Hi, I'm new here. I was diagnosed with PBC a couple of months ago and have been on urso since, it does seem to be helping with the fatigue so far. After seeing a consultant he said I should have a biopsy which I have now had and am awaiting the results. I asked him why I needed a biopsy and he said he suspects AIH as well. I am confused as to why he would think this when my ANA result was negative. Does anyone know what else might indicate AIH? This site has been a great comfort in these early days, thanks to all.