I was diagnosed Nov 2014 stage 3 and since have had usual major surgery. I have had 4 lines of chemo: carboplatin/paclitaxel, Carbo/caelyx, weekly paclitaxel, carbo/gemcitabine, but have never managed 6 months of remission inbetween new chemo.
Recently CA125 has risen to 1330 (Nov) dropped to 1093 (Dec) and now rising in March with CT scan showing progression of disease. Carbo/gem treatment has been stopped after 4 cycles as deemed to be ineffective. A phase1 trial has been discussed but after screening etc I am in effect 'too well' as tumours are too small and it appears that there are no suitable phase 2/3 trials. There is reluctance to continue treatment although it has been suggested that one chemo without carboplatin could be tried as I am resistant to carboplatin, known as 'platinum refactory' although 'response rates from subsequent standard therapies are low' . It has also been mentioned that I have a high level of oestrogen so a hormone drug might be effective. Has anyone had endocrine therapy? and what results /side effects?
Whilst I feel well and lead a reasonable life, I know that the disease will progress rapidly, and I am not ready 'to go'. Has anyone else been in tis situation?