful post, I understand if you don’t wish to wade fully or at all thru it. Sections are marked for easy reference. The thoughts are my opinions only. -- I wrote a few months ago on my botched flu vax anniversary. Today is the one year mark for my Last Dose of Besremi
This is a long and not cheerful post, I understand if you don’t wish to wade fully or at all thru it. Sections are marked for easy reference. The thoughts are my opinions only. -- I wrote a few months ago on my botched flu vax anniversary. Today is the one year mark for my Last Dose of Besremi
EPguy
in
MPN Voice
6 months ago
Weak positive
Hi there I had a weak positive ANA it said speckled and 1.80 My dr has said no other action needed. Do I have the beginning of lupus. I already have type 1 diabetes, hashimoto and vitiligo. Thanks for any advice
Hi there I had a weak positive ANA it said speckled and 1.80 My dr has said no other action needed. Do I have the beginning of lupus. I already have type 1 diabetes, hashimoto and vitiligo. Thanks for any advice
Demilouise
in
LUPUS UK
6 months ago
Implications of positive if ‘weak ANA test’?
I have dry-eye confirmed by Moorfield’s. I also have dry mouth and my dentist said she suspected I had Sjorgren’s. When tested I proved to have a ‘weak positive ANA test’. What, if anything does that mean?
I have dry-eye confirmed by Moorfield’s. I also have dry mouth and my dentist said she suspected I had Sjorgren’s. When tested I proved to have a ‘weak positive ANA test’. What, if anything does that mean?
Morganalefaye
in
Scleroderma & Raynaud's UK (SRUK)
6 months ago
Lupus questions
Good afternoon, My doctor has been helping me with some ongoing symptoms, and following a positive ANA test has now referred me to a rheumatologist, theorising I may have Lupus. Anti-nuclear factor level POSITIVE - Titre > 1:640 ANA PATTERN SPECKLED My symptoms are: - mild arthritis in my neck, back
Good afternoon, My doctor has been helping me with some ongoing symptoms, and following a positive ANA test has now referred me to a rheumatologist, theorising I may have Lupus. Anti-nuclear factor level POSITIVE - Titre > 1:640 ANA PATTERN SPECKLED My symptoms are: - mild arthritis in my neck, back
EllsBells591
in
LUPUS UK
6 months ago
Piles
Last year I was diagnosed with a anal fissure and piles I was given suppositories and laxatives and it all cleared up.Had a issue a few months ago when I throught there was a small amount of blood went to the doctor who examined me and said everything was fine and not to worry and that it could have
Last year I was diagnosed with a anal fissure and piles I was given suppositories and laxatives and it all cleared up.Had a issue a few months ago when I throught there was a small amount of blood went to the doctor who examined me and said everything was fine and not to worry and that it could have
lut123
in
IBS Network
10 months ago
Aplautamide, enzalutamide: low dose opinions
Hi Officially mcrpc. Can't get darolutamide so faced with choice of zytiga, xtandi or aplautamide in the coming weeks. Faced with the first two I would have opted for xtandi and hopefully worked towards taking two tablets. Maybe one but have seen a few progress at one and wonder if two would be an
Hi Officially mcrpc. Can't get darolutamide so faced with choice of zytiga, xtandi or aplautamide in the coming weeks. Faced with the first two I would have opted for xtandi and hopefully worked towards taking two tablets. Maybe one but have seen a few progress at one and wonder if two would be an
Rickytarr
in
Fight Prostate Cancer
1 year ago
road to diagnosis
Hi everyone, I don’t know where to start… it’s been a bit of a rollercoaster so far. It all started when I started getting redness and discolouration in both feet. My GP did a blood test and referred me to my rheumatologist for further assessment. My rheumatologist felt that my feet getting red was
Hi everyone, I don’t know where to start… it’s been a bit of a rollercoaster so far. It all started when I started getting redness and discolouration in both feet. My GP did a blood test and referred me to my rheumatologist for further assessment. My rheumatologist felt that my feet getting red was
RA_123
in
LUPUS UK
7 months ago
Caffeic acid phenethyl ester [CAPE]
New study [1]. "
