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Help B12 levels after loading dose and follow up treatment

GJOW profile image
GJOW
7 Replies

In Nov 18 I presented to my GP, anxiety, extreme tiredness, pins and needles in hands, extremely cold, ibs, headaches, brain fog. My blood tests revealed

B12 levels were 149 ng/l

Folate 2.7 ug/l

Vitamin D 43

My GP eventually agreed to a booster course of injections(5) the last one being on the 10th December and I was prescribed with 5mg folic daily til Jan. I have previously been tested for coeliac diseases but tested negative. I mentioned the instrinic factor test and was sent for this after the loading doses. This proved negative.

I have continuing symptoms and had a recent blood test on 23rd Jan 19 (some 6 weeks after the last loading dose) see above photo for results.

B12 levels were 511ng/l increased from previous test

Folate 6.6 ug/l increased from previous test

Vitamin D 39 Decreased from previous test

I have been prescribed Vitamin D tablets.

In relation to the B12 I have been told that as they cannot say whether it is a malabsorption (because of the neg result from instrinic factor) or diet related problem they will not continue with follow up injections and suggested I take a supermarket value range vitamin.

When I look at my B12 although it is now in range I would have expected it to be much higher as I had the loading doses. Do I need to pursue this further or do I assume I no longer have a B12 problem.

Looking for advice

Many thanks

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GJOW
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7 Replies
GJOW profile image
GJOW

Thank you I am hoping this is the information you were referring to

B12 Normal range 172-910 ng/l

Folate Normal RNge>5.40 ug/l

Vitamin D Normal Range 75-150 nmo/l

I complete understand my GP does not seem interested and even said when my B12 was 144 ng/l it was not really that low.

linkerror profile image
linkerror

What symptoms of IBS do you have and for how long? Celiac is known to cause B12D.

GJOW profile image
GJOW in reply tolinkerror

Hi I ve had IBS symptoms for many years but have been more since intense since approx Aug 17. I suffer from pain and cramping, diarrhea rather than constipation.

GastritisB12 profile image
GastritisB12

When was your last B12 injection? I am new here too, I have been reading up like mad.

This research shows that its possible to dip below 1000ug/L 2 months after loading injections. Who knows maybe even sooner?

Much more knowledgeable posters have posted that you may need to be over 1000 to fix neurological damage.

bloodjournal.org/content/bl...

GJOW profile image
GJOW in reply toGastritisB12

Hi thank you so much I will have a read. Yes there is much to read like you I want to understand it more and than this will also help me to be more educated and forewarned before I return to see the GP. The last injection of the loading doses I had was on the 10th Dec so within 6 weeks it was 511 ng/l. I notice my blood test refers to ng/l not ug/l.

GastritisB12 profile image
GastritisB12

Sorry you are right, my B12 test was in ng/l too. I think its a 1:1 between ng/l and the values in that study. Not 100% sure.

I hope you manage to get more injections and you get better.

GJOW profile image
GJOW in reply toGastritisB12

Aw thank you a steep learning curve for me. You take care too.

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