I have been on URSO since jan 2014 following positive AMA and raised ALP of 135. ALT has been around 60 for a year and after 6 weeks on URSO came down to 40. My ALP came down to 99. 6 weeks further on ALT is now up to 50. My specialist had said in March that he was happy that the ALT was coming down but if it stayed over 40 or was going up he would consider a liver biopsy to check for AIH/PBC overlap and also to stage my PBC. I am currently asymptomatic. Does anyone have experience of being investigated for AIH overlap or for liver biopsy? One minute I'm fine the next I'm freaking out thinking I might be a few years away from needing a new liver I'm only 33! Thanks in advance
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