Help with B12 and folate levels

[Auntbessy]

I have a history of anaemia, low vit D and low B12 (i take igennus super B complex). I went down the route of exploring whether I had pernicious anaemia because I have a high MCH and b12 levels at the lower end. Ive been on high strength B12 supplements since April 2020. Now, what is weird is that my folate has gone up since xmas 19 but my b12 has actually gone down since taking these supplements.

e.g

previous folate and b12 levels:

folate 12.14 ug/l (range 3.9-19.45)

active b12 94.9 pmo/l (range 37.5-187.5)

current folate and b12 levels:

folate 19.8 ug/l (range 3.9-19.45)

active b12 87 pmo/l (range 37.5-187.5)

Is my current b12 level OK now?

I should also add that I have several PA symptoms.

[Nackapan]

Well you dont need to take a very high maintenance folic acid .!! Your b12 looks well in range

Were the levels alof lower before taking supplements ?

Have you been tested goes other things.

Thyroid ect ad symptoms do overlap.

Yoh say you got tested for PA?

Only picks uk 50% of those that have of

[Auntbessy in reply to Nackapan]

Good so you think my B12 is OK : ) previously my b12 was higher despite not taking supplements. Im on the thyroid forum as I have Hashimotos Thyroiditis. Yes, I do think and know symptoms overlap. The doc did an intrinsic factor test after seeing my high MCH (came back negative). I think at that point my B12 was just within range (bottom end). The administrators on there say that B12 has to be above 300 pg/ml to be well and symptom free. I have read that 500 pg/ml or over is best. I multiplied mine by 2.5 to convert it from nml/l to pg/ml which is 217.5. I appreciate I may sound like a total fusspot and I know some people here are contending with far worse B12 levels : (

[Nackapan in reply to Auntbessy]

Its just well in range .O think as feeling ill we strive to just do the best we can.

Over never studied blood forms as much.i bet if I felt well I woukdnd bother so much.

I used to have one yearly.

Puth it never had b12 on it!!

Others may co e along and say differently.

I know we all function at different levels .

I only took 400mcg folic acid and it took me over range.

Before b12 deficiency and illness

I took vitamin D and vitamin c

Assuming wrongly I was getting the nutrients from my very mixed diet

I hope you sed improvements soon.

I'm tempted to have a full nutritional screen once able. Just to add what I can or cannot absorb.

Very difficult once out of kilter to get if back.

[fbirder]

Yes, your Active B12 is high, which is good.

The test, while more accurate than the serum B12 test, still isn't accurate enough to be able to say that going from 94.9 to 87 is a real drop.

[FlipperTD]

Scientist, not medic, but...

It looks like your B12 is OK. [Active' is a better test in some ways but not that much better that I'd pay extra for it. Serum B12 would tell you the same with a different range.] If you're absorbing B12 from supplements without injecting then it's unlikely to be PA. [Let's not get into the arguments, as some folks with PA can, but it requires a lot of B12 and it's unclear how that works!]

Good luck.