What Next?

[27-359]

I have been on this forum for a few years now, and have seen that treatment usually follows the same procedure.

I have had Carbo/Taxol with Avastin, Carbo/Caelyx, Rucaparib and am now ready for the next goody bag.

Single Taxol has been suggested, but I have heard that this is not very successful. Does anyone know differently? I believe I could also have single line Carbo or Caelyx. Any thoughts on that?

As I am oestrogen positive, Anastrozole is a possibility. This is an unknown to me, so I should welcome hearing from anyone who has had this.

Jenny

[delia2]

Hi. So it sounds like you are still considered platinum sensitive? Some people have carbo and gemcitabine/gemzar as their third chemo cocktail. I don't know how that compares to weekly taxol but my impression is that weekly taxol is quite effective, the main drawback being you lose your hair and it's every week. It's good you have options. Maybe try the estrogen blocker first and see if it works or what about a trial? Is second surgery a possibility? Good luck and keep us posted. I will probably soon be in a similar situation. I've been on olaparib for twenty months but I keep getting twinges in my abdomen. Hopefully they are not cancer related. xx

[27-359 in reply to delia2]

Thanks for replying. Yes, I am considered platinum sensitive still. I don't think more surgery is possible, as I have modules in my lungs nowI am waiting for a Dexa scan as I think bone condition might rule out the Anastrozole though it is tempting to try that first if I can still have the chemo later.

Jenny

[SUE7777]

Hi Jenny, I'm on weekly Taxol and it's definitely working as I don't have ascites which I did have when I was on Caelyx/Carbo which didn't work for me so I am platinum resistant now. It's great to have options but difficult to know what to choose. All the best Sue xx

[27-359 in reply to SUE7777]

Thanks for that. How long have you been on the Taxol?

[SUE7777 in reply to 27-359]

Since October

[Ruebacelle]

Hi. My understanding is that taxol is the gold standard for oc. I had it weekly for 7 months and it wiped out most of the cancer. Make sure you get booster shots for the white cou t. Car o is also successful if you are still Platinum sensitive. Hugs from Paris

[27-359 in reply to Ruebacelle]

Thankyou. It's reassuring to hear that it's working for you.

[Maus123]

Hi Jenny. It's my (lay man's) understanding that Anastrozole is a drug in the same category as Letrozole - an aromatase inhibitor that reduces the amount of estrogen produced by the body. [pls check with your medical team though, as I'm only an IT person and might get the details wrong ]My OC type is serous low-grade, which might also be hormone receptive (never seen a lab test result for it but it looks like for low-grade OC it's not unusual to be hormone driven), and I take Letrozole daily to try and delay the next recurrence until the cows come home (or until I'll eventually catch and succumb to a popular disease caught from too many neighbours unwilling to get vaxxinated against, hrmpff ).

If Anastrozole works for you, it might be one of the lower impact treatments. So I wish you the best of luck with it! xx. Maus

[27-359 in reply to Maus123]

Thank you. Interesting to hear about your experience of Letrozole. I am hoping to hear from someone who has had some success with Anastrazole.

Jenny

[Maus123 in reply to 27-359]

Apologies, my bad, as I haven't actually taken Anastrozole myself (yet, as it's been offered to me as an alternative to Letrozole if needed).

[Rosebud4004]

hi all I'm new today. I've had two recurrences with my last chemo finishing in March last year. I'm now on niraparib and it's going well after the first couple of months of nausea. I wanted to share my success with everyone. I've bought Jane McLelland's book 'How to starve cancer' and have completed her online course. I have now changed my diet - cut out all dairy, sugar and saturated fats with some vegetarian days. I also take a wide range of supplements. It was hard work to work out which ones to use but the online course made it clearer. I also take a range of repurposed drugs which I get prescribed by the Care Oncology Clinic, as recommended by Jane. The great news is my last CT scan showed that I have 2 areas of disease left, down from around a dozen. But the brilliant news is the one sitting next to my kidney is stable and the other one in one of my lymph nodes has reduced in size by 50% in 3 months! It seems I am doing the right things and am determined to not have another recurrence! Good luck ladies.

[Petrolhead in reply to Rosebud4004]

Hi Rosebud4004- I think Jenny was asking for people who had tried Anastrozole. You maybe better sharing your general post as a new thread.

Best wishes

Fay