HCST

[cnichols]

Has anyone looked into doing stem cell transplant? My neurologist told me that they wouldn't accept me because of my age 48 and because I have had MS for 9 years, think I want to try, this disease is so frustrating.

[erash]

cnichols ive read really good things about HSCT. Albeit some potential side effects the results sound very promising. I don't think it's being done in the US ...unless in a research study?

[HSCT2016 in reply to erash]

Yes I had it in chicago as part of a clinical trial. Check out clinicaltrials.gov to find one

[Jesmcd2 CommunityAmbassador]

Hi cnichols the person you want to talk to about that is 1RiskyRich . He has had it done and has only good things to say about it.

But as erash said l don't think it's done in the States and personally ldk much about it.

Jes🌠

ps. If you put in HCST In the search box you will see other discussions we have had.☺

[Miriade]

Hi, I watch a program on TV, not paid program, probably from Public TV station. Someone from Texas explained in a interview how he could be finally heal fro MS doing the Stem Cell, with American Doctors, but in Guatemala. It tooks over a year, and he is walking and back to work.He is in the 40ths age. The couple was little scar at the beginnig going out of US, but he and others patients had the improvement not able in US. I know they also do in Canada, but rhw results vary depends of the patient. I read reports and statistics about

And there are three differents procedures in Stem Cell Therapy.

[HSCT2016 in reply to Miriade]

There are several countries that perform HSCT at various costs with varying protocols. If you go to facebook and look up HSCT you will find a lot of groups with info. I had it in Chicago and I'm doing great. Canada only treats Canadian citizens.

[GasLight]

My level of understanding regarding aHSCT is pretty limited.

I do believe that aHSCT uses the patient's own mesenchymal stem cells (collected from bone marrow), idea being that these undeveloped MSC's haven't yet acquired the flaws that trigger MS. After harvesting and storing his/her MSC's, the patient's "bad" immune system is destroyed using chemotherapy, and the thawed-out stem cells are thereafter re-infused, (effectively re-booting the immune system back to a time point before it caused MS).

From what I've seen, study results appear to be promising: in the most recent that I'd heard about (123 people with relapsing-remitting multiple sclerosis), aHSCT was linked to about 65% reduction in average disability.

I also believe that Northwestern (Chicago) and Fred Hutchison (Seattle) are each doing aHSCT procedures for MS now (see the-irf.org/autoimmunity/ho....

As you noted, however, this treatment does not appear to be suited for everyone. I think that aHSCT only works for relapsing forms of MS, and that it is most effective for young sufferers who are still fairly ambulatory. It also is a pretty aggressive procedure, with obvious risks.

Here's an interesting survey piece that I came across a while back, that offers a good survey of MS stem cell research generally, key areas of development and anticipated trends. medscape.com/viewarticle/85...

Beyond aHSCT, it seems as though stem cell transplantation and treatment therapies will remain a hot topic, and that related work will soon move to embryonic stem cells, umbilical stem cells, etc. See generally hsci.harvard.edu/multiple-s...

As also seems to be occurring in other research applications, these developments undoubtedly will present the MS community (both collectively and individually) with increasingly wide moral, ethical and Spiritual hazards. See, e.g., sciencedaily.com/releases/2...

Blessings,

-- Christopher

[Jesmcd2 CommunityAmbassador in reply to GasLight]

Ugh. C. GasLight you do know l have to do out web sites don't you? 😕😅

[HSCT2016]

I had HSCT in Chicago as part of Clinical Trial. Chicago accepts up to age 55. I'm so glad the word is getting out! I've improved so much. I also have a blog elliehsct.com feel free to ask questions.

[KATC1972 in reply to HSCT2016]

Thanks for your posting! I'm 44 and am having trouble and was going to research this! I'm in Virginia so Chicago would be doable!

Take care

Kathy

[cnichols]

Sent e-mail so we will see what they say