He members, I have read much about an exaccerbation of B12 deficiency symptoms after starting B12 injections to proactively readdress B12 deficiency, but wondered if anyone here has experienced improved energy and reduced brain fog the day after their first injection, as I have?
I don't have severe neurological impairment as other have when starting B12 deficiency treatment, but I am acutely aware of how I feel and function - I'm particularly 'self aware'. My biggest issues are chronic fatigue, brain fog and GI issues.
Following my first B12 injection on Friday, which is the start of a 3 month B12 trial therapy for "non-autoimmune functional B12 deficiency", I didn't expect to feel an improvement straight away, however, yesterday I awoke a bit fresher and had marginally more energy and a more positive outlook. My family noticed a difference in me and I was more focused and smiley! I fell asleep for 2 hours in the afternoon, which isn't typical, and awoke okay, had a rough night with poor sleep (only 5-6 hours and of dubious quality), but again, I awoke reasonably okay this morning and took my first solo injection with ease. I have had the very occasional sharp pain in my head and my appetite is slightly lower, but then I actually feel like I have fuel in my body after eating, rather than feeling I'm running on empty all the time, even after eating, which is another positive!
I recall feeling a similar way the day after acupuncture for chronic fatigue about 6 years ago.
How soon can a person with B12 deficiency respond to injections and how often do people feel worse before they feel better? Is it typical to feel there is an improvement in energy/brain fog so soon after starting B12 injections?
What are your experiences after starting frequent B12 injections?
Thank you!
Written by
Beccy_123
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I think it varies so much. It will also depend on different factors - root cause, how late it was found, if its PA or another cause.
While I felt some relief initially, it took a very long time to really get the benefits. In very deficient people levels need to get high very quickly and so every other day can do this and often repair the damage.
Other people are still very unwell after loading and need more.
I experienced a lift in brain fog and enhanced smell and taste within a day of taking 750mcg of methylcobalamin tablets. But I found symptoms returning if I didnt keep dosing, eventually into the 5k to 10k range. new symptoms appeared after starting injections, including much sharper nerve pains like electric shocks and a dramatic reduction in muscle strength, worsened aphasia and memory problems. The muscle weakness only improved very slowly over many months and is still a long way from "normal" - my muscles always feel like they just ran a marathon. The nerve pains also improved slowly over months but have not disappeared.
could you expand on the aphasia symptoms from the b12 injections ? I believe I am experiencing the same thing but am not 100% sure. If its ok, could you explain the situation/worsening of the side effect ? It would really help, thanks
It began with mixing up words or skipping words while typing but not noticing it was happening until I went back and read what I had typed. This still happens but during the treatment period it started to happen in my stream of consciousness and also in my speech (using the wrong word in place of another). I'm not sure its improved much, maybe a to a very small extent, but it still annoys me frequently.
So encouraging that the injections are helping so quickly! I don't get worsening symptoms as some report. I too get an immediate relief from a few symptoms. My vertigo stops and heart" flutters" stop. The body buzzing/vibrating reduces considerably. I am much less clumsy. Increase in energy starts second week after. I have only had 2 shots of cynacobalamin 30 days a part. So I am really just getting stared. Symptoms start returning after 2/3 weeks . When I have my follow up appointment, I will try to get my Dr to increase the shots to every 2 weeks. Just in case he refuses I have ordered ampules from amazon.de. I didn't get the same relief from tablets or oral drops. I am really hopeful about the shots. I hope your symptoms continue to subside Beccy_123.
My very first shot washed away the awful anxiety I had been feeling and gave a burst of energy. The rest of my symptoms took longer and some are still being resolved. After my third shot the tip of my nose no longer felt cold. My nose started to tingle and feel warm again.
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