Oxford vaccine

[kingsnorth]

I’m hearing a lot about the Oxford vaccine not being as effective as the Pfizer one what is every bodies thoughts please. I’m 70 and have had the Oxford one l have lupus sjogrens and PBC. My partner who is 67 has had the Pfizer one he has no health problems. It’s all confusing to me.

[Tiggywoos]

Hi Kingsnorth

I’ve heard mixed messages ... not about effectiveness but about different reactions to them .

Sorry don’t know anymore but I’m sure one of the amazing ladies or gents on here will post a link . Take care

[kingsnorth in reply to Tiggywoos]

Thanks for replying

[Paul_Howard Partner LUPUS UK]

Hi kingsnorth ,

We need to be a bit cautious about trying to compare the Oxford/AstraZeneca vaccine and Pfizer/BioNTech vaccines directly, especially if we're going off anecdotal evidence.

So far, there have been no clinical trials directly comparing the two vaccines. In trials of the vaccines, efficacy against symptomatic disease seemed higher for the Pfizer/BioNTech vaccine than for the Oxford/AstraZeneca vaccine. However, differences in study setting, study design, study population (age, ethnicity, social demographics, etc), and efficacy endpoints may account for some of the observed differences.

All the approved vaccines give very high protection against severe disease, which is the primary aim of the first phase of the programme, and both vaccines have good safety profiles.

Therefore, there is currently insufficient evidence to make a recommendation of a specific vaccine for people with underlying conditions such as lupus.

The JCVI does not advise a preference for either vaccine in any specific population. For operational and programmatic reasons, such as to enable more extensive and timely vaccine coverage, one vaccine may be offered in certain settings in preference over another vaccine.

[kingsnorth in reply to Paul_Howard]

Thank you Paul