New Meds

[mattcass]

Hi There, Has anyone been on or used UPADACITINIB it came out on Jan 2021 I'm starting it soon but only if The Freeman Transplant Team give me the go ahead they are checking on it just but need more info about, Matt

[Wobbies]

Never heard of it but good luck.

[Neonkittie17]

I read in August it had been approved here in the U.K., a little behind Europe and USA. I only know it is a JAK and for moderate to severe RA. I hope it works well for you.

[Mmrr]

I think someone posted a few weeks ago saying they were about to start it, you may find the post in the search box.Good luck with it.

[ElizabethW]

It is a JAK inhibitor also kmown as Rinvoq. It is a once a day pill. I have been taking it for 6 weeks now, after a horrible year of trying 2 other JAK's and a biologic that didn't work for me. At this point it probably has not reached its full effect for me, but so far it works much better than either baracitinib or Simponi, and without the terrible side effects of Xeljanz.

Most of my problem joints feel much better, and I am still hoping to see improvement in my right elbow and shoulder which are still giving me a lot of trouble.

For over 6 months, my ESR and CRP remained sk,y high, but last week I had bloodwork done and I just about fell off my chair when I saw that my CRP was 0.6! Other values are also improving.

I have not had any illness or infections. I am feeling optimistic about this medication and hope that things keep getting better.

It seems that different treatments work for different people. I hope you do well with this drug. Good luck.

[Neonkittie17 in reply to ElizabethW]

👏🏻 That’s excellent news. 😃

[ElizabethW in reply to Neonkittie17]

Thanks.

[mattcass in reply to ElizabethW]

Thank you Elizabeth. matt

[hatshepsut]

I have just started it. First week, no ill effects. Too early to notice improvements, but am keeping fingers crossed.Nice to hear from you...... how are things?

[Neonkittie17 in reply to hatshepsut]

Hope it works great for you. 🙏🏻💗

[ElizabethW in reply to hatshepsut]

I hope you do well with it. I started noticing small improvements after only 2 weeks. I haven't had any sudden dramatic effect, just gradual but steady easing of pain and stiffness in my ankle, feet, hip, left shoulder and elbow, hands, and jaws. My left knee and right shoulder and elbow are taking longer but I hope they will be better too.

[Madmusiclover in reply to ElizabethW]

Reading that list made me smile. I often start at the top (jaw) and work my way down to assess what is hurting how at any given time. Easier to think about what isn’t hurting! Good luck with the drug effects.

[Green230461 in reply to ElizabethW]

What a great pain shopping list! Do I know you? We could be related🎄

[Green230461]

I’m on baricitinib sounds similar! Best of luck to you let us know how you get on. It all adds to the Arsenal of information on here🎄

[SmithM52]

Hi, I began Rinvoq in early July after failing on baracitinib, another Jak inhibitor.Side effects were minimal & only lasted for a short time. It’s the best medication I have had in the last 25 years! Definitely helping all my joints & mobility. One hip is still being a bit stubborn but overall it’s been a game changer. Would definitely recommend. The other good thing is it’s quickly out of your system if you do have to stop using it.

[mattcass in reply to SmithM52]

Thank you sorry for the delay going through a bad time, I am trying to find someone who has had a transplant of some sort as I have had a Double Lung Transplant. Matt

[Hisue]

Rinvoq has helped my RA more than all the other meds I’ve tried over 8 yrs of having this horrible disease. It lowered my pain level, inflammation & reduced swellings a great deal. Was able to eliminate MTX. So much easier to take 1 Rinvoq tablet a day, than injs & MTX.

Only side effect was shingles about 8 weeks in. Stopped it & resumed after shingles healed. I’m doing pretty well again now - main problem now is still have major FATIGUE- hope it will be better after 6 months of treatment.

Good luck!