Sorry if this is too much information, but do any women suffer very irregular bleeding? I have been using the progesterone-only pill for about 18 months now. When I was taking that I was getting small amounts of blood a couple of times per week, I thought it was just my hormones. In the past 9 months, I have been taking hydroxychloroquine (HCO) and this problem has become less frequent. It seems to happen when I miss a dose of HCO, or when I'm having a lupus flare. Does anyone else experience this as an association with lupus, or could it just be my hormones despite the lupus?