I was an athlete, now I have a hard time doing short walks or cycling once or twice a week. For the last 3-4 years, I have been feeling tremendous fatigue, brain fog, complete lack of energy /motivation. Occasionally, I feel like I am drunk and slur certain words and I am not on any medications nor do I drink alcohol. All this comes and goes but the fatigue has been almost continuous for the most part. They mentioned stress and depression but it is neither. With that, I am starting to feel some depression because I am not doing what I used to do and am just so tired all of the time. I have been to two doctors and since I have negative ANA they both think it cannot be lupus. My dad had lupus and died of lupus-related problems. They both can't explain why I would have positive DS-DNA but negative ANA. Does anyone have this with their blood tests? If so, any explanation from your doctor. I am so tired of being tired all of the time. Thank you for your help.