Anemia Real concern need some advice

[Dedikodu]

Anemia Real concern need some advice

I am breathless and fatigued and diagnosed with Anemia, but Iron/b12 levels are normal/high not lifestyle or food-related.

I also had a stiff neck and all-over pain on rising in the morning so they first thought it was Polmalgia and put me on steroids but it didn't get the reaction expected from Polymalgia so was tapered off steroids

I had been having blood tests and when one came back showing my Serum Immunoglobulin M rate was 3... I was told they were putting me on the 2-week urgent Cancer haematologist appointment .... but it didn't reach that far, and I was put on triage and got a phone call to say on looking at past blood tests no trace of cancer phew....

So back to square one and the breathlessness and fatigue is a little worse from the initial stage from someone who could easily do 10,000 steps I am now down to less than 4000 steps and need to rest after ...

I am concerned as this Anemia is untreated with no suggestions of medication or treatment for more than 4 months. And know word from the Dr if further investigation ..which worries me and never had an actual face-to-face meeting but done by phone mainly on my instigation ... I also think there may be some personality cognitive change but that could be down to anxiety and lack of sleep with worry ...

any help or advice is gratefully received thank you

My last blood tests showed .. this below but have been worse ...but these are out of range ...

Haematocrit 0.335

Haemoglobin 106

Neutrophils 8.29

Platelet Count 498

RDW 15.3

White Cell Count 10*9/L

Serum Alanine transaminase 9

[FlipperTD]

Scientist, not medic.

Sorry to be a nuisance, but the rest of the FBC data would be helpful, including ranges given. If you have earlier results that would help too.

[Dedikodu in reply to FlipperTD]

Kappa/Lambda ratio

N/A

The results will be available on 03 April 2025 at 01:00

Serum free Kappa

N/A mg/L

Serum Immunoglobulin 1.62 g/L in range

Serum Immunoglobulin G

Not assayed, see paraprotein level.

Serum Immunoglobulin M 3 g/L out of range

Serum Paraprotein level

N/A g/L

The results will be available on 27 March 2025 at 00:00

Serum Protein Electrophoresis N/A

The results will be available on 27 March 2025 at 00:00

Basophils 0.06 10*9/L no change in range

Eosinophils 0.09 10*9/L 0. 02 decrease in range

Haematocrit 0.335 +0.005 increase out of range

Haemoglobin 106 g/L +4 increase out of range

Lymphocytes 2.73 10*9/L -0.32 decrease in range

MCH 27.2 pg +0.9 increase in range

Mean Cell Volume 86.1 fl +1 increase in range

Monocytes 0.78 0*9/L -0.06 decrease in range

Neutrophils 8.29 10*9/+1.09 increase out of range

Nucleated RBC 0 10*9/L no change in range

Platelet Coun 498 10*9/L -3 decrease out of range

RDW 15.3% -0.1 decrease out of range

Red Cell Count 3.89 10*12/L +0.01 increase in range

Serum Albumin 40 g/L -2 decrease in range

Serum Total Protein 76 g/L +5 increase in range

White Cell Count 11.95 10*9/L +0.69 increase out of range

Urine Creatinine 4955 umol/L

Urine Electrophoresis

Urine Total Protein 0.05 g/L

HbA1c (IFCC Standardised) 47 mmol/mol +9 increase out of range

Adjusted Calcium 2.59 mmol/L in range

Calculated Non-HDL Cholesterol

3.3 mmol/L -0.5 decrease out of range

eGFR (CKD-EPI)

90 mL/min/1.73m2 +3 increase

ESR 120 mm/h +7 increase out of range

LDL Cholesterol (Sampson Eqn) 2.8 mmol/L -0.4 decrease in range

Serum 25-OH Vitamin D (D2 +D3)

153 nmol/L

Serum Alanine transaminase

9 U/L -1 decrease out of range

Serum Alkaline Phosphatase

64 U/L -3 decrease in range

Serum Calcium

2.51 mmol/L

Serum Cholesterol

4.7 mmol/L -0.5 decrease in range

Serum Cholesterol/ HDL ratio

3.4 -0.3 decrease

Serum Creatinine

51 umol/L -1 decrease in range

Serum CRP

51 mg/L +13 increase out of range

Serum ferritin

441 -28 decrease out of range

Serum folate

2.6 ug/L -1.1 decrease in range

Serum HDL Cholesterol

1.4 mmol/L no change in range

Serum Inorganic Phosphate

1.16 mmol/L in range

Serum Potassium

4.9mmol/L no change in range

Serum Sodium

138 mmol/L no change in range

Serum Total Bilirubin

3 umol/L no change

Serum Triglyceride

1.3 mmol/L -0.1 decrease in range

Serum TSH

1.35 mIU/L -0.59 decrease in range

Serum vitamin

B12 838 ng/L -178 decrease out of range

Faecal Test for Haemoglobin

<2 ug/g ug/g

eGFR (CKD-EPI)

90

Serum Total Creatine Kinase

130U/L -29 decrease in range

Serum Urea 7.2

[Mrl1234]

Have you had B12, homocysteine, urine MMA testing done? If not, I'd start there. But PA doesn't always show up in blood work. (Not medical advice) but you could always try a b vitamin complex or just b 12 to see how you feel on it. But I'd wait to supplement until testing bc supplementation can throw false negatives. Try to get blood labs asap so you can see if b vitamins help you. I was so bad I could barely walk around the block and had to sit to shower. Now I do an oral b 12 (for now, until injections) and I was able to get back to work.

[Dedikodu in reply to Mrl1234]

I have taken B12 for years unfortunately its not helping this. Dr wants to find the cause of the anemia before treating it we are now going down the RA route and will be having an MRI scan .

[Mrl1234 in reply to Dedikodu]

Are you taking b12 orally or injecting? Sometimes the stomach doesn't have the right things to be able to digest the b12 and convert into a useful source (methylation).