HI -- I've had RA for 14 years, diagnosed at 40. Have had a great partnership with Enbrel for over 10 years. They changed me on to Humira, an equivalent (as an NHS cost-saving). Not sure if that interfered with my condition, but suffered with swelling and pain, in every joint. This has been ongoing since May. They put me back on Enbrel, still with no positive improvement. Came off Enbrel as conditioned worsened, so started a new Biologic, Rituximab - two 6 hourly infusions, 2 weeks apart. This was supposed to last for 6 months. However, I have had no improvement whatsoever. They can't give me a new biologic until the 6 months is over (Jan), so I'm on 4 weekly steroid injections to tide me over. They are helping and I'm able to drive etc., but my consultant doesn't want to give me more that 3 of these injections.
I have been given 2 leaflets, so that I can choose which biologic to try next in January ! The two biologics are Baricitinib and Tocilizumab. Is there anyone who has had a similar experience and has responded well to Enbrel, had no reaction to Rituximab but success with Tocilizumab or Baricitinib? A long shot, but worth a try!
Cheers, Elaine x