I am an 18 year old girl, who has had lupus for 18 months now. A year ago, after a kidney biopsy I was diagnosed with lupus nephritis class IV, and put on mychophenolate. However after 6 months of this treatment the protein in my urine refused to come down so I was told I had to start chemotherapy! I am currently doing the euro lupus regime (6 fortnightly doses of 500mgs of cytoxan). I have completed 3 doses which I am thankful that I handle well. However the protein in my urine has not started to come down yet and I am getting worried that it won't work! Has anyone had any similar experiences, and if so how long was it before you started to see some pleasing results?