Advice Please: Hi I was diagnosed with... - Pernicious Anaemi...

Pernicious Anaemia Society

32,623 members23,985 posts

Advice Please

UnitNitrogen73 profile image
7 Replies

Hi

I was diagnosed with B12 deficiency and Vit D deficiency in 2013. Once on 8 weekly injections and 2500 is of vitD3 I felt so much better. However, in 2016 I felt myself going down hill rapidly. My doctor feels it’s not the B12 deficiency causing my symptoms...I.e fatigue, tinnitus, pins and needles, light sensitivity etc. I had some blood tests done ( only a few days after my b12 injection ) and I am baffled by the results.

My homocysteine level was 9.9,

My MCH 32, MCV 95.5 MCHC 345 My potassium was 5.1 Creatinine 80umol/L

Zinc 13 (borderline )

My understanding is that B12 should reduce levels of Homocysteine, MCH and potassium ( which I understand can be depleted quite significantly after b12 injections) I haven’t had my folate levels checked recently but they were 8.0 about a year ago. Also a recent blood film examination revealed occasional atypical lymphocyte.

Incidentally, I was also diagnosed with a Multinodular Goitre about 18months ago which my Metabolic Specialist says I am borderline thyrotoxicosis. My recent TSH levels have been 0.31 - 0.58 and my serum thyroxine 20.9.

I would so appreciate your thoughts on this. Do you think any of these results are attributing to my feeling so unwell.

Many , many thanks.

Written by
UnitNitrogen73 profile image
UnitNitrogen73
To view profiles and participate in discussions please or .
Read more about...
7 Replies
JanD236 profile image
JanD236

Please could you post the range for each of your blood test results as this will be helpful.

UnitNitrogen73 profile image
UnitNitrogen73 in reply toJanD236

Hi

Thanks for getting back to me. I appreciate it.

MCV range 83.0 - 101... although on b12 deficiency.info it states the range use to be 80-94 and they advise anyone above 94 should be checked for b12 deficiency

MCH range 27 -32

MCHC range 310 -360

Homocysteine range..... Lab results state...desirable levels up to 10.0

TSH range 0.27 - 4.2

Serum free T4 ... 12 -24

Zinc range 11-24

Serum creatinine....range 44 - 80

Potassium range ....3.5 - 5.0

Hope this is helpful..... it would be great to come up with an answer 😄

Many thanks

Marz profile image
Marz in reply toUnitNitrogen73

Your Thyroid test results really tell you very little. A multi-nodular goitre could suggest Hashimotos - and from the results you have posted - you have not been tested. You need the FT3 result - and not just the FT4 - along with the Thyroid anti-bodies TPO and Tg to rule out Hashimotos.

The NHS rarely if ever check the FT3 - the most important Thyroid Hormone and only test one anti-body - so pretty useless in establishing the cause of your unwellness.

Hpome Testing kits available through Thyroid UK - and used by 1000's on the Thyroid UK Forum in order to have the complete story.

thyroiduk.org

Click onto the above link and then ABOUT TESTING on the Menu to find the companies offering Private Testing. VitD result ? - 2500 IU's supplement maybe too little ! Co-factors being taken ?

UnitNitrogen73 profile image
UnitNitrogen73 in reply toMarz

Hello

Many thanks for your reply. I will certainly look into the thyroid problem.

Marz profile image
Marz in reply toUnitNitrogen73

As mentioned above the NHS testing is not adequate as it fails to test the important bits ! So good luck !

fbirder profile image
fbirder

Your blood work all looks fine to me, although I know nothing about the thyroid stuff.

Your homocysteine is well within the normal range.

Potassium levels only drop for a short time after B12 supplements have started following a severe case of macrocytic anaemia.

UnitNitrogen73 profile image
UnitNitrogen73 in reply tofbirder

Hi

Thanks for your reply. I appreciate it. Just hoping I could come up with an answer..... onwards and upwards.

Many thanks.

Not what you're looking for?

You may also like...

Blood tests advice please

Hi I recently had blood tests repeated after dr has withdrew my injections (last one was in...
joleen19832 profile image

Asking a couple of questions- thank you ☺️

Hi everyone and thank you for having me. New here .. I have a question.. low B12 lots of bad...
Rex2020 profile image

Advice please!

Hi I am hypothyroid and normally use the Thyroid UK part of this site. Just recently I have had...
Tweetypie28 profile image

Testing for Functional B-12 Deficiency

Is there a testing method that has been shown to be accurate for determining functional B-12...

B12 treated but anemia no better

4 months ago I began B12 injections (methyl) for my B12 deficiency with macrocytic anemia. I've...
etreas profile image

Moderation team

See all
Gambit62 profile image
Gambit62Administrator
Foggyme profile image
FoggymeAdministrator
taka profile image
takaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.