I've been suffering with panic attacks and anxiety for about two months and my flight response was constantly on. I have now got to a stage of low mood and feel an overwhelming rush of emotion come out of nowhere and I start to worry about everything negatively. I have been on Sertraline now at 50mg for 13 days. Is this normal? Is it working for me or do I need a higher dose? How I'm feeling is affecting my work and I have no motivation and feel like isolating myself from everyone and being on my own. Appreciate the support. Thanks.