Hello all! I was diagnosed in May 2014 but docs feel Lupus was triggered by the birth of my son in 2012. I have been in a flare for almost five years. I've been on plaquenil for almost two. Briefly, I was put on chloroquine but had a severe reaction to it (diarrhea and vomiting) . My blood work still shows high antibodies to my ds-dna and Ana is still positive. Compared to many, I am sure my Lupus seems well managed but I haven't had a well day in five years. My kidneys are OK, but under functioning a bit. My lungs are OK, but I have chest infections all the time...my joints are awful morning and night, especially my ribs. Fatigue? Sometimes, I have to stop halfway up the stairs to catch my breath. Isn't it time to try another medication? If so, what would be the options? I think it's time for a remission. I am self employed so I can't get any government help but my doc says if I had been working for someone else she'd put me on disability. So what's the criteria for trying something else instead of settling for feeling half dead.