Positive ANA and TSH 1.1. A Quick Que... - Pernicious Anaemi...

Pernicious Anaemia Society

32,672 members24,065 posts

Positive ANA and TSH 1.1. A Quick Question Prior to GP Appointment

Foggyme profile image
FoggymeAdministrator
13 Replies

Hello All. Blood tests in April showed a positive ANA (titre 1:40 homogeneous pattern), which my GP ignored. Another ANA test done by the gastrologist a few weeks ago also showed a positive ANA (titre unknown, waiting to go for full results). The gastrologist has written to my GP asking him to refer me to a rheumatologist and I am going to see him today to follow up on this.

Bloods for TSH in April were 1.1 (0.30 - 5.00 min/L). I am aware that this is not a very accurate test.

I'm still struggling with B12 (it appears to have stopped working) and it looks like something autoimmune may be going on but because of the cross-over symptoms, it's quite difficult to sort out exactly what!

My questions are: would it be reasonable and appropriate to ask my GP to run a full thyroid screen and a full adrenal panel? And is there anything else that I could reasonably asking him to test, prior to further hospital appointments?

Many thanks

Written by
Foggyme profile image
Foggyme
Administrator
To view profiles and participate in discussions please or .
Read more about...
13 Replies
Withattitude profile image
Withattitude

I think that considering all of your symptoms and the pain you've been in, it is more than reasonable to ask for a full thyroid screen, adrenal panel and anything else he's willing to test. Are you still injecting b12? I would also ask for MMA and homocysteine, as you still have symptoms. I'm not sure if high levels of b12 will impact on these, but if it's anything to do with functional deficiency I would have thought they'd still be high.

I'm so sorry you're going through this Foggyme and I hope you get some answers soon.

Withattitude profile image
Withattitude in reply toWithattitude

You might also like to consider genetic screening too.

Foggyme profile image
FoggymeAdministrator in reply toWithattitude

Hi with attitude...many thanks for your quick response.

First, yes, still injecting B12, but any improvement is only very minor. Now thinking of reducing the dose to see what happens....if that fails I'll do what Gambit did and try nasal drops. It's a minefield isn't it....more or less B12 is a tricky question, especially with increasing neuro symptoms!

I'll go ahead and ask for the full thyroid and adrenal panels, but whether they agree remains to be seen. Sometimes I just can't fathom how a GP can see a patient reduced to the point of near collapse on a daily basis and not want at least explore all the options! In fact, do anything at all!

If I have no luck with the GP, I'll get the tests done privately but my goodness, this is getting expensive!

I saw a neurologist recently and he has done MMA and homocysteine....(and a head / spine MRI) so just waiting (and waiting) for the follow up appointment.

And good idea about the genetic screening. Funnily enough, I'm going to Leeds tomorrow to see a functional medicine practitioner and that's one of the things I'm going to explore.

Anyway, thanks for your advice...I'll let you know how the GP responds!

Take care xx

Withattitude profile image
Withattitude in reply toFoggyme

I went to see a private GP, who does all my tests through the NHS. When I thanked him, he said I was entitled to care. He's lovely, doesn't have a clue what's going on, but he cares. I wonder if you could find someone similar. Hope your appointment goes well on Wed. It might be worth a call to your neurologists secretary to see if they have test results back. I so want us both to find an answer. :)

Foggyme profile image
FoggymeAdministrator in reply toWithattitude

Oh yes indeed...me too! I think I'd love to have a GP who cared...even if clueless...at least there would be enough interest to try and find answers (if there is any such thing!).

Will chase neuro next week if I haven't heard anything.

I'm not a whimp but oh how I hate going to visit my GP 😖.

Will let you know how it goes x

Withattitude profile image
Withattitude in reply toFoggyme

I hate visiting my usual GP too. Good luck :)

Foggyme profile image
FoggymeAdministrator in reply toWithattitude

Hi Withattitude. GP done! Discussed positive ANA and yes, definitely something going on with autoimmune system. Quite funny really 'cause as I went through list of test I wanted him to do, he went sort of 'blank'. It was only when I said that this had been going on for 16 months and it was time to start ruling things out that he decided to refer me to both a rheumatologist and an endocrinologist...so, good out come. I'll get the tests I need...just have to wait a little longer!

