Wwwdot wrote something to the effect that the process of self treating is counter intuitive and someone else wrote that they needed higher amounts than thought to be need to heal. Reading this led me to pondering.
If you had told me 4 years ago that I would have to design a way to self-treat that goes against what the medical field was confident was unnecessary I would have questioned your mental balance.
It is not unlike when as a consultant I would be on a site and the person would say I designed it myself and I would think I knew some idiot did when drove in the driveway. This once was a licencee architect. We ended up doing a lot of work together once he understood he did not know how to design a lot. I do not know how to design buildings.
It is counter intuitive for me to administer supplements in amounts much greater than advised. including by the cut and paste non-experts with no experience of severe B12D that very frequently cut and paste advice and instruction.
B12, Methyl Folate, P-5-P, Vitiman D3, K2, Betaine, Magnesium are supplements that my body needs to heal in amounts greater than what is thought to be true. That took years to establish by trials.
It came to me that I did trials of Methyl Folate, D3, K2 and Betaine and the trials indicated they had no effect. The reason was that I administered the recommended amount.
I have an advantage as a scientist as I know in my field of environmental science we use science and then use applied science that is constantly being improved. I was able to review the justification for the recommended amounts and see the flaws and why they existed. Much of about feeling safe with better/mediocre results and not having the courage to excel.
I do not think I would have dared to self treat this way without those that shared there success with doses higher than recommended. It did take me a while to understand some on this forum who instruct and advise do so from the perspective of what might be seen as B12D Lite or are following the recommendations and may not be healing at a level that is possible by not following. That is their choice and I only object to the advice and instruction as it is wrong other than for B12D Lite.
I do not see forcing GP's to follow the guidelines as a solution only a less mediocre method. It would be nice if they would at least do what they are getting paid to do. We have the same issue in my field.
If you had told me 4 years ago that I would be able to self treat with a level of success not even known to the late great Dr. Chandy I would have thought you a fool. His work was ground breaking 30+ years ago.
When I improve my supplementation I need a lot of rest and sleep. Sometimes 14 hours + (this is hard as I need to set an alarm to wake up an supplement. That only lasts a few days now with improved self-treatment.)
The needing more sleep and rest is not counter intuitive. It is hard to go through as it is disruptive. I have to have food ready to eat before I start a new trial. It is very hard for me as feeling worse hoping that I will feel better is hard. There is the aspect than I fear causing fatigue. That is less of a fear with my success. I also do not wake up fatigued now rather just tired from healing. I did not and could not understand the difference between fatigue and being tired until the fatigue was mitigated to a large degree.
I do not hold the false belief that I know what you experienced or what you will experience with any amount or type of supplementation. I do know that those that claimed to know how I should self treat were WRONG.
Note: We all decide what we mean by 'works'.
Brain damage caused by b12 deficiency
GP refusing treatment - what to do next?
Self treatment for PA symptoms, is it possible?
Neurological symptoms: self injecting how long to see some improvement. 
