anti-inflammatory drugs

[Trainer12]

I need an anti-inflammatory and I am on aspirin so can only take tylenol/paracetamol normally. I am currently in America, does anyone know of any anti-inflammatory drugs I can take while on aspirin?

[hunter5582]

Technically, you can take NSAIDs while on low-dose aspirin, but it increases your risk of hemorrhage. You have to do a risk-benefit analysis of your situation to make an informed decision. This requires expert medical consultation.

I have taken both 800mg Ibuprofen and 10mg Meloxicam under doctor's orders/monitoring while in aspirin. It did increase my bleeding/bruising to some degree but not too much. I discontinued the NSAIDs that I was using to treat osteoarthritis because I found something that worked better. My rheumatologist suggested I try curcumin. Not only has curcumn worked better to control the arthritis inflammation/pain but it does not potentiate the asprin to the same degree. I do not notice any increase in hemorrhage due to the curcumin.

Unfortunately, most doctors are not familiar with complimentary health interventions like curcumin. That is why I now consult with an Integrative/Functional Medicine doc. She provides expert consultation on the supplements i consider using and is knowledgeable about interactions with meds. Suggest expert consultation is a very good idea, particularly if you have a MPN. Here are two lists.

fonconsulting.com/resources...

ifm.org/find-a-practitioner/

Unfortunately, systemic inflammation is something we have to deal with. It is one of the consequences of having a MPN that deregulates the JAK-STAT pathway. I am glad I have found something that works for me. Wishing you success as well.

[dladydi in reply to hunter5582]

I am very excited to read this because my twin brother swears by curcumin but I have reluctant to use it. Now I am feeling more comfortable to give it a try. Thx again Hunter.

[hunter5582 in reply to dladydi]

Curcumin is definitely worth a try. Note that curcumin does not readily pass into the bloodstream. Some forumations are worthless. Be sure to select one that is bioavailable, I use a liposomal formulation called CurcuWIN , that is found in various brands. Other formulations use piperine (black pepper extract) to make the curcumin bioavailable. Do be sure to let your care team know that you are taking curcumin.

All the best.

[william-Indo in reply to hunter5582]

Hi hunter,

Do you take extract curcumin or raw ingredient form (tumeric).

Thanks for reply

[hunter5582 in reply to william-Indo]

I take a turmeric-curcumin blend that contains a liposomal form of curcumin. CurcuWIN is available in various brand name supplements. I use the Spring Valley brand, which is available at WalMart. CurcuWIN is the formulation that my Integrative Medicine doctor recommends.

[Morris941]

My husband is having the same issue. He has recently been diagnosed with ET-CALR and is currently laid up in bed with what we believe is a prolapsed disc. He has had this on and off for years but since having his bone marrow biopsy has become more uncomfortable then a bout of physio has left him unable to function properly. As he is now on daily aspirin, the doctor is against prescribing any sort of anti inflammatory medication so he is now on codeine and amitryptalin for the pain. Whilst this is helping it is not taking away the internal inflammation. I did pop into Holland and Barrett but they were reluctant to recommend anything due to the ET. He is seeing a pain specialist in a couple of weeks but it has been an absolute nightmare.

[hunter5582 in reply to Morris941]

This is a difficult situation. It is a real balancing act to manage the ET along with the aspirin and back injury. It is possible to take anti-inflammatory meds while on aspirin but it comes with risks. It is a judgement call whether the benefits outweigh the risks.

Consultation with a MPN Specialist would be very important in this situation. Most doctors would not be familiar enough with ET and its management to give a fully informed opinion. Just in case you have not seen it, here is a list. mpnforum.com/list-hem./

It may also be worth considering consultation with an Integrative or Functional medicine doctor if your husband wants to consider complementary health interventions. I have had very good results from using curcumin for osteoarthritis. It works better than NSAIDs and does not seem to potentiate aspirin to the same degree that NSAIDs can. Note that anything that is biologically active enough to help you can also hurt you and interact with things. It is prudent to seek expert consolation. Here is a list if you are interested. ifm.org/find-a-practitioner/

Hope he is feeling better soon.

