Latest 14 day trial.

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Not a trial of volume rather a trial of constant frequency. A trial to explore a hypothesis. Not seeing if I can stumble on something ‘that works’.

I consider injecting the same amount less frequently as under supplementation.

Note: frequently is not meaningful unless there is a number. Twice a month is frequently compared to once a month.

I had just finished a 14 day trial of 1 mg of methylcobalamin and 1 mg of adenosylcobalamin every 4 hours and am guessing the results were positive. The results were not definitive. I 4 months ago started injecting every 4 hours which was definitely more effective and therefore effective. The three years prior were floundering.

Based on my current understanding of B12 I chose to do a trial of every 5 hours including setting my alarm to inject to meet this schedule.

As expected there was an immediate blip of improvement. I have found this to be true whenever I try a new trial other than reduction. I enjoy it for what it is and expect a downturn as my body adjusts to improved self treatment.

The first 7 days were hard as there were changes and changes are hard. I had to stay with my intellectual understanding as emotionally I wanted to slow down the healing/change.

Somewhere along the way it came to me that what I was experiencing was very similar to what I experienced at times my whole life and before I knew anything about B12 deficiency.

I see this as reversing out. I see my experience of the symptoms becoming more acute and debilitating as the results of under supplementing 1 mg of B12 per day.

The next 6 days were disconcerting because there was such a dramatic change. Although I made errors I would not normally make, having made those errors was a much more pleasant experience. I went to pick someone up at the airport 14 hours early. I got out of my car and it was out of gear and it rolled away. I did catch it. I accepted that healing my neurological system was not likely to be smooth sailing. These were not distressing experiences as they would have been when under supplimeting.

I know when my white blood cell count is low. I have had it tested and been prescribed antibiotics so many times I can tell. My white blood cell count is now within range. I do wonder if my body is now not attacking me and that is the result of the normal white blood cell count. That I am not in pain because my white blood cell count is in range is also a possibility.

I once had a physical and a physician prescribed antibiotics. I told the physician I would call him when it was back in range. That is what happened.

I did experience some sleep disturbance. Not clinical but not the sleep I have come to enjoy as I improve my self treatment.

On the 14th day I had a wonderful day and the 15th morning was also wonderful. Then I was spent and needed to eat and sleep. The rest of the day was hard but not on the level of needing to recover as when I was under supplementing. I do not miss that experience at all.

Whenever I improve my self treatment I find I need more sleep and rest. Worrying about is it fatigue again is part of the challenge of healing.

I did have acid reflux for a day and I thought, wonderful I have achieved acid reflux. I then remembered that I had that once before in my life when I was 10 and healing from the most severe B12 deficiency of my life prior to November 20 2020. When I was 10 the symptoms were more acute other than the fatigue. I had seizures at that time.

There was a lot of unlearning to be done that is not the same as the unlearning of what is thought to be true about B12. I had to unlearn again that I was not going to out of breath in the same way. I would stumble a bit and had to unlearn that is normal and it was in part as I was getting used to not having balance issues and risking stumbling more. I no longer need to prepare to go into a store as I no longer have the same physical reaction. I get tired at the end of the day rather than fade from under supplementation.

Twice I forgot to inject for 9 hours as I forgot I was suffering from the effects of being B12 deficient. That did not seem to have an adverse effect.

Note: I came to understand that I was incorrect and there was an adverse effect of not injecting for 9 hours. I worked on that and came to understand that I am now experiencing what is most accurately defined as subclinical symptoms. I am experiencing symptoms of having been B12 deficient and by my under self treatment for three years. I checked a list of symptoms associated with B12 deficiency and at this time do not by symptom meet the requirements for a B12 deficiency diagnosis.

This is a helpful distinction. It is not as remarkable as one might think as that has been the case since I started injecting every four hours 4 months ago. It is an achievement caused by my understanding of how B12 works.

I am thinking I am not suffering the physical manifestations of B12 deficiency and not in physical distress. I am experiencing neurological distress from having been B12 deficient and the 3 years of under supplementing while I studied so I could create my hypothesis(s).

Pretty much being subclinical for me is the minimum requirement for stating what works. That does not work well enough for me personally.

Someday I may write a top ten list of what I enjoy about not under supplementing.

I am staying away from any new hypothesis about my understanding of B12 as that may lead to another trial. I do not want to deal with the emotional decision of do I want to try a new trial in the hopes the new hypothesis leads to improvement which makes a winter crash less likely or the failure or strain of the new trial may increase the chances of a winter crash. The answer is not knowable so it is a matter of which way of failing would I be more OK with if I crashed.

Part of the emotional issue is I have been more successful with my last three hypotheses and the weather has been favorable for healing. It does not follow the weather will continue to be favorable. Nor does it follow that because the last three hypothesis panned out the next will. Having an understanding of probabilities and fallacious arguments is helpful.

I am working hard in hopes that supplementation is just something I do and can spend more energy on life. I have accomplished that my focus does not need to be on symptom reduction or elimination.

And there is the reality that two weeks is simply an indication. I will not need years to conclude it is probable I was correct. The results of my self treatment since injecting every four hours are measured in days with definitive improvement weekly. My current trial results in improvement better than weekly.

Injecting every 5 hours is not fun. The setting the alarm and injecting is no more not fun than the other injections for me. One time when I did not inject for 9 hours my body woke me up to inject prior to the alarm.

It is still a struggle just not in pain when trying to figure things out. A step in my process.