I did laught at myself yesterday...having posted the question, I knew what I would have replied to anyone else posting the same question....but I'm just such a wuss when it comes to myself!

Thank you so much for your support...kept me strong in the face of resistant GP 😀.

Will let you know outcomes.

Take care xx

Withattitude profile image
Withattitude in reply toFoggyme

Hello there. So glad you got a good outcome from GP. I got my genetic test results and I do indeed have a problem with processing b vits. Not sure where this is going to lead, but will let you know. I hope you have a really good meeting this afternoon. Functional medicine rocks in my eyes and do keep me posted. I'd love to know how you get on.

We can do this! :)

Foggyme profile image
FoggymeAdministrator in reply toWithattitude

Thanks Withattitude...yes, I'll keep you posted.

Already decided that I'm going to go for the gene testing...wouldn't be surprised if I also have a processing problem!

We can do it indeed...watch this space...

Many hugs 😀

Withattitude profile image
Withattitude in reply toFoggyme

👍

ndodge profile image
ndodge

Good luck with it all foggyme! I hope and pray that you get a really good doc who can tell you what's going on. My money is on the functional doctor.

The B12 was helpful for awhile, right? Did it help with all of your symptoms? It is so strange that it stopped working.

Best wishes for answers. I want you to feel like a million bucks, stat! :-)

Lots of Hugs xxx :-)

Foggyme profile image
FoggymeAdministrator in reply tondodge

Hi Ndoge and bless you...feeling like a million bucks would be marvellous...stat or otherwise 😀.

GP done. Eventually agreed to refer me to both rheumatologist and endocrinologist (see reply to Withattitude, above).

Yes, the B12 was helpful for first four years...though like many, I never had enough and always ran out about 4 - 5 weeks post jab and limped along until the next one (what a familiar story).

Strongly suspect that something else is going on in the autoimmune department so hopefully endocrinologist and rheumatologist will come up with something...not so much botherd about getting a 'label', just something that will point to a way of getting these nasty little symptoms under control (another familiar story).

Off to functional medical practitioner later today (3.30 over the pond time) so very interested to see how that goes. I suspect (know) that she is more knowledgable about all thing B12 so will be very interested to see what her take on this is (incidentally, she was one of the speakers at the B12 conference at Loughborough University, this summer).

This is a long journey, I think. Feel like I've been standing at the diagnostic bus stop for far too long...what's the betting all the busses arrive at once! Or at least, here's hoping...

Take very good car Ndodge and I'll let you know how it all goes.

Love hugs and everything xx

ndodge profile image
ndodge in reply toFoggyme

Hi Foggyme, my pond friend,

Loved the line about the diagnostic bus stop! May all the buses arrive in good order to take you on the road to recovery- hopefully an express bus :)

I'm so hoping the Functional doc can help you feel better and get to the bottom of this! You must have seen her by now with the time difference. Its very impressive that she was a speaker at a B12 conference- hope you come away with loads of good info and some real help!

x hugs x and love xx from my lily pad to yours... :)

Not what you're looking for?

You may also like...

letter to GP and question

I haven't posted in a while, I have really been through hell. The GP is just not listening to me....
Cazzie91 profile image

Seeking advice prior to GP visit (low B12 test)

Hi, Only recently found this forum but it looks like a very useful resource so I can see I'll be...
GavinUK profile image

GP does not do loading dose as per BNF guidelines due to pressure on appointment availability !1

Hi all, Finally had a reply from my letter to GP questioning why my loading dose of 6 jabs was...
Barry1955 profile image

No longer B12 deficient? No cause found. Advice needed.

Hi all, I’m new here and not even sure if this is the right place to seek some advice from others...
Geppers profile image

GP stopping my B12 injections despite a positive intrinsic factor antibody result

I was diagnosed with rheumatoid arthritis in 2007. In 2010 I suffered a numb tongue and extreme...

Moderation team

See all
Gambit62 profile image
Gambit62Administrator
Foggyme profile image
FoggymeAdministrator
taka profile image
takaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.