I had a positive IFA and PCA blood result last November. GP gave me a leaflet about PA and told me I had PA and would nd treatment for life, although he said my B12 level was not low at 348 and other bloods were ok. He gave me 1 jab as a trial, which did nothing, so I joined PA Society and went back asking for loading doses based on alternate days until neuro symptoms stopped improving. GP stated they only give 6 jabs over 3 weeks, so accepted reluctantly. GP said he wanted me to see a Gastro Consultant for further information, and also took a second PCA blood test which was again positive ( lab said no need to re-test IFA )
Outcome of Gastro visits was a Gastroscopy which showed Chronic Gastric Atrophy but no other issues on camera. Result of biopsy showed H.Pylori present ( successfully treated ). Gastro did another PCA test which came back negative, so was discharged back to GP stating no evidence of PA , totally ignoring my positive IFA result, and advising I stop selfinjecting which I started before seeing Gastro with vast improvements in my neuro symptoms ( still get intermittent tinnitus ).
I had been on PPI`s for over 10 years , to protect my stomach from all the meds I was put on due to Heart Disease, which I no longer take. I have put a letter on my GP records stating I will continue self injecting as no one can tell me why I had a positive IFA result, and all info states a positive IFA indicates Pernicious Anaemia.
My confusion is has the presence of IFA caused the H.Pylori infection, or has taking PPI`s caused the H.Pylori leading to the IFA positive result ?