I was diagnosed with IGAN in 2013. Back then it wasn't bad. Can't remember what my GFR was at the time but I felt fine and didn't take the diagnosis seriously at all. So 4 years go by and I decide I should probably at least get it checked up on. These are the results of my blood work from 5/17:
Protein, Total-5.6 g/dL
Bilirubin, Total-0.4 mg/dL
Alkaline Phosphatase-52 U/L
Anion Gap-13 mmol/L
eGFR- 47 ..
Now in December my glucose has risen to 111, BUN is up to 26, Creatinine is up to 1.94, and my eGFR has decreased to 42.
The Nephrologist has had me on ramipril 10mg for BP (usually around 140/90), just started me on Lipitor, and today started me on Prednisone.
And now for the reason i'm writing this post. They want to start me on Cytoxan which is a potent chemotherapy drug used to treat cancer and in my case could be used as an immunosuppressant. But the side effects are scary. A few are hair loss, nausea/diarrhea, ulcers, infertility (i want to be a father someday), extreme fatigue, and an increased risk of developing certain cancers like leukemia.
So, in the past year my GFR has dropped 20 points. While I know there's no way to predict the rate at which my function will decline the math suggests I'll be in end stage kindey failure in 2-5 years. While I understand the cytoxan will probably slow the decline is it worth the side effects? Especially if kindey failure is inevitable?
I guess i just don't want to make a risky/hasty decision. Especially if there are other treatments. For one my diet is absolutely horrible and I barely exercise. I'm not in bad shape (BMI is 28) but there is ALOT of room for improvement and I think I want to try that before chemo. What do you guys think? And does anyone know any other non-prescription methods for improving kidney function? Thanks in advance!