Yuflyma -Adalimumab

[Lucena62]

Hello, I posted a while ago as I was taken off Rinvoq in September due to elevated liver enzymes. Had a 3 month Kennalog injection in October due to a serious flare up that left me bedridden and unable to walk for a week.After a raft of blood tests, MRIs, Xrays and CT scans I was told by Rheumatologist that she wasn't sure what to do next as I needed DMARDs but having been through everything from Methotraxate, to biologics to Rinvoq there wasn't much else left to try and due to liver damage results I was excluded from lots of options. She wasnt in favour of steroids and steroid injections as an option either. I left that appointment feeling very scared and frustrated.

I saw Rheumatologist again just before Xmas and she said she'd like me to try Yuflyma which is a new biosim of Adalimumab, didnt have a great experience with Humira but I've agreed because there really isn't any other option on the table.

I'm just awaiting delivery, has anyone else taken it and if so what results and side effects etc?

Many thanks in advance

[virtualreality]

Hi Lucena62 , I'm so glad to hear a suitable treatment option has finally been found for you, what a relief that must've been after the earlier conversation with your rheumatologist.

I've heard about many people getting great results with Yuflyma, sometimes within a couple of doses, so hopefully that'll be the case for you. I've tried it myself and while it wasn't the answer for me personally, there were no problem side effects and I did appreciate the doses being only fortnightly! The injection is low-volume and citrate-free, so non-stingy and much more comfortable than many of the others. Fingers crossed you'll get a good result 🌼

[Lucena62 in reply to virtualreality]

Thank you VR, I'm hopeful and will try anything. The Humira worked for the RA but my back came out in a mass of varicose and red spider veins which was odd and scary.Hope you found something after Yuflyma

Xx

[virtualreality in reply to Lucena62]

Oh goodness that does sound scary, perhaps it was something specific to the Humira formulation and Yuflyma will be different. Not sure on my next step yet, might be rituximab but we're waiting for a test result to clarify - hopefully it'll come through soon x

[Lucena62 in reply to virtualreality]

Hope so, we suffer so much in between medications

[Miasnana in reply to virtualreality]

I also was switched to Yuflyma and I have to agree that it is very much less stingy than my previous bio-similar. Still not sure it is working as well, but have decided to give a go for a bit longer. I hope you finally get one that works for you.

[virtualreality in reply to Miasnana]

Thank you, it is a complicated process sometimes, isn't it! I hope you get a good result with Yuflyma in the end - I didn't see any effects at all until 4+ months in, so it seems it can be quite slow to take effect sometimes.

[Lulla]

hi I’ve been on it for a few months and no side effects so far

[pammi2]

sorry to say i took it for 5 months and it did nothing for me, i took about 11 doses.

[pammi2]

the only side effect i felt i had was i felt like i lost hair.

[RainbowLeopard]

I started it in November. Since far its been great, no side effects and I think it's having an impact. Hope it works for you

[Tealblue2]

hi. I’m on it. I have been since June. After about 5/6 weeks I really started to notice an improvement. It’s taken a long time for me to get well, they have subsequently added leflumide and my yuflyma injection is now weekly. With 2 months of that I am getting there now. 🤞🏻it stays that way (it has all come undone this week thanks to norovirus, but that’s another story!)

I do notice that the day after my injection if I’ve had a busy week then I find I am quite exhausted and need a good rest. But start to feel better by lunchtime if i take it steady. Other than that all good.

Wish you luck

[oldtimer2]

Have you been on azathioprine? I find that many rheumatologists have forgotten about this useful DMARD. Although if you can find a biological treatment that suits that would be even better.

[Lucena62 in reply to oldtimer2]

No I haven't but good to have as an option. Over 13 years I've had methotraxate tablets, methotraxate injections, sulphalzine, leflunomide, several biologics and DMARDS

[Happy5]

Just been put on this alongside MTX which I've taken for over a decade. Started 23 rd December had my second lot so far so good. Was nervous about starting it, was supervised via video for first time which was fine, nurse was lovely.

All the best let us know how you go?

[WilfDog]

So glad you have been given another option, especially after your initial consultation. I hope and pray this works for you. I haven't tried it myself but from what others have said there is a positive response with many.

I have everything crossed for you xx

[Lucena62]

Thank you Wilfdog, it's been a very troubling time and the thought of living without any dmard support is scary, the Dr has high hopes so we shall see. I got the green light on 23rd December but no sign of meds yet, I can feel the Kennalog is pretty much at the end of it's run so will be chasing tomorrow.Will keep you posted on progress

[Lucy999888]

I’ve been on it for 3 months and it is easy to use and that comes from someone who has a fear of needles! It is an injectable pen, so that’s good for me. I’m still in two minds as to whether it is for me, but carrying on for a bit to see. Hope it works for you.