I went to the doctor about 3 months ago with a number of symptoms. They'd all just been adding up and I was convinced there had to be something going on. I was almost relieved at first when I was told there was in fact a possible cause for it all, B12 deficiency...
I had some blood tests and was initially very impressed by the variety of tests the GP ordered. Came back with low B12 (162) and so this was investigated further with a follow up B12 (170), and other tests to determine the likely cause including coeliacs, intrinsic factor, MMA, homocysteine, etc. (I've never been vegan or vegetarian so thats ruled out straight away.)
This time nothing positive to indicate the cause, although I understand the pernicious anaemia assay can give false negatives. Nevertheless I was given the standard loading doses of hydroxocobalamin at 1mg/ml 3 times a week for 2 weeks. Initially I didn't notice much difference, but about a week afterwards I felt back to my old self and amazing!
The annoying thing is that the effects only lasted for about 2-3 weeks, at which point I crashed and felt like I had gone back to square one again with extreme tiredness, agitation and negative mental mood.
I've seen a few GPs at my practice now and the answer I keep getting is that the BNF advise repeat injection frequency of every 2-3 months which they refuse to budge on, regardless of my symptoms returning in full!
I've read quite a few people saying they have their injections more frequently. So my question is have you managed to get this approved by your GP somehow? I've also learnt that self-dosing seems to be what a lot of people are doing in this situation, but being new to this I feel like I want to keep trying with the doctor for a while longer.
Another question I have is are there other people out there who have B12 deficiency but don't know the cause?
I've found reading other posts really helpful so far and to know there are so many other people in this situation. Its all new to me so any thoughts or advice will be greatly appreciated! Thanks all!