[mark382 in reply to Morris941]

I had extreme pain in my legs 2 weeks before Christmas. I could hardly walk as every muscle when it moved with the intensity of cramp. Tried paracetamol, co.codamol, Diazapam and oramorph. None touched the pain. Have physio and on Pregabalin. I also use ibuprofen gel at point of where I think the inflation. I'm on Aspirin and I also have asthma, so anti inflammatory drugs are a non starter. GP said he was happy for me to use ibuprofen gel as very little enters the blood system. Hope your husband gets better. Back pain is horrendous.

[hall2]

I use ibuprofen and I’m also on aspirin. But I also take another drug which reduces the risk of bleeds in the stomach etc.

[Oscarsboy in reply to hall2]

Are you able to mention what the other drug is please?

[hall2 in reply to Oscarsboy]

Yes it’s Lansaprazole

[Oscarsboy in reply to hall2]

Thank you, I do have this already.

[hall2 in reply to Oscarsboy]

well it should help with ibuprofen. Good luck.

[AndyT]

As others have said, the use of low dose aspirin doesn’t completely rule out other NSAIDs such as ibuprofen and diclofenac but they need using with caution and at the lowest effective dose, to minimise risks of bleeding and gastrointestinal problems.

I’ve used both the above for acute injuries without any problems and with my doctors’ agreement.

I can understand your doctor’s caution but if trying without anti-inflammatory drugs isn’t working maybe it’s worth discussing with them again.

[mark382]

I'm on low dose aspirin and GP refuses to give me any anti inflammatory. I also have asthma so things like ibuprofen are are also not prescribed. Although GP is happy for me to use ibuprofen gel to rub on skin. I looked a Tumeric, which I believe contains cucumin. I looked it up online and it says, for Tumeric, that it can bind to iron and stop iron absorption. Not wat I wanted at this stage as I'm anaemic and consultant haematologist won't give me iron tablets as last time me hematocrit went up so quickly I was at risk of a stroke, so been told to eat iron rich foods. So stuck with ibuprofen gel.

[william-Indo in reply to mark382]

If you take tumeric in raw form, pls add some black pepper to increasing the absorb of tumeric

[K-itty]

I'm all about Functional and Integrative medicine. Unfortunately, as it's been stated, with MPN, we suffer inflammation. One treatment I have found extremely helpful is the Feldenkrais Method. A practioner was recommended to me by the Osteopath I was seeing. It's a form of somatic training for the brain and the body...small movements with limited repetitions. One can download some of the movements on YouTube or check out Amazon for a book entitled Functional Feldenkrais movements at home or office. I have found these movements to be a blessing for me.

[Hopetohelp]

I took neurofen off the counter when I had back pain. Only used it for a couple of days and only took one a day together with paracetamol. Don’t know if it’s allowed for us but I could hardly move and it was ok for me. Hope you feel better soon

[Rastavapa]

If your in a legal state medical cannabis or CBD is a good anti-inflammatory,I have a prescription myself and it works excellent for pain in bones ,appetite and wellbeing also.I only take my rux and aspirin now ,it's removed all painkillers ,SSRI and I don't even take my lansoprazole anymore as it's not needed ,it took a good few months for all this to happen but a doctor is on hand to help normally in a clinic.

Take it easy

Nick

[Anag]

I took the natural root. First of all, I changed to an anti-inflammatory dietThen I reduced anything that causes inflammation in my body. then I took out all the chemicals in my food in my cosmetics, and in my house, including all soaps and cleaning agents. This reduced the burden on my immune system greatly.

as an anti-inflammatory, I use turmeric and curcumin. When I do that, I reduce my aspirin to 50mg instead of 100 mg. Other anti-inflammatories are fish oil, which I take Not in capsules, but a tablespoon in the morning and a tablespoon at night. The source Hass to be a very clean one organic and basically from salmon.

hope this helps anag