I've had a bad few days with eating problems, then reflux. I realised I'd been forgetting to take my omeprazole ( the clue being waking up choking on the reflux - no sign of it yesterday). I take 2x20mg twice a day. I looked up omeprazole again, and found that one rare adverse reaction to it is lupus ( this was from the NHS site). Following up on that, I found the rare adverse reaction is SLE. There are several articles on it. One here
As far as I know, my oesophagul and stomach problems started nearly a year before other symptoms resulted in referral to rheumy. The very high dose of omeprazole I take is in order to prevent the reoccurence of oesophagul and stomach ulcers I had badly.
Just to add I do not have SLE, but others may find this interesting.
Edited to add I wrote this only half awake and may have the terminology wrong. The adverse reactions appear to be skin related only.