Experience of taking Lofepromine.

[Silversquid]

I am a parent of a teenager diagnosed with treatment resistant depression. ECT has recently made minor improvements but now Lofepromine is being suggested. I am concerned about the side effects, the possibility of an increase in suicidal thoughts and many other worries as we have had some nasty past experiences on different meds. This is the first time on a tricyclic antidepressant.

[Louiseone]

I'm sorry to hear that your teenager is experiencing treatment-resistant depression. While I can provide some general information about Lofepromine, it's important to consult with a healthcare professional for specific advice and guidance tailored to your teenager's situation.

Lofepromine, also known as N-Methyl-4-phenylpyridinium iodide, is a medication that belongs to the class of antidepressants called monoamine oxidase inhibitors (MAOIs). MAOIs work by increasing the levels of certain neurotransmitters in the brain, such as serotonin, dopamine, and norepinephrine, which are associated with mood regulation.

[Silversquid in reply to Louiseone]

Hi, thank you for your reply, I appreciate it. We’ve been told by the psychiatrist that it’s a tricyclic medication and my teen has only been told that most only experience things like dry mouth and sleepiness. As parents we’ve yet to discuss face to face but obviously have googled and found that there are a lot worse possible side effects than other types of meds and after our experiences so far, it’s hard to feel that the benefits could outweigh them, especially since nothing that’s been tried so far has helped. I guess I was hoping to hear some real experiences of those who’ve taken it?