Mother Diagnosed with Stage 4 OC, recurrence, now liver traces

[akhilsalwan]

Hi everyone, looking for advice/suggestions:

My Mother currently fighting stage 4 Ovarian Cancer recurrence (high grade Serous Carcinoma) first diagnosed in January 2022. Started Chemo in Feb, 2022, got a Full Hysterectomy surgery and received Hipec chemotherapy, was free of cancer by August only to realize cancer came back in December 2022.

Several rounds of chemotherapy during recurrence with slight improvement and then chemo didn't respond. Moved to Oral Chemo for three months which didn't work and CA125 went from 55 to 310 in three months of testing IV and Oral Chemo.

Recently onco advised Paclitaxel weekly for 6 sessions and bi weekly for another 3 and CA125 reduced to 230 (100 points reduction) after 4 sessions and after 6th session CA 125 only reduced to 210 (20 points) however the Bilrubin level in Liver went up from 0.25 to 5 in a span of two weeks, extreme fatigue, tiredness, loss of appetite. Got a MRI scan and the liver doctor said her Chemo is not working over the Lymph node near Liver and they can see several traces in/around liver.

Very stressed with this latest information as we thought the Chemo is helping but it wasn't. Onco and every other doc is saying to fix the liver situation first before any other treatment can be done. Any advice thoughts on what can be done next if anyone has been in this situation before? Mother recently got a stunt in the liver to remove the blockage and saw slight improvement in levels.

What other alternate treatments can be taken?

What about Elahere or Olaparib?

Can CBD or RSO oil stable the situation?

Please help looking for advice/guidance.

[Lyndy]

Hello, I am sorry to hear that your Mother is in this situation. You must all be worried.

Chemo, whether it works or not is very rough on the body, so getting her liver to a point where she can take further chemo is sensible. Have they said what they might do to make this happen?

All the best xx

[NanB12]

Hi:

I am so sorry to hear about your mother. Please stay positive and don’t give up hope. Please ask your doctor about tumour testing to see if your mom will qualify for immunotherapy. Also a plant based diet has been very helpful for me, to reduce inflammation in the body. All the very best to you and your family in this very tough journey.