Does anyone else with Lupus have unbearable itching nightly? My GP refuses to believe it is due to Lupus just my immune system playing up. I am beside myself from lack of sleep and the terrible itching. I take pain killers and anti histamine tablets and eventually after many hours the itching will stop. I also drink a lot of water and wondered if it was related to my kidney or liver functions, which are both affected by my Lupus, I have abnormal blood results for my liver, my GP said it is normal for me so nothing to act upon. Could this be related?