This is the name of an article that explains why and how too much dopamine CAN cause all kinds of problems. livestrong.com/article/3815... Someone had mentioned that because dopamine is made naturally by our bodies, we cannot gte too much. NOT true at all. Dopamine toxicity is very serious. But read the article and see for yourself. I read several before I posted this one to be sure. Dopamine can raise your blood pressure, because it pushes the blood thru the veins faster, hence why RLS could forseeably be connected with high bloood pressure because of the meds some of us take. If our dopamine levels are "normal" and we are still getting RLS, then dopamine may not be your problem at all. That is why the Parkinson's meds like Mirapexin and Ropinerole, plus the Neupro patch do not work for all of us, or the side effects `are too severe to be taking it. That is why I go a little nuts when I see how high the doses of some of the dopamine meds on this site and others. Too much dopamine is as dangerous as too much iron, or iron overload. And, dopamine "conducts" the iron through our veins. It is all mixed up together, so may explain why iron helps SOME people, dopamine meds help SOME, and others of us have to look farther than that to get any relief.