Hi, I found out I probably had PBC about 6 months ago and after plenty of blood tests, Fibroscan & Biopsy it was officially confirmed to me last week. I have absolutely no symptoms and only found this out due to a random blood test taken while I was pregnant which did not go to term. I have just been prescribed 250mg per day of Urso to see how it goes. The pharmacist said the Urso will probably cause me diarrhoea for the first week and then possibly the itching a lot of people speak about. Does the Urso cause the itching or does the disease cause the itching? I'm dreading going from no symptoms to having this itch that so many people suffer from.