I haven't posted in a while as I've been working on my mindfullness and trying not to worry so much about my MPN.
Long story short: I've been thinking about how MPNs cause inflammation and seem to also be driven by inflammation. I have a form of arthritis in my hands called Erosive Inflammatory Arthritis. I had a big flare and had to resort to 300mg of Celebrex a day to get it under control. The flare is over and I can stop the Celebrex. While I was on the Celebrex, my bloodwork came back looking quite good. That could be down to a few factors. I started taking 800mg of Pomegranate extract, a known JAK 2 inhibitor. And I stopped eating red meat except for once per week. I already ate a nutritious diet and workout, but this change I made about six months ago seems to help with my main issue of fatigue. I'm much less tired these days even though I still need a nap more days than not.
Anyway, I got to thinking about other meds that are anti-inflammatory. For instance, the antibiotic Doxycycline, in low-doses, is an anti-inflammatory drug. Has anyone else tried other anti-inflammatory medicines to see if they had an effect on their numbers?
I have high platelets with basophilia and I'm teetering on high hematocrit. I was looking at having to start phlebotomies, but got a reprieve as my hematocrit fell to 41%. Whew!
I'd appreciate any thoughts you might have.