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FDA Grants Priority Review to Olaparib for HRR-Mutant mCRPC - Targeted Oncology - January 20, 2020
The PROfound study showed that olaparib reduced the risk of disease progression or death by 66% compared with pcNHA (HR, 0.34; P <.0001) versus
abiraterone
or enzalutamide.
The PROfound study showed that olaparib reduced the risk of disease progression or death by 66% compared with pcNHA (HR, 0.34; P <.0001) versus
abiraterone
or enzalutamide.
cujoe
in
Fight Prostate Cancer
4 years ago
Abiraterone Acetate 250mg Tablets
I have 107 unused tablets, I will send to USA address Expiration date Oct 2020
I have 107 unused tablets, I will send to USA address Expiration date Oct 2020
Hidden
in
Advanced Prostate Cancer
4 years ago
When should the next set of scans be?
Then started
Abiraterone
(zytiga) on 11/1/19. PSA is currently 11 as of 12/24/19 My question is: when should his next scans be and WHAT should they be? (Bone scan? Another PET?) Really appreciate any opinions. Thank you!
Then started
Abiraterone
(zytiga) on 11/1/19. PSA is currently 11 as of 12/24/19 My question is: when should his next scans be and WHAT should they be? (Bone scan? Another PET?) Really appreciate any opinions. Thank you!
j5000
in
Advanced Prostate Cancer
4 years ago
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niclosamide - UC Davis Clinical Trial......in edit, what about artemisinin, which works for dogs with bone cancer?
Besides the anti cancer mechanisms you outlined, PDMX1001/niclosamide can resensitize the cancer to
abiraterone
and enzalutamide They have shown in vitro that niclosamide can revert mechanisms in the cancer cells which make the cancer resistant to abi or enza.
Besides the anti cancer mechanisms you outlined, PDMX1001/niclosamide can resensitize the cancer to
abiraterone
and enzalutamide They have shown in vitro that niclosamide can revert mechanisms in the cancer cells which make the cancer resistant to abi or enza.
JLS1
in
Advanced Prostate Cancer
4 years ago
Bio-Chemical Relapse that's me 3rd recurrence. But Clinical Relapse? Help me understand.
I could or should do some research myself but my mind is in on overload with
Abiraterone
and Prednisone 18 days in and still forcing me to exercise 2X daily. Any places I could look for mind overload EEC Doug?
I could or should do some research myself but my mind is in on overload with
Abiraterone
and Prednisone 18 days in and still forcing me to exercise 2X daily. Any places I could look for mind overload EEC Doug?
depotdoug
in
Advanced Prostate Cancer
4 years ago
Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer
agent (
abiraterone
or enzalutamide).
agent (
abiraterone
or enzalutamide).
MateoBeach
in
Advanced Prostate Cancer
5 years ago
Dr says Enzalutimide... what about Cabazitaxel?
prostate cancer who had been previously treated with docetaxel and the alternative androgen-signaling-targeted agent (
abiraterone
or enzalutamide)."
prostate cancer who had been previously treated with docetaxel and the alternative androgen-signaling-targeted agent (
abiraterone
or enzalutamide)."
Tak-Druk
in
Advanced Prostate Cancer
4 years ago
Rising creatinine with zoledronic acid infusions...
(on
abiraterone
for past 1 year and psa started rising this june.doc has advised to continue taking
abiraterone
and has prescribed zoledronic infusions).
(on
abiraterone
for past 1 year and psa started rising this june.doc has advised to continue taking
abiraterone
and has prescribed zoledronic infusions).
Vsahay
in
Advanced Prostate Cancer
5 years ago
PCa advice
I have heard other members start off with HT and
Abiraterone
or something similar and wondered why you would pick one over the other. 2) oligometatasis talks about 5 hot spots or less. Is there any clarification on the size of these spots?
I have heard other members start off with HT and
Abiraterone
or something similar and wondered why you would pick one over the other. 2) oligometatasis talks about 5 hot spots or less. Is there any clarification on the size of these spots?
SC19
in
Advanced Prostate Cancer
5 years ago
What should I do? Or do what my MO's decision path is for me!
Is 4 - 250mg
Abiraterone
tabs daily an avalanche ready to fall? 2] My cost for 120 tabs monthly of 250mg
Abiraterone
is $990.00 my cost. Insurance pays a whopping $2,100 of $3,300 monthly.
Is 4 - 250mg
Abiraterone
tabs daily an avalanche ready to fall? 2] My cost for 120 tabs monthly of 250mg
Abiraterone
is $990.00 my cost. Insurance pays a whopping $2,100 of $3,300 monthly.
depotdoug
in
Advanced Prostate Cancer
5 years ago
Abiraterone aka Zytiga. Loading effect time
Well day 3 of minimally ingested 250mg tab. My newest, I said newest Chemo-cancer pharmacist just told me. 1. 2 hours absorption into my body ? 2. ~~ 1 week till total loading effect. ? I have not re-read my Pharmacological data pack yet. Those are my ? marks on the two points. Anybody can shed light
Well day 3 of minimally ingested 250mg tab. My newest, I said newest Chemo-cancer pharmacist just told me. 1. 2 hours absorption into my body ? 2. ~~ 1 week till total loading effect. ? I have not re-read my Pharmacological data pack yet. Those are my ? marks on the two points. Anybody can shed light
depotdoug
in
Advanced Prostate Cancer
5 years ago
Abiraterone acetate (1) 250mg tab with food same as 4 without food?
