Abiraterone aka Zytiga. Loading effect time

[depotdoug]

Well day 3 of minimally ingested 250mg tab.

My newest, I said newest Chemo-cancer pharmacist just told me.

1. 2 hours absorption into my body ?

2. ~~ 1 week till total loading effect. ?

I have not re-read my Pharmacological data pack yet. Those are my ? marks on the two points.

Anybody can shed light?

[Tall_Allen]

1. abiraterone is slowly absorbed through the gut. More quickly with fat.

2. it slowly builds up in your bloodstream. He is saying that it takes a week of daily intake until it reaches its maximum concentration. After that, the daily amount absorbed=the daily amount excreted. This is called the "steady-state concentration."

[FenBenGolf]

I have been taking 1000mg of abiraterone daily for 6 weeks. PSA down to <0.3. Originally in the hundreds. Lupron brought it down to around 0.7 for a couple of years. It then started to rise and after it got to 1.3 or so Dr said this was next step. Should work for a year or so. Still doing Lupron shots quarterly. Hip and sacrum pain has gone away.

[Cisco99 in reply to FenBenGolf]

This was my experience exactly.

[depotdoug in reply to FenBenGolf]

No SE’s from 1,000mg Abiraterone?