I started 3rd line chemo with carboplatin/caelyx eight weeks ago. I never got to the 2nd cycle because all hell broke loose in my bowels. Gripes, stoppage, violent uncontrollable diarhoea in that order over a couple of weeks then finally a fistula so I am in nappies stuck between bed and loo awaiting a multidisciplinary team decision about what to do next. This will probably be surgery. Meanwhile my CT scan shows that the tumour has begun to invade my bowel in another place. I will probably be prescribed chemo again when the fistula business is resolved and am now terrified of caelyx. What experience have others had with caelyx? and what are the alternatives for 3rd line ? I daresay my onc will put it down to coincidence but it is not a coincidence I want to repeat ! Any experience or suggestions will be very welcome. I feel very alone with this ! I was so full of energy a few weeks back until suddenly wham! full invalid status and can't see the light at the end of the tunnel.