Today late breaking news::::::: My ONC pharmacies pharmacist told me (1) 250mg
ABIRATERONE
Acetate tab with food(meal) is as effective as (4) 250mg ingested on empty stomach. Where is this Clinical Study found.?? Help me fellow pharmacology experts.
Today late breaking news::::::: My ONC pharmacies pharmacist told me (1) 250mg
ABIRATERONE
Acetate tab with food(meal) is as effective as (4) 250mg ingested on empty stomach. Where is this Clinical Study found.?? Help me fellow pharmacology experts.
depotdoug
in
Advanced Prostate Cancer
5 years ago
What are your thoughts about adaptive therapy for Prostate Cancer?
The patients were put on the drug
abiraterone
, or Zytiga, and researchers tracked the tumors by monitoring a protein called PSA in their blood, as unusually high levels of the protein are linked to prostate cancer.
The patients were put on the drug
abiraterone
, or Zytiga, and researchers tracked the tumors by monitoring a protein called PSA in their blood, as unusually high levels of the protein are linked to prostate cancer.
jronne
in
Advanced Prostate Cancer
4 years ago
More data from the LATITUDE study.
KEYWORDS:
Abiraterone
; Metastatic castration-sensitive prostate cancer; Overall survival; Prostate-specific antigen kinetics; Radiological progression-free survival PMID: 31843335 DOI: 10.1016/j.eururo.2019.11.021
KEYWORDS:
Abiraterone
; Metastatic castration-sensitive prostate cancer; Overall survival; Prostate-specific antigen kinetics; Radiological progression-free survival PMID: 31843335 DOI: 10.1016/j.eururo.2019.11.021
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Hazardous Drug bag arrived Day#1 Abiraterone 250mg prednisone
Should I expect unusual things to happen?? Like when I start exercising @08:30 - 10:00? Like feeling different? Like worrying about SE’s. Like just seeing my Hazardous Drug bag? On counter? Like loss of energy? Depotdoug
Should I expect unusual things to happen?? Like when I start exercising @08:30 - 10:00? Like feeling different? Like worrying about SE’s. Like just seeing my Hazardous Drug bag? On counter? Like loss of energy? Depotdoug
depotdoug
in
Advanced Prostate Cancer
5 years ago
10mg Prednisone daily Energy Rampant- not Sleeping much
26 days on 1st experience w/ Prednisone 5mg 2X/ day. 1st 1 AM w/
Abiraterone
250mg. Excessive Exercising Energy explodes. That’s Ok. 2nd Prednisone 5mg 4-5PM. Excessive Energy increases till bedtime.
26 days on 1st experience w/ Prednisone 5mg 2X/ day. 1st 1 AM w/
Abiraterone
250mg. Excessive Exercising Energy explodes. That’s Ok. 2nd Prednisone 5mg 4-5PM. Excessive Energy increases till bedtime.
depotdoug
in
Advanced Prostate Cancer
4 years ago
Lupron--every three months? or every six months?
Mets to pelvis (fracture of the pelvis), spine and ribs. 10 rounds of external beam radiation on pelvis and base of spine 10/4/2019: received Firmagon and Xgeva Shot (monthly) 11/1/2019: started on
Abiraterone
.
Mets to pelvis (fracture of the pelvis), spine and ribs. 10 rounds of external beam radiation on pelvis and base of spine 10/4/2019: received Firmagon and Xgeva Shot (monthly) 11/1/2019: started on
Abiraterone
.
j5000
in
Advanced Prostate Cancer
5 years ago
2019 Top Stories in Advanced Prostate Cancer: Cabazitaxel vs Abiraterone or Enzalutamide in Metastatic Prostate Cancer
or enzalutamide) in men who had previously been treated with docetaxel or the other androgen signaling–targeted inhibitor (ie,
abiraterone
or enzalutamide).
or enzalutamide) in men who had previously been treated with docetaxel or the other androgen signaling–targeted inhibitor (ie,
abiraterone
or enzalutamide).
Balsam01
in
Advanced Prostate Cancer
5 years ago
A brief story of using Trintellix (Brintellix) antidepressant
So, if you plan to take an SSRI antidepressant together with
Abiraterone
, be aware of the potential interaction between the drugs. Peace
So, if you plan to take an SSRI antidepressant together with
Abiraterone
, be aware of the potential interaction between the drugs. Peace
dorke
in
Advanced Prostate Cancer
5 years ago
Therapies Targeted to Androgen Receptor SignalingAxis in Prostate Cancer: Progress, Challenges,and Hope - published December 2019
T878A or L702H mutations were found in the plasma of 13% of CRPC patients with
abiraterone
resistance [23]. These muta-tions can be detected in plasma DNA and may help physicians in choosing the appropriate drugs for CRPC patients [24].
T878A or L702H mutations were found in the plasma of 13% of CRPC patients with
abiraterone
resistance [23]. These muta-tions can be detected in plasma DNA and may help physicians in choosing the appropriate drugs for CRPC patients [24].
JLS1
in
Advanced Prostate Cancer
5 years ago
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