Hello. I have recently been diagnosed with PBC; a disease I'd never heard of until now. I'm thankfully in stage 1 with just inflammation and a little fibrosis of the small ducts and hope to maintain that level for the duration. I do seem to be rather old (nearly 60) for an initial diagnosis and wonder if others have been diagnosed past 50 and what your experience has been? I just started Urso and it is definitely NOT agreeing with me as my symptoms seem worse. I'm wondering if the Urso has helped alleviate your symptoms? I have been experiencing increasing fatigue,no stamina, night-time itching, elevated LFTs and soaring levels of cholesterol. Is it your experience that the Urso helps with the LFTs and limits progression of the disease, but doesn't really give much symptomatic relief? Again, it's such a wonderful thing to find a community of people sharing their knowledge and experience with this disease and treatments. My thanks in advance for any assistance with my questions. Best to all!