Caffeic acid phenethyl ester suppresses EGFR/FAK/Akt signaling, migration, and tumor growth of prostate cancer cells
" There have been 2 dozen CAPE papers these last 20 years. Ten of these specifically mention Akt inhibition. CAPE is found in propolis, which bees use to seal
New study [1]. "
Caffeic acid phenethyl ester suppresses EGFR/FAK/Akt signaling, migration, and tumor growth of prostate cancer cells
" There have been 2 dozen CAPE papers these last 20 years. Ten of these specifically mention Akt inhibition. CAPE is found in propolis, which bees use to seal
pca2004
in
Fight Prostate Cancer
1 year ago
Ivermectin on Pub Med
{From a related web site} In summary, our results indicate that ivermectin suppressed the AR and E2F signaling pathways and DNA damage repair capacity by targeting FOXA1 and Ku70/Ku80 to inhibit cell proliferation and promote cell apoptosis in prostate cancer. These findings provide insight into both
{From a related web site} In summary, our results indicate that ivermectin suppressed the AR and E2F signaling pathways and DNA damage repair capacity by targeting FOXA1 and Ku70/Ku80 to inhibit cell proliferation and promote cell apoptosis in prostate cancer. These findings provide insight into both
cigafred
in
Fight Prostate Cancer
1 year ago
Mouth ulcers
Hi everyone now on my fourth week of HU and another side effect.Any top tips for mouth ulcers would be appreciated.
Hi everyone now on my fourth week of HU and another side effect.Any top tips for mouth ulcers would be appreciated.
Spanelmad
in
MPN Voice
9 months ago
Strategies to Re-Sensitize Castration-Resistant Prostate Cancer to Antiandrogen Therapy
New paper from Spain [1]. "... we will review those strategies and drugs that are able to resensitize cancer cells to previously used treatments through the use of "hinge" treatments with the objective of obtaining an oncological benefit. "
Some examples are:
[i]
bipolar androgen therapy (
New paper from Spain [1]. "... we will review those strategies and drugs that are able to resensitize cancer cells to previously used treatments through the use of "hinge" treatments with the objective of obtaining an oncological benefit. "
Some examples are:
[i]
bipolar androgen therapy (
pca2004
in
Fight Prostate Cancer
1 year ago
Fistula + Stage 4 Endo
Hi, I have ended up in urgent care due to a lump that keeps bleeding in my belly button. I had surgery in 2020 to help remove some of the endometriosis however since then I have always had a slight lump. I thought it was just healing however last couple of months its got bigger, darker and more painful
Hi, I have ended up in urgent care due to a lump that keeps bleeding in my belly button. I had surgery in 2020 to help remove some of the endometriosis however since then I have always had a slight lump. I thought it was just healing however last couple of months its got bigger, darker and more painful
MsTMP
in
Endometriosis UK
1 year ago
bowel endo issues
Hi all, I have deep infiltrated endo on my bowel (diagnosed via scan and mri 3 years ago) and superficial on my uterus but my bowel issues have been getting worse lately probably after all the pain medications and hormone treatment i’ve been trialling to avoid surgery! It’s to the point now I can
Hi all, I have deep infiltrated endo on my bowel (diagnosed via scan and mri 3 years ago) and superficial on my uterus but my bowel issues have been getting worse lately probably after all the pain medications and hormone treatment i’ve been trialling to avoid surgery! It’s to the point now I can
Karen_92
in
Endometriosis UK
11 months ago
Thoughts and Help
Hello all! I am new here. I know this is a lupus / autoimmune group, but before joining I noticed some helpful posts for other conditions, so I am hoping I can find some advice here. I have been dealing with declining health for a few years now, but have not received any diagnoses. I do have a positive
Hello all! I am new here. I know this is a lupus / autoimmune group, but before joining I noticed some helpful posts for other conditions, so I am hoping I can find some advice here. I have been dealing with declining health for a few years now, but have not received any diagnoses. I do have a positive
Hidden
in
LUPUS UK
8 months ago
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